Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jonás Samuel PÉREZ-BLANCO"'
Autor:
Hinojal Zazo, Eduardo Lagarejos, Manuel Prado-Velasco, Sergio Sánchez-Herrero, Jenifer Serna, Almudena Rueda-Ferreiro, Ana Martín-Suárez, M. Victoria Calvo, Jonás Samuel Pérez-Blanco, José M. Lanao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Each year, infections caused around the 25% of neonatal deaths. Early empirical treatments help to reduce this mortality, although optimized dosing regimens are still lacking. The aims were to develop and validate a gentamicin physiologically-based p
Externí odkaz:
https://doaj.org/article/2cdf1a2f1cf640a59597966228f0359c
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2731 (2022)
Model-informed precision dosing (MIPD) is an advanced quantitative approach focusing on individualized dosage optimization, integrating complex mathematical and statistical models of drugs and disease combined with individual demographic and clinical
Externí odkaz:
https://doaj.org/article/ade16dd6b3f14e4cbbb3a405e64f8a82
Autor:
Paulo Teixeira-da-Silva, Jonás Samuel Pérez-Blanco, Dolores Santos-Buelga, María José Otero, María José García
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 811 (2022)
(1) Background: The aim of this study was to explore the valproic acid (VPA) pharmacokinetic characteristics in a large population of pediatric and adult Caucasian patients and to establish a robust population pharmacokinetic (PopPK) model. (2) Metho
Externí odkaz:
https://doaj.org/article/003e61eef49a486dac1edaf3a5b524a7
Autor:
Jonás Samuel Pérez-Blanco, Eva María Sáez Fernández, María Victoria Calvo, José M. Lanao, Ana Martín-Suárez
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 264 (2021)
This study aimed to evaluate the potential efficacy and safety of the amikacin dosage proposed by the main guidelines and to develop an interactive nomogram, especially focused on the potential impact of albumin on initial dosage recommendation. The
Externí odkaz:
https://doaj.org/article/07fc9c1da8d549fe86b30204f3ac4b02
Autor:
Francisco J. García-Peñalvo, Juan Cruz-Benito, Cristina Maderuelo, Jonás Samuel Pérez-Blanco, Ana Martín-Suárez
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
This paper discusses how cloud-based architectures can extend and enhance the functionality of the training environments based on virtual worlds and how, from this cloud perspective, we can provide support to analysis of training processes in the are
Externí odkaz:
https://doaj.org/article/0e0ea4433a6b4b48bc8a4ea434386627
Autor:
Fermín Sánchez-Guijo, Silvia Jiménez Cabrera, Otero Mj, Aránzazu Zarzuelo Castañeda, Álvaro Corral Alaejos, Jonás Samuel Pérez-Blanco
Publikováno v:
British Journal of Clinical Pharmacology. 88:1913-1924
Aims Imatinib is considered the standard first line treatment in newly diagnosed patients with chronic-phase myeloid leukaemia (CML). Several imatinib population pharmacokinetic (popPK) models have been developed. However, their predictive performanc
Autor:
Diego PEÑA-LORENZO, Noemí REBOLLO, José German SÁNCHEZ-HERNÁNDEZ, Jonás Samuel PÉREZ-BLANCO, Lourdes VÁZQUEZ-LÓPEZ, María José OTERO, Aránzazu ZARZUELO-CASTAÑEDA
An ultra-performance liquid chromatography ultraviolet detector (UPLC-UV) method for quantifying isavuconazole in plasma has been developed. The method involves simple plasma precipitation by UPLC with a reversed phase C18 column at 40ºC coupled wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74e0fe87c121eb7128cfe110df0a7887
https://doi.org/10.21203/rs.3.rs-1836242/v1
https://doi.org/10.21203/rs.3.rs-1836242/v1
Autor:
MJ Garcia, Jonás Samuel Pérez-Blanco, Dolores Santos Buelga, Paulo Teixeira-da-Silva, Maria Jose Otero
Publikováno v:
Pharmaceutics; Volume 14; Issue 4; Pages: 811
(1) Background: The aim of this study was to explore the valproic acid (VPA) pharmacokinetic characteristics in a large population of pediatric and adult Caucasian patients and to establish a robust population pharmacokinetic (PopPK) model. (2) Metho
Publikováno v:
Pharmaceutics. 14:2731
Model-informed precision dosing (MIPD) is an advanced quantitative approach focusing on individualized dosage optimization, integrating complex mathematical and statistical models of drugs and disease combined with individual demographic and clinical
Autor:
Juan Jose Perez-Ruixo, Caly Chien, Oliver Ackaert, Daniele Ouellet, Carlos Perez-Ruixo, Jonás Samuel Pérez-Blanco, Margaret K. Yu
Publikováno v:
Clinical Pharmacokinetics. 59:229-244
Apalutamide is a next-generation androgen receptor inhibitor approved for treatment of subjects with high-risk, non-metastatic, castration-resistant prostate cancer (NM-CRPC). The objective of this study was to characterize the population pharmacokin