Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jon, Patterson"'
Autor:
Hany Elsheikha, Jon Patterson
This clinically oriented new volume brings together a wide variety of cases and clinical situations which relate to diseases caused by parasitic agents primarily in small animals and domestic livestock. It includes some cases involving some wild and
Autor:
Lana, Kaiser, John, Davis, Jon, Patterson, Ryan F, Boyd, N Bari, Olivier, George, Bohart, Kenneth A, Schwartz
Publikováno v:
Comparative medicine. 57(4)
Cardiac events, including heart failure and arrhythmias, are the leading cause of death in patients with beta thalassemia. Although cardiac arrhythmias in humans are believed to result from iron overload, excluding confounding factors in the human po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8be828b1aa0371496661888c2d9c35a
https://pubmed.ncbi.nlm.nih.gov/17803053
https://pubmed.ncbi.nlm.nih.gov/17803053
Autor:
Asimina T. Georges, Julian Adams, James R Porter, Janid A. Ali, Emmanuel Normant, Yun Gao, Roger H. Pak, Jie Ge, Vito J. Palombella, Thomas T. Tibbitts, Louis Grenier, Marlene S Dembski, Jeffrey K. Tong, Jon Patterson, Jens Sydor
Publikováno v:
Journal of medicinal chemistry. 49(15)
17-Allylamino-17-demethoxygeldanamycin (17-AAG)1 is a semisynthetic inhibitor of the 90 kDa heat shock protein (Hsp90) currently in clinical trials for the treatment of cancer. However, 17-AAG faces challenging formulation issues due to its poor solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0ce3785fbf55bd027b3985ccdd2857
https://pubmed.ncbi.nlm.nih.gov/16854066
https://pubmed.ncbi.nlm.nih.gov/16854066
Autor:
David Grayzel, Julian Adams, Ken Anderson, Vito Palombella, Jeffrey Tong, Emmanuel Normant, Jon Patterson, John Walker, Jill Goddard, Jens Sydor, Amitabha Mazumder, Paul Richardson, David Siegel, Sundar Jagannath
Publikováno v:
Blood. 106:2560-2560
IPI-504 is a novel, water-soluble Heat Shock Protein 90 (Hsp90) inhibitor. It is the chemical reduction product of 17-AAG, a well-characterized Hsp90 inhibitor. 17-AAG is currently in clinical trials, but suffers from very poor aqueous solubility and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c80bfe4e19eb163281d2feab72445375
https://doi.org/10.1182/blood.v106.11.2560.2560
https://doi.org/10.1182/blood.v106.11.2560.2560
Autor:
Jon Patterson, Vito J. Palombella, James H. Porter, David Grayzel, Asimina T. Georges, John P. Barrett, Christine Pien, Adams Julian, Jennie Ge, Jeffrey K. Tong, Kenneth C. Anderson, Kerry Spear, Roger H. Pak, Janid Ali, Jebecka Hudak, Constantine S. Mitsiades, Emmanuel Normant, James Homer Wright, Melissa Pink, Louis Grenier, Jens Sydor, Michael Foley, Yun Gao, Junbiao Sang
Publikováno v:
Blood. 104:4922-4922
IPI-504 is a novel inhibitor of Hsp90 based on the geldanamycin pharmacophore. When placed in rat, monkey, and human blood, IPI-504 rapidly converts to the known and well-studied compound 17-allylamino-17-demethoxy-geldanamycin (17-AAG). 17-AAG is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd62aefb41f6324e4b5334429ce29775
https://doi.org/10.1182/blood.v104.11.4922.4922
https://doi.org/10.1182/blood.v104.11.4922.4922
Autor:
Jon Patterson
Publikováno v:
Social Thought and Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a556a2c2442d581f876065f0b6c001ee
https://doi.org/10.17161/str.1808.4748
https://doi.org/10.17161/str.1808.4748
Autor:
Jon Patterson
Publikováno v:
Social Thought and Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a5e1b5303462a631766ba5205431b27
https://doi.org/10.17161/str.1808.4731
https://doi.org/10.17161/str.1808.4731