Výsledky vyhledávání

Two-photon fluorescence lifetime imaging of intrinsic NADH in three-dimensional tumor models

Autor: Anh, Cong, Rafaela M L, Pimenta, Hong Bok, Lee, Venkatram, Mereddy, Jon, Holy, Ahmed A, Heikal

Publikováno v: Cytometry. Part A : the journal of the International Society for Analytical Cytology. 95(1)

Most studies using intrinsic NAD(P)H as biomarkers for energy metabolism and mitochondrial anomalies have been conducted in routine two-dimensional (2D) cell culture formats. Cellular metabolism and cell behavior, however, can be significantly differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8775a46cc26f5bf42d4775a2bccf0ffd
https://pubmed.ncbi.nlm.nih.gov/30343512

Zobrazit plný text záznamu

Mycobacterium lepraeinfection of human Schwann cells depends on selective host kinases and pathogen-modulated endocytic pathways

Autor: Lucineia Alves, Leila MendonÃ§a Lima, Elisa Silva Maeda, LaÃs Carvalho, Jon Holy, Euzenir Nunes Sarno, Maria Cristina Vidal Pessolani, Lucia P. Barker

Publikováno v: FEMS Microbiology Letters. 238:429-437

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6e1b2b0e24824ba93792fd0ed9ec1ff
https://doi.org/10.1111/j.1574-6968.2004.tb09786.x

Zobrazit plný text záznamu

Vital imaging of multicellular spheroids

Autor: Paulo J, Oliveira, Edward L, Perkins, Jon, Holy

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1075

Cell behavior is significantly different in two-dimensional and three-dimensional culture conditions, and a number of methods have been developed to establish and study three-dimensional cellular arrays in vitro. When grown under nonadherent conditio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0863c46fcaf901adb076f931df0501ff
https://pubmed.ncbi.nlm.nih.gov/24052355

Zobrazit plný text záznamu

Biologic activity of a dinuclear Pd(II)-spermine complex toward human breast cancer

Autor: Sónia M, Fiuza, Jon, Holy, Luis A E, Batista de Carvalho, Maria P M, Marques

Publikováno v: Chemical biologydrug design. 77(6)

A dinuclear palladium-based complex (Pd(2) -Spm) was synthesized and compared with cisplatin (cDDP) on two different human breast cancer cell lines (MCF-7 and MDA-MB-231) as well as toward an untransformed cell line (BJ fibroblasts). The results obta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0dab90e0a1001eeb14f88f2574d447fe
https://pubmed.ncbi.nlm.nih.gov/21371266

Zobrazit plný text záznamu

Mycobacterium leprae infection of human Schwann cells depends on selective host kinases and pathogen-modulated endocytic pathways

Autor: Lucineia, Alves, Leila, de Mendonça Lima, Elisa, da Silva Maeda, Laís, Carvalho, Jon, Holy, Euzenir Nunes, Sarno, Maria Cristina Vidal, Pessolani, Lucia P, Barker

Publikováno v: FEMS microbiology letters. 238(2)

Mycobacterium leprae, an obligate intracellular pathogen, shows a unique tropism for Schwann cells (SC). This leads to the peripheral neuropathy disorder observed in leprosy. In this study, we investigated signal transduction events and the intracell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d5efb370f03edcd07e1beaf0f0a1c224
https://pubmed.ncbi.nlm.nih.gov/15358430

Zobrazit plný text záznamu