Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jon Coxhead"'
Autor:
Benjamin J. Whittle, Osagie G. Izuogu, Hannah Lowes, Dasha Deen, Angela Pyle, Jon Coxhead, Rachael A. Lawson, Alison J. Yarnall, Michael S. Jackson, Mauro Santibanez-Koref, Gavin Hudson
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Neurodegeneration in Parkinson’s disease (PD) precedes diagnosis by years. Early neurodegeneration may be reflected in RNA levels and measurable as a biomarker. Here, we present the largest quantification of whole blood linear and circular
Externí odkaz:
https://doaj.org/article/755bcb8608f34a71b0ad793489ea3d40
Autor:
Michael J. Keogh, Wei Wei, Juvid Aryaman, Lauren Walker, Jelle van den Ameele, Jon Coxhead, Ian Wilson, Matthew Bashton, Jon Beck, John West, Richard Chen, Christian Haudenschild, Gabor Bartha, Shujun Luo, Chris M. Morris, Nick S. Jones, Johannes Attems, Patrick F. Chinnery
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Similar to cancers, somatic mutations might lead to neurodegenerative diseases. Here, the authors perform ultra-deep sequencing of 102 genes in 173 adult human brains, detect somatic mutations in 54 brains, and develop a mathematical model to estimat
Externí odkaz:
https://doaj.org/article/4340dcba8f0b45e0b3cd339e05e6fd88