Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Jon, Agirre"'
Autor:
Jordan S. Dialpuri, Haroldas Bagdonas, Lucy C. Schofield, Phuong Thao Pham, Lou Holland, Jon Agirre
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 931-939 (2024)
The remediation of the carbohydrate data of the Protein Data Bank (PDB) has brought numerous enhancements to the findability and interpretability of deposited glycan structures, yet crucial quality indicators are either missing or hard to find on the
Externí odkaz:
https://doaj.org/article/c76ce5f10712417281506b4c1f0948fc
Autor:
Isabel Pérez-Jover, Kristy Rochon, Di Hu, Mukesh Mahajan, Pooja Madan Mohan, Isaac Santos-Pérez, Julene Ormaetxea Gisasola, Juan Manuel Martinez Galvez, Jon Agirre, Xin Qi, Jason A. Mears, Anna V. Shnyrova, Rajesh Ramachandran
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The mechanochemical GTPase dynamin-related protein 1 (Drp1) catalyzes mitochondrial and peroxisomal fission, but the regulatory mechanisms remain ambiguous. Here we find that a conserved, intrinsically disordered, six-residue Short Linear Mo
Externí odkaz:
https://doaj.org/article/de04eb6b03704799b410f8586ef1b1f7
Autor:
Robbie P Joosten, Jon Agirre
Publikováno v:
PLoS Biology, Vol 20, Iss 5, p e3001673 (2022)
Accurate but protein-only AlphaFold models may show structural fingerprints of likely posttranslational modifications (PTMs). In this issue of PLOS Biology, Bludau and colleagues add a functional context to models by combining them with readily avail
Externí odkaz:
https://doaj.org/article/502357c34cb1482c803242c42f30ccc9
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 2523-2533 (2020)
The heterogeneity, mobility and complexity of glycans in glycoproteins have been, and currently remain, significant challenges in structural biology. These aspects present unique problems to the two most prolific techniques: X-ray crystallography and
Externí odkaz:
https://doaj.org/article/a6ef2e3f08f5473f804987f704709dc4
Autor:
Onno Akkermans, Céline Delloye-Bourgeois, Claudia Peregrina, Maria Carrasquero-Ordaz, Maria Kokolaki, Miguel Berbeira-Santana, Matthieu Chavent, Florie Reynaud, Ritu Raj, Jon Agirre, Metin Aksu, Eleanor S. White, Edward Lowe, Dounia Ben Amar, Sofia Zaballa, Jiandong Huo, Irene Pakos, Patrick T.N. McCubbin, Davide Comoletti, Raymond J. Owens, Carol V. Robinson, Valérie Castellani, Daniel del Toro, Elena Seiradake
Neural migration is a critical step during brain development that requires the interactions of cell-surface guidance receptors. Cancer cells often hijack these mechanisms to disseminate. Here, we reveal crystal structures of Uncoordinated-5 receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f639c2764fd0c039883a39c5c74777
https://doi.org/10.1016/j.cell.2022.09.025
https://doi.org/10.1016/j.cell.2022.09.025
Autor:
Eugene Krissinel, Andrey A. Lebedev, Ville Uski, Charles B. Ballard, Ronan M. Keegan, Oleg Kovalevskiy, Robert A. Nicholls, Navraj S. Pannu, Pavol Skubák, John Berrisford, Maria Fando, Bernhard Lohkamp, Marcin Wojdyr, Adam J. Simpkin, Jens M. H. Thomas, Christopher Oliver, Clemens Vonrhein, Grzegorz Chojnowski, Arnaud Basle, Andrew Purkiss, Michail N. Isupov, Stuart McNicholas, Edward Lowe, Josep Triviño, Kevin Cowtan, Jon Agirre, Daniel J. Rigden, Isabel Uson, Victor Lamzin, Ivo Tews, Gerard Bricogne, Andrew G. W. Leslie, David G. Brown
Nowadays, progress in the determination of three-dimensional macromolecular structures from diffraction images is achieved partly at the cost of increasing data volumes. This is due to the deployment of modern high-speed, high-resolution detectors, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70211be538eb43722afb9f6169aea790
https://eprints.soton.ac.uk/471374/
https://eprints.soton.ac.uk/471374/
Publikováno v:
Acta Crystallographica Section D Structural Biology. 78:1192-1193
Autor:
Pu Qian, Alastair T. Gardiner, Ivana Šímová, Katerina Naydenova, Tristan I. Croll, Philip J. Jackson, null Nupur, Miroslav Kloz, Petra Čubáková, Marek Kuzma, Yonghui Zeng, Pablo Castro-Hartmann, Bart van Knippenberg, Kenneth N. Goldie, David Kaftan, Pavel Hrouzek, Jan Hájek, Jon Agirre, C. Alistair Siebert, David Bína, Kasim Sader, Henning Stahlberg, Roman Sobotka, Christopher J. Russo, Tomáš Polívka, C. Neil Hunter, Michal Koblížek
Publikováno v:
Science Advances
Qian, P, Gardiner, A T, Šímová, I, Naydenova, K, Croll, T I, Jackson, P J, Nupur, Kloz, M, Čubáková, P, Kuzma, M, Zeng, Y, Castro-Hartmann, P, van Knippenberg, B, Goldie, K N, Kaftan, D, Hrouzek, P, Hájek, J, Agirre, J, Siebert, C A, Bína, D, Sader, K, Stahlberg, H, Sobotka, R, Russo, C J, Polívka, T, Hunter, C N & Koblížek, M 2022, ' 2.4-Å structure of the double-ring Gemmatimonas phototrophica photosystem ', Science Advances, vol. 8, no. 7, eabk3139 . https://doi.org/10.1126/sciadv.abk3139
Qian, P, Gardiner, A T, Šímová, I, Naydenova, K, Croll, T I, Jackson, P J, Nupur, Kloz, M, Čubáková, P, Kuzma, M, Zeng, Y, Castro-Hartmann, P, van Knippenberg, B, Goldie, K N, Kaftan, D, Hrouzek, P, Hájek, J, Agirre, J, Siebert, C A, Bína, D, Sader, K, Stahlberg, H, Sobotka, R, Russo, C J, Polívka, T, Hunter, C N & Koblížek, M 2022, ' 2.4-Å structure of the double-ring Gemmatimonas phototrophica photosystem ', Science Advances, vol. 8, no. 7, eabk3139 . https://doi.org/10.1126/sciadv.abk3139
Phototrophic Gemmatimonadetes evolved the ability to use solar energy following horizontal transfer of photosynthesis-related genes from an ancient phototrophic proteobacterium. The electron cryo-microscopy structure of the Gemmatimonas phototrophica
Autor:
William Rochira, Jon Agirre
Publikováno v:
Protein Science : A Publication of the Protein Society
Iris validation is a Python package created to represent comprehensive per‐residue validation metrics for entire protein chains in a compact, readable and interactive view. These metrics can either be calculated by Iris, or by a third‐party progr
Publikováno v:
Nature structuralmolecular biology. 28(11)