Výsledky vyhledávání - "Jon B. Court"

CT-planned accelerated hypofractionated radiotherapy in the radical treatment of non-small cell lung cancer

Autor: Jason F. Lester, Jon B Court, Nayyer Iqbal, Fergus Macbeth, Alison Brewster

Publikováno v: Lung Cancer. 45:237-242

Surgery is the standard treatment for stage I, II and certain stage IIIA non-small cell lung cancers (NSCLC). A proportion of patients with technically operable NSCLC do not undergo surgery because of significant co-morbidity or refusal, and radical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b35871e1c465b8c5c6280ee8352315
https://doi.org/10.1016/j.lungcan.2004.01.018

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Single cell tracking reveals that Msh2 is a key component of an early-acting DNA damage-activated G2 checkpoint

Autor: Rachel J. Errington, Sally Claire Chappell, Owen J. Sansom, Alan Richard Clarke, Jon B. Court, Paul J. Smith, Nuria Marquez

Publikováno v: Oncogene. 22:7642-7648

Dysfunction of cell-cycle checkpoints in DNA mismatch repair (MMR)-deficient cells in response to DNA damage has implications for anticancer therapy and genetic instability. We have studied the cell-cycle effects of MMR deficiency (Msh2(-/-)) in prim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ecc6fda248a5ad8774edc9fd9e37c7
https://doi.org/10.1038/sj.onc.1206876

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Correlation between the Clonogenic Initial Slope and the Response of Polykaryon-Forming Units: The Behavior of Strains Defective inXRCC5andATMand the Heritability of Small Variations in Radioresponse

Autor: Ifor Delme Bowen, S. Venables, H. E. Davies, Jon B. Court, Lorenzo Manti

Publikováno v: Radiation Research. 154:650-658

The polykaryon-forming unit (PFU) assay measures the survival of multiple cycles of DNA synthesis after exposure to ionizing radiation, and it is known that there is a strong correlation between the slope of the PFU dose-response curve and the clonog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f47c58ec3d382f3ae6bd8c681f1c4c
https://doi.org/10.1667/0033-7587(2000)154[0650:cbtcis]2.0.co

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Apoptosis is a mode of cell death in the polykaryon-forming unit assay

Autor: Ifor Delme Bowen, Malcolm David Mason, Jon B. Court, Lorenzo Manti

Publikováno v: Cell biology international. 24(7)

In the polykaryon-forming unit (PFU) assay, which defines cell survival as the ability to form a cytochalasin-induced polykaryon of predetermined ploidy, the mode of PFU deletion is not known. Incubation of L5178Y-S PFU in cytochalasin resulted in po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91aeee7ec46cc29263fc5e1efeed2a54
https://pubmed.ncbi.nlm.nih.gov/10875889

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50 Mitomycin C, vinblastine and carboplatin: Effective palliativechemotherapy for non-small cell lung cancer (NSCLC)

Autor: C. Morgan, Emma Hudson, Jon B Court, Jason F. Lester, Alison Brewster

Publikováno v: Lung Cancer. 49:S391-S392

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9a6b2d5addcb68158cf9e15d60038fa
https://doi.org/10.1016/s0169-5002(05)81521-1

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O-24 Hypofractionated radical radiotherapy for medically inoperable non-small cell lung cancer patients

Autor: Jason F. Lester, Fergus Macbeth, Nayyer Igbal, Jon B Court, Alison Brewster

Publikováno v: Lung Cancer. 41:S11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0eae7bb2b3d8b59a89d1f8e085069af3
https://doi.org/10.1016/s0169-5002(03)91682-5

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