Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jolene Shorr"'
Autor:
Adil Daud, Ezra Cohen, Matthew Reilley, Siwen Hu-Lieskovan, Shubham Pant, Raphael Clynes, Roger Cohen, Anthony Shields, Mark Stein, Alain Mita, Bartosz Chmielowski, Yana Najjar, Elaine Shum, Joaquina Baranda, R Donald Harvey, Catherine Fleener, Ying Ding, Sowmya Chollate, Jolene Shorr, Barbara Hickingbottom, Lei Bao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/6a7db806111f4ca8b46be50a0a23239a
Autor:
Adil Daud, Rom Leidner, Ezra Cohen, Matthew Reilley, Siwen Hu-Lieskovan, Raphael Clynes, Roger Cohen, John Thompson, Mark Stein, Alain Mita, Bartosz Chmielowski, Yana Najjar, Elaine Shum, R Donald Harvey, Catherine Fleener, Ying Ding, Sowmya Chollate, Hector Avina, Jolene Shorr, Barbara Hickingbottom
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/7dc52d27a41d43ff9ad5408e51584f5b
Autor:
Mark Stein, Oscar Goodman, Tanya Dorff, Vivek Narayan, Jose Avitia, Rana McKay, Luke Nordquist, Matthew Rettig, Michael Schweizer, Roby Thomas, Michael Silverman, Li Yao, Raphael Clynes, Jolene Shorr
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1531c4a627553cfd630df4d9d4b340b
https://doi.org/10.1136/jitc-2022-sitc2022.0668
https://doi.org/10.1136/jitc-2022-sitc2022.0668
Autor:
Catherine Fleener, Raphael Clynes, Ezra E.W. Cohen, Bartosz Chmielowski, Shubham Pant, Ying Ding, Joaquina Baranda, Barbara Hickingbottom, Rom Leidner, Yana G. Najjar, Adil Daud, Lei Bao, Roger B. Cohen, Siwen Hu-Lieskovan, Anthony F. Shields, Alain C. Mita, John A. Thompson, Elaine Shum, Sowmya Chollate, Matthew J. Reilley, Mark N. Stein, R. Donald Harvey, Jolene Shorr
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundXmAb20717 is a humanized bispecific monoclonal antibody that simultaneously targets PD-1 and CTLA-4. We report updated data on patients treated at the recommended expansion dose from an ongoing, multicenter, Phase 1, dose-escalation and -ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f16c58150b3f9e4ad7eb77e894ec73
https://doaj.org/article/6a7db806111f4ca8b46be50a0a23239a
https://doaj.org/article/6a7db806111f4ca8b46be50a0a23239a
Autor:
Rom Leidner, Ezra E.W. Cohen, Elaine Shum, Shubham Pant, Siwen Hu-Lieskovan, Yana G. Najjar, Raphael Clynes, Jolene Shorr, Alain C. Mita, R. Donald Harvey, Sowmya Chollate, Ying Ding, Adil Daud, Matthew J. Reilley, Anthony F. Shields, John A. Thompson, Mark N. Stein, Joaquina Baranda, Roger B. Cohen, Hector Avina, Barbara Hickingbottom, Bartosz Chmielowski, Catherine Fleener
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background XmAb20717 is a humanized bispecific monoclonal antibody that simultaneously targets PD-1 and CTLA-4. We report preliminary data from an ongoing, multicenter, Phase 1 study investigating the safety/tolerability, pharmacokinetics/pharmacodyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3aacb6415045ec4c7258c5802fa574
https://doi.org/10.1136/jitc-2020-sitc2020.0407
https://doi.org/10.1136/jitc-2020-sitc2020.0407
Autor:
Jordi Rodon Ahnert, Harry E. Gruber, Maria Rodriguez-Aguirre, Douglas J. Jolly, Cornelia Bentley, Peder Horner, William P. Accomando, Jolene Shorr, Arthur Donahue, Amber Thomassen, Thian Kheoh, Sharon Yavrom, Jaime R. Merchan, Gerald Steven Falchook, Derek Ostertag, Daniel J. Hogan, Shree Venkat
Publikováno v:
Journal of Clinical Oncology. 38:186-186
186 Background: Toca 511 (vocimagene amiretrorepvec) is a cancer-selective, retroviral replicating vector encoding yeast cytosine deaminase that converts 5-fluorocytosine (5-FC) into 5-fluorouracil in the tumor microenvironment (TME). In animal model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be92c5c25be54afc018921a2d8e4e4d1
https://doi.org/10.1200/jco.2020.38.4_suppl.186
https://doi.org/10.1200/jco.2020.38.4_suppl.186
Autor:
Timothy F. Cloughesy, Michael A. Vogelbaum, Tobias Walbert, Douglas J. Jolly, Linda M. Liau, Jolene Shorr, Leah Mitchell, Derek Ostertag, Maria Rodriguez-Aquirre, Harry E. Gruber, Tom Mikkelsen, Steven N. Kalkanis, Daniela A. Bota
Publikováno v:
Neuro-Oncology, vol 19, iss suppl_6
Neuro-oncology, vol 19, iss Suppl 6
Neuro-oncology, vol 19, iss Suppl 6
Toca 511 (vocimagene amiretroprepvec) is an investigational, conditionally lytic, retroviral replicating vector that encodes an optimized yeast cytosine deaminase (CD) gene. The CD gene converts the prodrug, Toca FC (investigational, extended-release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a764b6a16b584e8d1cfc6299998308
https://escholarship.org/uc/item/2c02979m
https://escholarship.org/uc/item/2c02979m
Autor:
Jaime R. Merchan, Douglas J. Jolly, Joyce M. Slingerland, Shuichi Kamijima, Kei Hiraoka, Angela M. Richardson, Noriyuki Kasahara, Jolene Shorr, Sara Collins, Akihito Inagaki, Harry E. Gruber
Toca 511, a clinical-stage retroviral replicating vector (RRV) encoding an optimized yeast cytosine deaminase (CD) prodrug activator gene, in combination with Toca FC (extended-release 5-fluorocytosine (5-FC)), is designed to produce 5-FU which kills
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a156a0c3d60ec334fc80772dc5e8657
https://europepmc.org/articles/PMC5692653/
https://europepmc.org/articles/PMC5692653/
Autor:
Arthur Donahue, Gerald Steven Falchook, Peder Horner, Douglas J. Jolly, Dalissa Tijera, Jordi Rodon, Harry E. Gruber, Derek Ostertag, Thian Kheoh, Jaime R. Merchan, Shree Venkat, Jolene Shorr
Publikováno v:
Cancer Immunology Research. 7:A018-A018
Toca 511 (vocimagene amiretrorepvec) is an investigational, conditionally lytic, retroviral replicating vector that selectively infects cancer cells due to cell division requirements for virus integration into the genome, and defects in innate and ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6aa88c079446a55941a426e7447c4f6
https://doi.org/10.1158/2326-6074.cricimteatiaacr18-a018
https://doi.org/10.1158/2326-6074.cricimteatiaacr18-a018
Autor:
Maria Rodriguez-Aguirre, Harry E. Gruber, Doug J. Jolly, Leah Mitchell, Michael A. Vogelbaum, Timothy F. Cloughesy, Danilella Bota, Steven N. Kalkanis, Tom Mikkelsen, Tobias Walbert, Linda M. Liau, Derek Ostertag, Jolene Shorr
Publikováno v:
Neuro-Oncology. 19:vi265-vi266
Toca 511 (vocimagene amiretroprepvec) is an investigational, conditionally lytic, retroviral replicating vector that encodes an optimized yeast cytosine deaminase (CD) gene. The CD gene converts the prodrug, Toca FC (investigational, extended-release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c4746699d793c45376cb6e6ed04202
https://doi.org/10.1093/neuonc/nox168.1089
https://doi.org/10.1093/neuonc/nox168.1089