Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Jon Cuccui"'
Autor:
Burhan Lehri, Elizabeth Atkins, Timothy A. Scott, Sherif Abouelhadid, Brendan W. Wren, Jon Cuccui
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 6, Pp n/a-n/a (2024)
Abstract The application of bacterial oligosaccharyltransferases (OSTs) such as the Campylobacter jejuni PglB for glycoengineering has attracted considerable interest in glycoengineering and glycoconjugate vaccine development. However, PglB has limit
Externí odkaz:
https://doaj.org/article/a3b5ae37e13f4b36941199417dc21b76
Autor:
Sherif Abouelhadid, Elizabeth R. Atkins, Emily J. Kay, Ian J. Passmore, Simon J. North, Burhan Lehri, Paul Hitchen, Eirik Bakke, Mohammed Rahman, Janine T. Bossé, Yanwen Li, Vanessa S. Terra, Paul R. Langford, Anne Dell, Brendan W. Wren, Jon Cuccui
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Conjugate vaccines produced either by chemical or biologically conjugation have been demonstrated to be safe and efficacious in protection against several deadly bacterial diseases. However, conjugate vaccine assembly and production have sev
Externí odkaz:
https://doaj.org/article/7c268aec51534a47a4626a4fff3d99d6
Autor:
Ricardo Corona-Torres, Prerna Vohra, Cosmin Chintoan-Uta, Abi Bremner, Vanessa S. Terra, Marta Mauri, Jon Cuccui, Lonneke Vervelde, Brendan W. Wren, Mark P. Stevens
Publikováno v:
Vaccines, Vol 12, Iss 4, p 395 (2024)
Campylobacter is a major cause of acute gastroenteritis in humans, and infections can be followed by inflammatory neuropathies and other sequelae. Handling or consumption of poultry meat is the primary risk factor for human campylobacteriosis, and C.
Externí odkaz:
https://doaj.org/article/425311bf8ef64f3aa1a2c9d2faef25d0
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Background Glycoengineering, in the biotechnology workhorse bacterium, Escherichia coli, is a rapidly evolving field, particularly for the production of glycoconjugate vaccine candidates (bioconjugation). Efficient production of glycoconjuga
Externí odkaz:
https://doaj.org/article/9f731b36816a4c29ae3d8c183184edb7
Autor:
Vanessa S. Terra, Marta Mauri, Thippeswamy H. Sannasiddappa, Alexander A. Smith, Mark P. Stevens, Andrew J. Grant, Brendan W. Wren, Jon Cuccui, the Glycoengineering of Veterinary Vaccines consortium (GoVV)
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background Campylobacter is an animal and zoonotic pathogen of global importance, and a pressing need exists for effective vaccines, including those that make use of conserved polysaccharide antigens. To this end, we adapted Protein Glycan C
Externí odkaz:
https://doaj.org/article/9ef74ec04b684752a39faf7ab2b79bf2
Autor:
Marta Mauri, Thippeswamy H. Sannasiddappa, Prerna Vohra, Ricardo Corona-Torres, Alexander A. Smith, Cosmin Chintoan-Uta, Abi Bremner, Vanessa S. Terra, Sherif Abouelhadid, Mark P. Stevens, Andrew J. Grant, Jon Cuccui, Brendan W. Wren, the Glycoengineering of Veterinary Vaccines Consortium
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-26 (2021)
Abstract Background Poultry is the world's most popular animal-based food and global production has tripled in the past 20 years alone. Low-cost vaccines that can be combined to protect poultry against multiple infections are a current global imperat
Externí odkaz:
https://doaj.org/article/47eb9a16750d4941aab1602c1eea67bc
Autor:
Dominika Majorova, Elizabeth Atkins, Henny Martineau, Ivan Vokral, Dorenda Oosterhuis, Peter Olinga, Brendan Wren, Jon Cuccui, Dirk Werling
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
The recent increase in new technologies to analyze host-pathogen interaction has fostered a race to develop new methodologies to assess these not only on the cellular level, but also on the tissue level. Due to mouse-other mammal differences, there i
Externí odkaz:
https://doaj.org/article/8a88886ff37341f3a32874a6163c5e6a
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-13 (2019)
Abstract Background Actinobacillus pleuropneumoniae is the causative agent of porcine pleuropneumonia and represents a major burden to the livestock industry. Virulence can largely be attributed to the secretion of a series of haemolytic toxins, whic
Externí odkaz:
https://doaj.org/article/51deb51677ae4345a1a69a2ffe1cf8fc
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT The substantial rise in multidrug-resistant bacterial infections is a current global imperative. Cumulative efforts to characterize antimicrobial resistance in bacteria has demonstrated the spread of six families of multidrug efflux pumps, o
Externí odkaz:
https://doaj.org/article/0292a43c06454b0bac742e5b297f2e39
Autor:
Sherif Abouelhadid, Simon J. North, Paul Hitchen, Prerna Vohra, Cosmin Chintoan-Uta, Mark Stevens, Anne Dell, Jon Cuccui, Brendan W. Wren
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT In eukaryotes, glycosylation plays a role in proteome stability, protein quality control, and modulating protein function; however, similar studies in bacteria are lacking. Here, we investigate the roles of general protein glycosylation syst
Externí odkaz:
https://doaj.org/article/0d0372c0457a437f9746456acb366609