Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jon B. Patteson"'
Autor:
William C. Simke, Morgan E. Walker, Logan A. Calderone, Andrew T. Putz, Jon B. Patteson, Caitlin N. Vitro, Cynthia F. Zizola, Matthew R. Redinbo, Maria-Eirini Pandelia, Tyler L. Grove, Bo Li
Publikováno v:
ACS Central Science, Vol 10, Iss 8, Pp 1524-1536 (2024)
Externí odkaz:
https://doaj.org/article/1dac01033a884e3da3bf9eadc381f3d0
Autor:
R. David Britt, L. Henry Bryant, Lizhi Tao, Jon B. Patteson, Andrew T. Putz, William C. Simke, Bo Li
Publikováno v:
Science. 374:1005-1009
A copper-containing antibiotic Bacteria require transition metal ions for biological processes and must also protect themselves against excess metal, which is toxic. Patteson et al . explored how the environmental bacterium Pseudomonas aeruginosa use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ad3c9202809203bb4b0fdc836270639
https://doi.org/10.1126/science.abj6749
https://doi.org/10.1126/science.abj6749
Autor:
Jon B. Patteson, Camille Marie Fortinez, Andrew T. Putz, Juan Rodriguez-Rivas, L. Henry Bryant, Kamal Adhikari, Martin Weigt, T. Martin Schmeing, Bo Li
Publikováno v:
Journal of the American Chemical Society. 144(31)
Dehydroamino acids are important structural motifs and biosynthetic intermediates for natural products. Many bioactive natural products of nonribosomal origin contain dehydroamino acids; however, the biosynthesis of dehydroamino acids in most nonribo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aae1390711fd584037c546163132a07
https://pubmed.ncbi.nlm.nih.gov/35895935
https://pubmed.ncbi.nlm.nih.gov/35895935
Autor:
Jon B, Patteson, Andrew T, Putz, Lizhi, Tao, William C, Simke, L Henry, Bryant, R David, Britt, Bo, Li
Publikováno v:
Science
Metal-binding natural products contribute to metal acquisition and bacterial virulence, but their roles in metal stress response are underexplored. We show that a five-enzyme pathway in Pseudomonas aeruginosa synthesizes a small-molecule copper compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf8f19f0955729fdc2a0be607c9e5cd6
https://pubmed.ncbi.nlm.nih.gov/34793213
https://pubmed.ncbi.nlm.nih.gov/34793213
Publikováno v:
Org Lett
Azabicyclene, an azetidine-containing natural product, was identified using quorum-sensing molecules to upregulate expression of a gene cluster highly conserved in the human pathogen Pseudomonas aeruginosa. Mutational studies of the gene cluster reve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5736f944b738f5da2d771d16d587a9dd
https://doi.org/10.1021/acs.orglett.9b01383
https://doi.org/10.1021/acs.orglett.9b01383
Publikováno v:
Protein Sci
The cellular environment is dynamic and complex, involving thousands of different macromolecules with total concentrations of hundreds of grams per liter. However, most biochemistry is conducted in dilute buffer where the concentration of macromolecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157e3984a04e22581ee0e6c07e3a1ad1
https://doi.org/10.1002/pro.3637
https://doi.org/10.1002/pro.3637
Publikováno v:
Angewandte Chemie. 130:6896-6901
Oxyvinylglycines are a family of nonproteinogenic amino acids featuring an essential vinyl ether conferring mechanism-based inhibition of pyridoxal phosphate enzymes. The gene clusters for a few oxyvinylglycines are known, yet the biosynthetic origin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ab617ce91ab300a8b6f2bacb3ee787
https://doi.org/10.1002/ange.201713419
https://doi.org/10.1002/ange.201713419
Publikováno v:
Biochemistry. 57:61-65
Diketopiperazines (DKPs) are a large group of natural products with diverse structures and biological activities. Bicyclomycin is a broad-spectrum DKP antibiotic with unique structure and function: it contains a highly oxidized bicyclic [4.2.2] ring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62640ef797ee7f466c86f01d445afbb
https://doi.org/10.1021/acs.biochem.7b00943
https://doi.org/10.1021/acs.biochem.7b00943
Autor:
Frank C. Schroeder, Omri M. Finkel, Jeffery L. Dangl, Bo Li, Elisabetta Massolo, Joshua A. Baccile, Tatiana S. Mucyn, Erinn M. O'Neill, Eui Hwan Chung, Jon B. Patteson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Bacterial pathogens cause plant diseases that threaten the global food supply. To control diseases, it is important to understand how pathogenic bacteria evade plant defense and promote infection. We identify from the phytopathogen Pseud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5594c609bd69e4a97f41154b7bb291f8
https://resolver.caltech.edu/CaltechAUTHORS:20180920-144411925
https://resolver.caltech.edu/CaltechAUTHORS:20180920-144411925
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc4284c93bbb85095905f3b5d4a5ae68
https://doi.org/10.1096/fasebj.2018.32.1_supplement.796.4
https://doi.org/10.1096/fasebj.2018.32.1_supplement.796.4