Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jolicia F. Gauuan"'
Publikováno v:
Synlett. 2012:247-250
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46263fc5cf43a31f2cca138975cd72d3
https://doi.org/10.1055/s-0031-1290129
https://doi.org/10.1055/s-0031-1290129
Autor:
Ying Zhai, Ellen Xia, Lei Chen, Bandarpalle B. Shankar, Qingbei Zeng, Anilkumar G. Nair, Sony Agrawal, Ronald N. Buckle, Guowei Zhou, Kannan P. Naicker, John P. Caldwell, Ling Tong, Yueheng Jiang, Stuart B. Rosenblum, Wensheng Yu, Kerry Keertikar, Haiqun Tang, Seong Heon Kim, Rong Liu, De-Yi Yang, Paul Ingravallo, Gregory Scott Martin, Samuel A. Vellekoop, Melissa L. Allard, Christian L. Holst, Michael P. Dwyer, Amin A. Nomeir, Robert Mazzola, Polivina Jolicia F Gauuan, Joseph A. Kozlowski, Oleg Selyutin, Rong Kong
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(5)
HCV NS5A inhibitors have shown impressive in vitro potency profiles in HCV replicon assays thus making them attractive components for inclusion in an all oral fixed dose combination treatment regimen. Herein we describe the research efforts that led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85586f1ce259c9e4c3146d6078489ecd
https://pubmed.ncbi.nlm.nih.gov/26850003
https://pubmed.ncbi.nlm.nih.gov/26850003
Autor:
Matthew Robert Johnson, Rajesh A. Shenoy, Van-Duc Le, Jolicia F. Gauuan, Howard Roark, James M. Hamby, Cheng Guo, Peter R. Guzzo, Michael Stier, John E. Mangette
Publikováno v:
Synthetic Communications. 41:2769-2793
As part of a medicinal chemistry collaboration, a number of novel bi- and tricyclic α-amino acids were prepared through various routes and characterized by 1H nuclear Overhauser effect difference experiments. The syntheses provide a number of routes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b97d40299e3775108835562d3710e7f
https://doi.org/10.1080/00397911.2010.515354
https://doi.org/10.1080/00397911.2010.515354
Publikováno v:
The Journal of Organic Chemistry. 74:9546-9549
The asymmetric total synthesis of (+)-crassalactone D (4), a naturally occurring antitumor agent, has been achieved by employing an oxidative spirocyclization of furan 11 as the key step. Two close analogues, 7-epi-crassalactone D (14) and 5-epi-7-ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3473a0a51b888b94e5a203ebd001f4e
https://doi.org/10.1021/jo902055b
https://doi.org/10.1021/jo902055b
Autor:
Paul E. Morin, Pancras C. Wong, Darren Orton, Wei Han, Patrick Y.S. Lam, Yun-Long Li, C.-H. Chang, Joseph M. Luettgen, Ruth R. Wexler, James R. Corte, Robert M. Knabb, Mark Hadden, Donald J. P. Pinto, Jolicia F. Gauuan, Zilun Hu, Xiang-Jun Jiang, Tianan Fang, Kan He, Daniel L. Cheney, Alan R. Rendina
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:2845-2849
Introduction of the phenyl piperidinone and phenyl pyridinone P4 moieties in the anthranilamide scaffold led to potent, selective, and orally bioavailable inhibitors of factor Xa. Anthranilamide 28 displayed comparable efficacy to apixaban in the rab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f0e123723f0355168a127b067954db
https://doi.org/10.1016/j.bmcl.2008.03.092
https://doi.org/10.1016/j.bmcl.2008.03.092
Autor:
Stephen B Bocckino, Brian J. Day, Michael P. Trova, Livia Gregor-Boros, Polivina Jolicia F Gauuan, James D. Crapo
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:3013-3021
Carboxylic ester and amide-substituted analogues of [5,10,15,20-tetrakis(4-carboxyphenyl)-porphyrinato]manganese(III) chloride (MnTBAP) were synthesized and assayed as potential superoxide dismutase (SOD) mimetics. The tetraester analogues 4a and 4b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3055c38a4fe72833315ab59c97bd5b4e
https://doi.org/10.1016/s0968-0896(02)00153-0
https://doi.org/10.1016/s0968-0896(02)00153-0
Publikováno v:
ChemInform. 43
A novel protocol is presented for the synthesis of benzimidazoles (III) which can be extended to benzoxazoles by use of 2-aminophenol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d58d7d76b8d2baca2d0ce1854725e2
https://doi.org/10.1002/chin.201220123
https://doi.org/10.1002/chin.201220123
Autor:
Jolicia F. Gauuan, Frank M. Hauser
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b686559cd41f1bbfb58233c3eb7c08fc
https://doi.org/10.1002/chin.199949201
https://doi.org/10.1002/chin.199949201
Autor:
Brian J. Day, Polivina Jolicia F Gauuan, Stephen M Bubb, Michael P. Trova, Stephen B Bocckino, Anthony D. Pechulis, James D. Crapo
Publikováno v:
Bioorganicmedicinal chemistry. 11(13)
Novel glyoxylate- and glyoxamide-derived metalloporphyrins 26-58 were synthesized and evaluated as potential superoxide dismutase (SOD) mimetics. Relative to previously studied MnTBAP analogues, the glyoxylate-derived metalloporphyrins 32, 39, and 54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd65726cd83d879ec7254a261b7be850
https://pubmed.ncbi.nlm.nih.gov/12788343
https://pubmed.ncbi.nlm.nih.gov/12788343
Publikováno v:
Organic letters. 1(4)
[formula: see text] A regiospecific total synthesis of (+/-)-biphyscion (1) is described. A novel aspect of the plan was construction of the bianthraquinone ring system from a biphenyl intermediate through the use of a one-pot, double isobenzofuranon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fdeeb533b74f1be9d6ee1ebc59a278
https://pubmed.ncbi.nlm.nih.gov/10823198
https://pubmed.ncbi.nlm.nih.gov/10823198