Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jon A Allnutt"'
Autor:
Joanna Bacon, Luke J Alderwick, Jon A Allnutt, Evelina Gabasova, Robert Watson, Kim A Hatch, Simon O Clark, Rose E Jeeves, Alice Marriott, Emma Rayner, Howard Tolley, Geoff Pearson, Graham Hall, Gurdyal S Besra, Lorenz Wernisch, Ann Williams, Philip D Marsh
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87329 (2014)
A key feature of Mycobacterium tuberculosis is its ability to become dormant in the host. Little is known of the mechanisms by which these bacilli are able to persist in this state. Therefore, the focus of this study was to emulate environmental cond
Externí odkaz:
https://doaj.org/article/c11cea27e6004c5da7415a8a6a12a1b4
Autor:
Joanna Bacon, Charlotte L. Hendon-Dunn, Thomas Keating, Jon C. Allnutt, Luke J. Alderwick, Samuel Lethbridge, Stephen Thomas, Stephen Taylor
Publikováno v:
The Cell Surface, Vol 7, Iss, Pp 100065-(2021)
The Cell Surface
The Cell Surface
The development of new vaccines for TB needs to be underpinned by an understanding of both the molecular and cellular mechanisms of host-pathogen interactions and how the immune response can be modulated to achieve protection from disease. Complement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a663dfcc09d5f0c87ac414d9c8542371
http://www.sciencedirect.com/science/article/pii/S2468233021000189
http://www.sciencedirect.com/science/article/pii/S2468233021000189
Autor:
Rose E Jeeves, Alice A N Marriott, Steven T Pullan, Kim A Hatch, Jon C Allnutt, Irene Freire-Martin, Charlotte L Hendon-Dunn, Robert Watson, Adam A Witney, Richard H Tyler, Catherine Arnold, Philip D Marsh, Timothy D McHugh, Joanna Bacon
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138253 (2015)
An important aim for improving TB treatment is to shorten the period of antibiotic therapy without increasing relapse rates or encouraging the development of antibiotic-resistant strains. In any M. tuberculosis population there is a proportion of bac
Externí odkaz:
https://doaj.org/article/b77774f4b89f45aa86fd10187fd3db40
Autor:
Jon C. Allnutt, Joanna Bacon, Charlotte L. Hendon-Dunn, Alice A. N. Marriott, Henry Pertinez, Kim A. Hatch, Geraint Davies
Publikováno v:
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Modulation of growth rate in Mycobacterium tuberculosis is key to its survival in the host; particularly with regard to its adaptation during chronic infection when the growth rate is very slow. The resulting physiological changes will influence the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036e42506787d01972aaf6a6a76c53ac
https://doi.org/10.1128/aac.00570-19
https://doi.org/10.1128/aac.00570-19
Autor:
Charlotte L, Hendon-Dunn, Henry, Pertinez, Alice A N, Marriott, Kim, Hatch, Jon C, Allnutt, Geraint, Davies, Joanna, Bacon
Publikováno v:
Antimicrobial Agents and Chemotherapy
Modulation of the growth rate in Mycobacterium tuberculosis is key to its survival in the host, particularly with regard to its adaptation during chronic infection, when the growth rate is very slow. The resulting physiological changes influence the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6dec4200153ca85bff4e0fe176bd92b0
https://pubmed.ncbi.nlm.nih.gov/31527023
https://pubmed.ncbi.nlm.nih.gov/31527023
Autor:
Rose E. Jeeves, Philip Marsh, Jon C. Allnutt, Kim A. Hatch, Rebecca Devine, Steven T. Pullan, Joanna Bacon, Charlotte L. Hendon-Dunn
Publikováno v:
BMC Infectious Diseases
Background Pyrazinamide (PZA) plays an essential part in the shortened six-month tuberculosis (TB) treatment course due to its activity against slow-growing and non-replicating organisms. We tested whether PZA preferentially targets slow growing cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f863a6833f0903a4d579bc8b16550e98
https://pubmed.ncbi.nlm.nih.gov/27184366
https://pubmed.ncbi.nlm.nih.gov/27184366
Autor:
Adam A. Witney, Timothy D. McHugh, Rose E. Jeeves, Kim A. Hatch, Richard H. Tyler, Philip Marsh, Robert J. Watson, Steven T. Pullan, Charlotte L. Hendon-Dunn, Irene Freire-Martin, Jon C. Allnutt, Alice A. N. Marriott, Joanna Bacon, Catherine Arnold
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 9, p e0138253 (2015)
PLoS ONE, Vol 10, Iss 9, p e0138253 (2015)
An important aim for improving TB treatment is to shorten the period of antibiotic therapy without increasing relapse rates or encouraging the development of antibiotic-resistant strains. In any M. tuberculosis population there is a proportion of bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9282206fc8b7e3a7bb92fb2ba4925d
https://doi.org/10.1371/journal.pone.0138253
https://doi.org/10.1371/journal.pone.0138253
Autor:
Thomas Keating, Samuel Lethbridge, Jon C. Allnutt, Charlotte L. Hendon-Dunn, Stephen R. Thomas, Luke J. Alderwick, Stephen C. Taylor, Joanna Bacon
Publikováno v:
The Cell Surface, Vol 7, Iss , Pp 100065- (2021)
The development of new vaccines for TB needs to be underpinned by an understanding of both the molecular and cellular mechanisms of host-pathogen interactions and how the immune response can be modulated to achieve protection from disease. Complement
Externí odkaz:
https://doaj.org/article/37062073aa574ee2953b77b48421864b