Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jolie K. Kwee"'
Publikováno v:
Revista Brasileira de Cancerologia, Vol 30, Iss 4 (2023)
Os autores estudaram a inibição da atividade de xantina desidrogenase (XD) do soro de ratas pelo acetado de cobre (AcCu). Verificaram também a relação entre a atividade XD e a degeneração hepática e carcinogênese pela D-L-etionina. Experiên
Externí odkaz:
https://doaj.org/article/8c491476630348e4ae90f5810d5ea97c
Publikováno v:
Redox report : communications in free radical research. 1(4)
Nitric oxide reacts with superoxide to produce peroxynitrite which has been reported to be highly microbicidal to Trypanosoma cruzi in phosphate buffer but ineffective against Leishmania major in culture medium. This contradiction and the potential i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5ee1a0b23114a59dfd3f1cae9a482f
https://pubmed.ncbi.nlm.nih.gov/27405713
https://pubmed.ncbi.nlm.nih.gov/27405713
Autor:
Geraldo Barroso Cavalcanti, Karina Lani Silva, Flavia da Cunha Vasconcelos, Raquel Ciuvalschi Maia, Vivian M. Rumjanek, Ernesto de Meis, Jolie K. Kwee
Publikováno v:
Leukemia Research. 31:445-454
The expression and activity of P-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP1) were analyzed in 178 leukemia samples. Rhodamine-123 (Rho-123) and DiOC2 were used as substrate to evaluate efflux pump activity. Chronic myeloid l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a1662dd4a1963b0030e866b2964482
https://doi.org/10.1016/j.leukres.2006.07.016
https://doi.org/10.1016/j.leukres.2006.07.016
Autor:
Ana Carolina dos Santos Ferreira, Carlos A. M. Fraga, Jolie K. Kwee, Guilherme Álvaro Ferreira-Silva, Marisa Ionta, Daniel Alencar Rodrigues, Renan Amphilophio Fernandes, Carlos Mauricio R. Sant'Anna
Publikováno v:
Journal of medicinal chemistry. 59(2)
This manuscript describes a novel class of N-acylhydrazone (NAH) derivatives that act as histone deacetylase (HDAC) 6/8 dual inhibitors and were designed from the structure of trichostatin A (1). Para-substituted phenyl-hydroxamic acids presented a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2747d97953a76315426df6964ca4f4cb
https://pubmed.ncbi.nlm.nih.gov/26705137
https://pubmed.ncbi.nlm.nih.gov/26705137
Autor:
Raquel Ciuvalschi Maia, Jolie K. Kwee, Flavia da Cunha Vasconcelos, Karina Lani Silva, Luis Fernando Marques-Santos
Publikováno v:
Leukemia research. 27(3)
CPT-11 is a topoisomerase I (Topo I) inhibitor which was initially described as active in multi-drug resistance (MDR) tumors. The MDR phenomenon is characterized by the overexpression of efflux pumps which are able to extrude a range of drugs non-rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3296518ab8c7bce24022b2ef6e5e4b15
https://pubmed.ncbi.nlm.nih.gov/12537977
https://pubmed.ncbi.nlm.nih.gov/12537977
Publikováno v:
Chemico-biological interactions. 116(1-2)
The ability of C8-substituted guanine (Gua) ribonucleosides to induce B cell proliferation has been well documented in the literature. These compounds are analogues of adducts formed from free radical attack on ribonucleosides and RNA. Here we examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8193ba8a78cb0178ce232625cee109
https://pubmed.ncbi.nlm.nih.gov/9877201
https://pubmed.ncbi.nlm.nih.gov/9877201
Publikováno v:
Acta tropica. 70(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e809d06cfcd122c0b103d9bcee925e52
https://pubmed.ncbi.nlm.nih.gov/9707370
https://pubmed.ncbi.nlm.nih.gov/9707370
Autor:
Jolie K. Kwee, Ana Carolina S. Ferreira, Flavia da Cunha Vasconcelos, Diogo Gomes Luque, Raquel Ciuvalschi Maia
Publikováno v:
Blood. 106:4890-4890
Imatinib (imatinib mesylate: Novartis Pharmaceuticals, Basel, Switzerland) is a well-known selective inhibitor of BCR-ABL tyrosine kinase activity, a hallmark enzyme in the pathogenesis of chronic myeloid leukemia (CML). Resistance to imatinib in CML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d24161496514b3114b29fcd21364d32
https://doi.org/10.1182/blood.v106.11.4890.4890
https://doi.org/10.1182/blood.v106.11.4890.4890