Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jon Arne Kro Birkeland"'
Autor:
Morten Munkvik, Per Kristian Lunde, Jan Magnus Aronsen, Jon Arne Kro Birkeland, Ivar Sjaastad, Ole M Sejersted
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22695 (2011)
During isometric contractions, slow twitch soleus muscles (SOL) from rats with chronic heart failure (chf) are more fatigable than those of sham animals. However, a muscle normally shortens during activity and fatigue development is highly task depen
Externí odkaz:
https://doaj.org/article/25cc24b0288746fa8fd2de45edb78a5a
Autor:
William E. Louch, Ivar Sjaastad, Unni Lie Henriksen, Jan Magnus Aronsen, Janny Bøkenes, Jon Arne Kro Birkeland, Ole M. Sejersted
Publikováno v:
Basic Research in Cardiology. 103:328-344
The reduced power of the failing heart can be ascribed to a combination of reduced force and slower contraction. We hypothesized that these two properties are due to different cellular mechanisms. We measured contraction parameters both in vivo and i
Autor:
Ivar Sjaastad, Jon Arne Kro Birkeland, William E. Louch, Ole M. Sejersted, Fredrik Swift, Ulla H. Enger, Nils Tovsrud, Jan Magnus Aronsen
Publikováno v:
Cardiovascular Research. 78:71-78
The Na+/K+-ATPase (NKA) alpha2-isoform is preferentially located in the t-tubules of cardiomyocytes and is functionally coupled to the Na+/Ca(+-exchanger (NCX) and Ca2+ regulation through intracellular Na+ concentration ([Na+]i). We hypothesized that
Autor:
Trond Brattelid, Tor Skomedal, E. R. Moberg, Reidar Bjørnerheim, Finn Olav Levy, Jan-Bjørn Osnes, Jon Arne Kro Birkeland, Ole M. Sejersted, Kurt A. Krobert, Eirik Qvigstad, Ivar Sjaastad
Publikováno v:
British Journal of Pharmacology. 150:143-152
Background and purpose: Positive inotropic responses (PIR) to 5-hydroxytryptamine (5-HT) are induced in the left ventricle (LV) in rats with congestive heart failure (CHF); this is associated with upregulation of the Gs-coupled 5-HT4 receptor. We inv
Autor:
Ivar Sjaastad, Jan-Bjørn Osnes, Jon Arne Kro Birkeland, Trond Brattelid, Kurt A. Krobert, Finn Olav Levy, Tor Skomedal, Eirik Qvigstad, Ole M. Sejersted, Alberto J. Kaumann, Kjetil Wessel Andressen
Publikováno v:
Cardiovascular Research. 65:869-878
Background : Current pharmacological treatment of congestive heart failure (CHF) addresses changes in neurohumoral stimulation or cardiac responsiveness to such stimulation. Yet, undiscovered neurohumoral changes, adaptive or maladaptive, may occur i
Autor:
Tor Skomedal, Finn Olav Levy, Ivar Sjaastad, Eirik Qvigstad, Silje Veslemøy Bekkevold, Dagny Sandnes, Jon Arne Kro Birkeland, Trond Brattelid, Lise Román Moltzau, Jan-Bjørn Osnes
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 9, p e45489 (2012)
PLoS ONE, Vol 7, Iss 9, p e45489 (2012)
A positive inotropic responsiveness to serotonin, mediated by 5-HT(4) and 5-HT(2A) receptors, appears in the ventricle of rats with post-infarction congestive heart failure (HF) and pressure overload-induced hypertrophy. A hallmark of HF is a transit
Autor:
Per Kristian Lunde, Morten Munkvik, Jon Arne Kro Birkeland, Ole M. Sejersted, Ivar Sjaastad, Jan Magnus Aronsen
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22695 (2011)
PLoS ONE
PLoS ONE
During isometric contractions, slow twitch soleus muscles (SOL) from rats with chronic heart failure (chf) are more fatigable than those of sham animals. However, a muscle normally shortens during activity and fatigue development is highly task depen
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene
Autor:
Ju Chen, Geir Christensen, Kristin B. Andersson, Alexandra Vanessa Finsen, Jon Arne Kro Birkeland, Ole M. Sejersted, Jeffery D. Molkentin, William E. Louch, Kenneth R. Chien, Ivar Sjaastad, Yibin Wang
Publikováno v:
Journal of molecular and cellular cardiology. 47(2)
The sarco(endo)plasmic reticulum calcium ATPase 2 (SERCA2) transports Ca(2+) from cytosol into the sarcoplasmic reticulum (SR) of cardiomyocytes, thereby maintaining the store of releasable Ca(2+) necessary for contraction. Reduced SERCA function has
Autor:
Finn Olav Levy, Jan-Bjørn Osnes, Ivar Sjaastad, Hilde Eikemo, A. Glende, Jon Arne Kro Birkeland, Erik Qvigstad, R.I. Hussain, Kurt A. Krobert, Tor Skomedal
Publikováno v:
British journal of pharmacology. 156(4)
Background and purpose: Muscarinic stimulation increases myofilament Ca2+ sensitivity with no apparent inotropic response in normal rat myocardium. Increased myofilament Ca2+ sensitivity is a molecular mechanism promoting increased contractility in f
Autor:
Ivar Sjaastad, Jon Arne Kro Birkeland, Fredrik Swift, Ole M. Sejersted, Ulla H. Enger, Per Kristian Lunde, Finn Olav Levy, Eirik Qvigstad, Nils Tovsrud
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 293(4)
Rats with congestive heart failure (CHF) develop ventricular inotropic responsiveness to serotonin (5-HT), mediated through 5-HT2A and 5-HT4 receptors. Human ventricle is similarly responsive to 5-HT through 5-HT4 receptors. We studied isolated ventr