Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Jon B Klein"'
Autor:
Kevin M Wheelock, Jian Cai, Helen C Looker, Michael L Merchant, Robert G Nelson, Gudeta D Fufaa, E Jennifer Weil, Harold I Feldman, Ramachandran S Vasan, Paul L Kimmel, Brad H Rovin, Michael Mauer, Jon B Klein, CKD Biomarkers Consortium
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180964 (2017)
ObjectiveTo examine the association of bradykinin and related peptides with the development of diabetic nephropathy lesions in 243 participants with type 1 diabetes (T1D) from the Renin-Angiotensin System Study who, at baseline, were normoalbuminuric
Externí odkaz:
https://doaj.org/article/19eb20ea55884b679802c76a47f54cd1
Autor:
Shunying Jin, Michael L Merchant, Jeffrey D Ritzenthaler, Kenneth R McLeish, Eleanor D Lederer, Edilson Torres-Gonzalez, Mostafa Fraig, Michelle T Barati, Alex B Lentsch, Jesse Roman, Jon B Klein, Madhavi J Rane
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121637 (2015)
Immune-complexes play an important role in the inflammatory diseases of the lung. Neutrophil activation mediates immune-complex (IC) deposition-induced acute lung injury (ALI). Components of gamma amino butyric acid (GABA) signaling, including GABA B
Externí odkaz:
https://doaj.org/article/241d62c110c54c75a52fcfa8b728e13c
Autor:
Nichola C Garbett, Michael L Merchant, C William Helm, Alfred B Jenson, Jon B Klein, Jonathan B Chaires
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84710 (2014)
Improved methods for the accurate identification of both the presence and severity of cervical intraepithelial neoplasia (CIN) and extent of spread of invasive carcinomas of the cervix (IC) are needed. Differential scanning calorimetry (DSC) has rece
Externí odkaz:
https://doaj.org/article/09cf011b9a9d40928773b730e7dea6fe
Autor:
Ada Fiorini, Rukhsana Sultana, Eugenio Barone, Giovanna Cenini, Marzia Perluigi, Cesare Mancuso, Jian Cai, Jon B Klein, Daret St Clair, D Allan Butterfield
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49846 (2012)
The tumor suppressor protein p53 has been described "as the guardian of the genome" for its crucial role in regulating the transcription of numerous genes responsible for cells cycle arrest, senescence, or apoptosis in response to various stress sign
Externí odkaz:
https://doaj.org/article/c32e12a948174941a8e250ab6b5b172b
Autor:
Soumya M. Turaga, Mihaela E. Sardiu, Vikalp Vishwakarma, Amrita Mitra, Leonidas E. Bantis, Rashna Madan, Michael L. Merchant, Jon B. Klein, Glenson Samuel, Andrew K. Godwin
Publikováno v:
Frontiers in Molecular Biosciences. 10
Ewing Sarcoma (EWS) is the second most common osseous malignancy in children and young adults after osteosarcoma, while it is the fifth common osseous malignancy within adult age population. The clinical presentation of EWS is quite often non-specifi
Autor:
Sagar Bhayana, Yue Zhao, Michael Merchant, Timothy Cummins, Julie A. Dougherty, Yu Kamigaki, Wimal Pathmasiri, Susan McRitchie, Laura H. Mariani, Susan Sumner, Jon B. Klein, Lang Li, William E. Smoyer, John Mahan, Hiren Patel, Richard F. Ransom, Cynthia Pan, Denis F. Geary, Myra L. Chang, Keisha L. Gibson, Franca M. Iorember, Patrick D. Brophy, Tarak Srivastava, Larry A. Greenbaum
Publikováno v:
Kidney International Reports.
Autor:
Julia M. Corman, Joshua L Fuqua, Krystal Teasley Hamorsky, Kathleen Kitterman, Shirish Barve, Donghoon Chung, Kenneth E. Palmer, Marti Gardner, Adrienne M. Bushau-Sprinkle, Joseph M Flynn, Joongho Joh, Rachel J. Keith, Aruni Bhatnagar, Amanda B. Lasnik, Jon B. Klein, Smita Ghare, Jennifer K. DeMarco
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Serological assays intended for diagnosis, sero-epidemiologic assessment, and measurement of protective antibody titers upon infection or vaccination are essential for managing the SARS-CoV-2 pandemic. Serological assays measuring the antibody respon
Autor:
Jon B. Klein, Tiffany Caza, Issa Kawalit, Fred Clayton, Christian Herzog, Tim Cummins, Ronald Sjöberg, Brandi L Williams, Rick D. Edmondson, John M. Arthur, Michael L. Merchant, Monica P. Revelo, Jo Abraham, Tianxin Yang, Laith Al-Rabadi, Nicole K. Andeen, Nirupama Ramkumar, Laurence H. Beck, Aylin R. Rodan, Daniel W. Wilkey, Jeremy Chien, Chang Jiang Zou, Claire Trivin-Avillach, Willisa Liou, Edwin Lin, Christopher P. Larsen, Norifumi Hayashi, Aaron J. Storey
Publikováno v:
J Am Soc Nephrol
Background Identification of target antigens PLA2R, THSD7A, NELL1, or Semaphorin-3B can explain the majority of cases of primary membranous nephropathy (MN). However, target antigens remain unidentified in 15%-20% of patients. Methods A multipronged
Autor:
Brad H. Rovin, Cherri Bott, Michael L. Merchant, Mikayla Jones, Sergey V. Brodsky, Tibor Nadasdy, Daniel W. Wilkey, Anjali A. Satoskar, Lianbo Yu, Samir V. Parikh, Haikady N. Nagaraja, John P. Shapiro, Jon B. Klein
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Staphylococcus infection-associated glomerulonephritis (SAGN) and primary IgA nephropathy (IgAN) are separate disease entities requiring different treatment approaches. However, overlapping histologic features may cause a diagnostic dilemma. An explo
Autor:
Xiaobo Liang, Jon B. Klein, Kathleen A. Neville, Atif A. Ahmed, Safinur Atay, Vincent S. Staggs, Jennifer Crow, Michael L. Merchant, Kris Laurence, Devin C. Koestler, Andrew K. Godwin, Glenson Samuel, Emily Nissen
Publikováno v:
Oncotarget
Purpose Ewing Sarcoma Family of Tumors (ESFT), the second most common pediatric osseous malignancy, are characterized by the pathognomonic chromosomal EWS-ETS translocation. Outside of tumor biopsy, no clinically relevant ESFT biomarkers exist. Addit