Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jomon Joseph"'
Publikováno v:
Nucleus, Vol 13, Iss 1, Pp 154-169 (2022)
Dominant missense mutations in RanBP2/Nup358 cause Acute Necrotizing Encephalopathy (ANE), a pediatric disease where seemingly healthy individuals develop a cytokine storm that is restricted to the central nervous system in response to viral infectio
Externí odkaz:
https://doaj.org/article/1c000b1d2bc4405ebf7a990e65168888
Publikováno v:
Biology Open, Vol 2, Iss 11, Pp 1270-1278 (2013)
Summary Par polarity complex, consisting of Par3, Par6, and aPKC, plays a conserved role in the establishment and maintenance of polarization in diverse cellular contexts. Recent reports suggest that Dishevelled (Dvl), a cytoplasmic mediator of Wnt s
Externí odkaz:
https://doaj.org/article/33ce03c0c9614d2c91464eef336359ea
Autor:
Pabitra K. Sahoo, Prayag Murawala, Pravin T. Sawale, Manas R. Sahoo, Mukesh M. Tripathi, Swati R. Gaikwad, Vasudevan Seshadri, Jomon Joseph
Publikováno v:
Biology Open, Vol 1, Iss 2, Pp 109-119 (2012)
Summary Cells often respond to diverse environmental stresses by inducing stress granules (SGs) as an adaptive mechanism. SGs are generally assembled as a result of aggregation of mRNAs stalled in a translational pre-initiation complex, mediated by a
Externí odkaz:
https://doaj.org/article/d8f09c24894a424089847c8735275fb4
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125506 (2015)
Ran, a member of the Ras-GTPase superfamily, has a well-established role in regulating the transport of macromolecules across the nuclear envelope (NE). Ran has also been implicated in mitosis, cell cycle progression, and NE formation. Over-expressio
Externí odkaz:
https://doaj.org/article/346c29d100574d3bbefecff6a4ab56db
Autor:
Amaresh C Panda, Itishri Sahu, Shardul D Kulkarni, Jennifer L Martindale, Kotb Abdelmohsen, Arya Vindu, Jomon Joseph, Myriam Gorospe, Vasudevan Seshadri
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101084 (2014)
The 5' and the 3' untranslated regions (UTR) of the insulin genes are very well conserved across species. Although microRNAs (miRNAs) are known to regulate insulin secretion process, direct regulation of insulin biosynthesis by miRNA has not been rep
Externí odkaz:
https://doaj.org/article/5c7cfb7fbb754cd6a331bde6b05a6c6d
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83790 (2013)
Here we have identified and characterized a devastating virus capable of inducing yellow mosaic on the leaves of Patchouli [Pogostemon cablin (Blanco) Benth]. The diagnostic tools used were host range, transmission studies, cytopathology, electron mi
Externí odkaz:
https://doaj.org/article/f809abbff0224641ba9f3c06531b3e6e
Autor:
Dimple Notani, Kamalvishnu P Gottimukkala, Ranveer S Jayani, Amita S Limaye, Madhujit V Damle, Sameet Mehta, Prabhat Kumar Purbey, Jomon Joseph, Sanjeev Galande
Publikováno v:
PLoS Biology, Vol 8, Iss 1, p e1000296 (2010)
In vertebrates, the conserved Wnt signalling cascade promotes the stabilization and nuclear accumulation of beta-catenin, which then associates with the lymphoid enhancer factor/T cell factor proteins (LEF/TCFs) to activate target genes. Wnt/beta -ca
Externí odkaz:
https://doaj.org/article/04e2bad73d664ebd92c93af07dc38d0a
Autor:
Sakalya Chavan, Deepak Khuperkar, Akshay Lonare, Swagatika Panigrahi, Jayesh Bellare, Srikanth Rapole, Vasudevan Seshadri, Jomon Joseph
Publikováno v:
Cellular and Molecular Life Sciences. 79
Small extracellular vesicle (sEV)-mediated intercellular communication regulates multiple aspects of growth and development in multicellular organisms. However, the mechanism underlying cargo recruitment into sEVs is currently unclear. We show that t
Publikováno v:
Journal of cell science. 135(4)
Nuclear export of mRNAs is a critical regulatory step in eukaryotic gene expression. The mRNA transcript undergoes extensive processing, and is loaded with a set of RNA-binding proteins (RBPs) to form export-competent messenger ribonucleoprotein part
Autor:
Rimpi Saikia, Jomon Joseph
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 99(11)
Autophagy is a well-known cell-survival strategy orchestrated by a conserved set of proteins. It equips the cells with mechanisms to attain homeostasis during unfavorable conditions such as stress by breaking down the cellular components and reusing