Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Jon A. Wright"'
Autor:
Davide Bernardi, David Shannahoff-Khalsa, Jeff Sale, Jon A. Wright, Luciano Fadiga, David Papo
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
We study how obsessive-compulsive disorder (OCD) affects the complexity and time-reversal symmetry-breaking (irreversibility) of the brain resting-state activity as measured by magnetoencephalography (MEG). Comparing MEG recordings from OCD patients
Externí odkaz:
https://doaj.org/article/57b2b129698e4a46a50904d185df4832
Publikováno v:
eLife, Vol 13 (2024)
Experimental detection of residues critical for protein–protein interactions (PPI) is a time-consuming, costly, and labor-intensive process. Hence, high-throughput PPI-hot spot prediction methods have been developed, but they have been validated us
Externí odkaz:
https://doaj.org/article/02fbed149f19420a840b80310265b0b7
Autor:
Giuditta Perversi, Elise Pachoud, James Cumby, Jessica M. Hudspeth, Jon P. Wright, Simon A. J. Kimber, J. Paul Attfield
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-6 (2019)
The Verwey transition in magnetite was reported 80 years ago but identifying the underlying mechanism has been difficult. Here the authors show that structural distortions associated with the Verwey transition emerge as local fluctuations at the Curi
Externí odkaz:
https://doaj.org/article/4b53c26b1bcb42e1b9f2ad85fd2dd6ff
Autor:
Wei Liu, Zhouqing Luo, Yun Wang, Nhan T. Pham, Laura Tuck, Irene Pérez-Pi, Longying Liu, Yue Shen, Chris French, Manfred Auer, Jon Marles-Wright, Junbiao Dai, Yizhi Cai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Pathway optimization and chassis engineering are usually carried out in a step-wise and trial-and-error manner. Here the authors present ’SCRaMbLE-in’ that combines in-vitro pathway rapid prototyping with in-vivo genome integration and optimizati
Externí odkaz:
https://doaj.org/article/ad81529cd72f4cf5b421bbb08fbc1ca6
Autor:
Stacey L. Heaver, Henry H. Le, Peijun Tang, Arnaud Baslé, Claudia Mirretta Barone, Dai Long Vu, Jillian L. Waters, Jon Marles-Wright, Elizabeth L. Johnson, Dominic J. Campopiano, Ruth E. Ley
Publikováno v:
Heaver, S L, Le, H H, Tang, P, Baslé, A, Mirretta Barone, C, Vu, D L, Waters, J L, Marles-Wright, J, Johnson, E L, Campopiano, D J & Ley, R E 2022, ' Characterization of inositol lipid metabolism in gut-associated Bacteroidetes ', Nature Microbiology, vol. 7, no. 7, pp. 986-1000 . https://doi.org/10.1038/s41564-022-01152-6
Inositol lipids are ubiquitous in eukaryotes and have finely tuned roles in cellular signalling and membrane homoeostasis. In Bacteria, however, inositol lipid production is relatively rare. Recently, the prominent human gut bacterium Bacteroides the
Autor:
Ben Ashley, Arnaud Baslé, Mariyah Sajjad, Ahmed el Ashram, Panayiota Kelis, Jon Marles-Wright, Dominic J. Campopiano
Publikováno v:
Ashley, B, Baslé, A, Sajjad, M, El ashram, A, Kelis, P, Marles-Wright, J & Campopiano, D J 2023, ' Versatile Chemo-Biocatalytic Cascade Driven by a Thermophilic and Irreversible C–C Bond-Forming α-Oxoamine Synthase ', ACS Sustainable Chemistry & Engineering . https://doi.org/10.1021/acssuschemeng.3c00243
We report a chemo-biocatalytic cascade for the synthesis of substituted pyrroles, driven by the action of an irreversible, thermostable, pyridoxal 5′-phosphate (PLP)-dependent, C–C bond-forming biocatalyst (ThAOS). The ThAOS catalyzes the Claisen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71dde821bc1edc2c2801974a4f4506b0
https://hdl.handle.net/20.500.11820/d2808b3e-21c3-4a16-847e-e65ba8602c5c
https://hdl.handle.net/20.500.11820/d2808b3e-21c3-4a16-847e-e65ba8602c5c
Autor:
Ani Paloyan, Armen Sargsyan, Mariam D. Karapetyan, Artur Hambardzumyan, Sergey Kocharov, Henry Panosyan, Karine Dyukova, Marina Kinosyan, Anna Krüger, Cecilia Piergentili, Will A. Stanley, Arnaud Baslé, Jon Marles-Wright, Garabed Antranikian
N-Carbamoyl-β-Alanine Amidohydrolase (CβAA) constitute one of the most important groups of industrially relevant enzymes used in production of optically pure amino acids and derivatives. In this study, a N-carbamoyl-β-alanine amidohydrolase encodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67437302b9fd251e02a2412bebc960e9
https://doi.org/10.1101/2023.05.04.538398
https://doi.org/10.1101/2023.05.04.538398
Publikováno v:
Journal of Chemical Information and Modeling. 62:1052-1060
Publikováno v:
ACS synthetic biology. 11(11)
The continual demand for specialized molecular cloning techniques that suit a broad range of applications has driven the development of many different cloning strategies. One method that has gained significant traction is Golden Gate assembly, which
Autor:
Veronika Heinz, Wenke Jäckel, Susann Kaltwasser, Laura Cutugno, Patricia Bedrunka, Anica Graf, Alexander Reder, Stephan Michalik, Vishnu M. Dhople, M. Gregor Madej, Maria Conway, Marcus Lechner, Katharina Riedel, Gert Bange, Aoife Boyd, Uwe Völker, Richard J. Lewis, Jon Marles-Wright, Christine Ziegler, Jan Pané-Farré
Publikováno v:
Communications Biology. 5
Stressosomes are stress-sensing protein complexes widely conserved among bacteria. Although a role in the regulation of the general stress response is well documented in Gram-positive bacteria, the activating signals are still unclear, and little is