Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jon Burdach"'
KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells
Autor:
Laura J. Norton, Alister P.W. Funnell, Jon Burdach, Beeke Wienert, Ryo Kurita, Yukio Nakamura, Sjaak Philipsen, Richard C.M. Pearson, Kate G.R. Quinlan, Merlin Crossley
Publikováno v:
Blood Advances, Vol 1, Iss 11, Pp 685-692 (2017)
Abstract: Genes encoding the human β-like hemoglobin proteins undergo a developmental switch from fetal γ-globin to adult β-globin expression around the time of birth. β-hemoglobinopathies, such as sickle-cell disease and β-thalassemia, result f
Externí odkaz:
https://doaj.org/article/127389a1449942409be43fa25db88e07
Publikováno v:
Non-coding RNA Research, Vol 1, Iss 1, Pp 3-11 (2016)
Cells communicate with one another to create microenvironments and share resources. One avenue by which cells communicate is through the action of exosomes. Exosomes are extracellular vesicles that are released by one cell and taken up by neighbourin
Externí odkaz:
https://doaj.org/article/0309be66f49e45a2990c905c99f1dca7
Publikováno v:
Journal of Infection and Public Health, Vol 7, Iss 2, Pp 153-160 (2014)
Summary: Background: Ultrasound transducer reprocessing is required to prevent the transmission of infections between patients. In some regions, reprocessing practices are not sufficient to achieve high-level disinfection (HLD), which can result in c
Externí odkaz:
https://doaj.org/article/9374ee414c394c86a7ad28281c380408
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152424 (2016)
Natural selective processes have been known to drive phenotypic plasticity, which is the emergence of different phenotypes from one genome following environmental stimulation. Long non-coding RNAs (lncRNAs) have been observed to modulate transcriptio
Externí odkaz:
https://doaj.org/article/2eac2762273c40fc91413b5944d4e99c
Autor:
Alister P. W. Funnell, Manan Shah, Richard C. M. Pearson, Laura J. Norton, Yukio Nakamura, Gabriella E. Martyn, Merlin Crossley, Jon Burdach, Lu Yang, Kate G. R. Quinlan, Beeke Wienert, Ryo Kurita
Publikováno v:
Nature Genetics. 50:498-503
β-hemoglobinopathies such as sickle cell disease (SCD) and β-thalassemia result from mutations in the adult HBB (β-globin) gene. Reactivating the developmentally silenced fetal HBG1 and HBG2 (γ-globin) genes is a therapeutic goal for treating SCD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d35e0a591f76b1aa13a35f917df59f5e
https://doi.org/10.1038/s41588-018-0085-0
https://doi.org/10.1038/s41588-018-0085-0
Autor:
Kevin V. Morris, Sheena Saayman, Pad Chivukula, Amanda Ackley, Jon Burdach, Kiyoshi Tachikawa, Dieter C. Gruenert, Matthew Clemson, Marc S. Weinberg
Publikováno v:
Molecular Therapy
Cystic fibrosis (CF) is a life-shortening genetic disease. The root cause of CF is heritable recessive mutations that affect the cystic fibrosis transmembrance conductance regulator (CFTR) gene and the subsequent expression and activity of encoded io
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1000f1ab26ea38447e57a17e49b0562e
Autor:
Merlin Crossley, Wooi F. Lim, Richard C. M. Pearson, Alister P. W. Funnell, Jon Burdach, Kate G. R. Quinlan
Publikováno v:
Nucleic Acids Research
Transcription factors are often regarded as having two separable components: a DNA-binding domain (DBD) and a functional domain (FD), with the DBD thought to determine target gene recognition. While this holds true for DNA binding in vitro, it appear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7427542b663cc4d08e1987530a748128
https://doi.org/10.1093/nar/gkv1380
https://doi.org/10.1093/nar/gkv1380
Publikováno v:
Australasian Journal of Ultrasound in Medicine
Infection control and prevention is critical to delivering safe and high‐quality care to patients undergoing sonographic procedures. In Australia comprehensive standards for reprocessing of ultrasound probes are based on the AS/NZS, TGA and ASUM re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb71d3d8f62e8edcaa2105a81f01a6e
https://doi.org/10.1002/j.2205-0140.2015.tb00207.x
https://doi.org/10.1002/j.2205-0140.2015.tb00207.x
Publikováno v:
Infection Control & Hospital Epidemiology. 36:581-584
Intracavity ultrasound transducer handles are not routinely immersed in liquid high-level disinfectants. We show that residual bacteria, including pathogens, persist on more than 80% of handles that are not disinfected, whereas use of an automated de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8169352739a4f1bad4fbba032a0680
https://doi.org/10.1017/ice.2015.12
https://doi.org/10.1017/ice.2015.12
KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells
Autor:
Yukio Nakamura, Jon Burdach, Sjaak Philipsen, Richard C. M. Pearson, Beeke Wienert, Merlin Crossley, Ryo Kurita, Alister P. W. Funnell, Laura J. Norton, Kate G. R. Quinlan
Publikováno v:
Blood advances, 1(11), 685-692. American Society of Hematology
Genes encoding the human β-like hemoglobin proteins undergo a developmental switch from fetal γ-globin to adult β-globin expression around the time of birth. β-hemoglobinopathies, such as sickle-cell disease and β-thalassemia, result from mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2399bdc84723f9949277ac4be9391d4
https://pure.eur.nl/en/publications/a1e3767f-1909-45bf-a69d-c5cae9ec6406
https://pure.eur.nl/en/publications/a1e3767f-1909-45bf-a69d-c5cae9ec6406
