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pro vyhledávání: '"Jon C. Henrikson"'
Autor:
Susan L. Mooberry, Majed S. Gharfeh, K. David Hambright, Jon C. Henrikson, Anne C. Easton, Robert H. Cichewicz, Karen L. Glenn, James D. Easton, Miriam Shadfan
Publikováno v:
Toxicon. 55:1396-1404
Within the last two decades, Prymnesium parvum (golden algae) has rapidly spread into inland waterways across the southern portion of North America and this organism has now appeared in more northerly distributed watersheds. In its wake, golden algae
Publikováno v:
Manual of Industrial Microbiology and Biotechnology
This chapter concentrates on the methodological approaches used to access the products of silent biosynthetic pathways (SBPs), and presents a number of important case studies that are intended to help one evaluate the advantages and disadvantages of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d8dd0a521cfe8e7cd41ba5ee48f2fbd
https://doi.org/10.1128/9781555816827.ch7
https://doi.org/10.1128/9781555816827.ch7
Publikováno v:
Journal of natural products. 74(9)
To date, natural products containing 2-benzyl-4H-pyran-4-one and 2-benzylpyridin-4(1H)-one substructures have been encountered in relatively few fungi outside of the black aspergilli clade. While exploring the occurrence of these compounds among Aspe
Autor:
Jon C. Henrikson, L. Jackson, K. M. Fisch, Robert H. Cichewicz, M. Gipson, Allison F. Gillaspy, Ashley R. Hoover, F. Z. Najar, Heike Wägele
Publikováno v:
Journal of industrial microbiologybiotechnology. 36(9)
Manipulation of the fungal epigenome is hypothesized to be an effective method for accessing natural products from silent biosynthetic pathways. A library of epigenetic modifiers was tested using the fungus Aspergillus niger to determine the impact o
Publikováno v:
Organicbiomolecular chemistry. 7(3)
A new fungal metabolite, nygerone A (), featuring a unique 1-phenylpyridin-4(1H)-one core that had previously not been reported from any natural source, has been obtained from Aspergillus niger using a chemical epigenetics methodology.
Autor:
Robert H. Cichewicz, Russell B. Williams, Jon C. Henrikson, Andrlynn E. Lee, Ashley R. Hoover
Publikováno v:
Organicbiomolecular chemistry. 6(11)
Fungi treated with DNA methyltransferase and histone deacetylase inhibitors exhibited natural product profiles with enhanced chemical diversity demonstrating that small-molecule epigenetic modifiers are effective tools for rationally controlling the