Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jon Blevitt"'
Publikováno v:
Annals of the New York Academy of Sciences. 745:177-186
Autor:
Anders Brunmark, Liming Huang, Kirsten L. Arienti, Kelly J. McClure, J. Guy Breitenbucher, Frank U. Axe, Jon Blevitt
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:1924-1928
In a recent paper, [Arienti, K. L.; Brunmark, A.; Axe, F. U.; McClure, K. M.; Lee, A.; Blevitt, J.; Neff, D. K.; Huang, L.; Crawford, S.; Chennagiri, R. P.; Karlsson, L.; Brietenbucher, J. G. J. Med. Chem.2005, 48, 1873], we described the discovery o
Checkpoint Kinase Inhibitors: SAR and Radioprotective Properties of a Series of 2-Arylbenzimidazoles
Autor:
Anders Brunmark, Danielle K. Neff, Shelby Crawford, Lars Karlsson, Kelly J. McClure, Alice Lee, J. Guy Breitenbucher, Chennagiri R. Pandit, Frank U. Axe, Kristen L. Arienti, Jon Blevitt, Liming Huang
Publikováno v:
Journal of Medicinal Chemistry. 48:1873-1885
The discovery of a series of novel, potent, and highly selective inhibitors of the DNA damage control kinase chk2 is disclosed. Here we report the first SAR study around inhibitors of this kinase. High-throughput screening of purified human chk2 led
Publikováno v:
Biopolymers. 37:157-175
The cell adhesion domain, arginine-glycine-aspartic acid (RGD), has been incorporated into synthetic peptides to perform either of two modes of drug action, antagonist or agonist. Short, conformationally constrained peptides have been developed as an
Publikováno v:
Biopolymers. 37:363-363