Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jolene S. Ranek"'
Autor:
Jolene S. Ranek, Wayne Stallaert, J. Justin Milner, Margaret Redick, Samuel C. Wolff, Adriana S. Beltran, Natalie Stanley, Jeremy E. Purvis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-26 (2024)
Abstract Single-cell technologies can measure the expression of thousands of molecular features in individual cells undergoing dynamic biological processes. While examining cells along a computationally-ordered pseudotime trajectory can reveal how ch
Externí odkaz:
https://doaj.org/article/61fd6325be8549fe80717d1d5f3b6136
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-32 (2022)
Abstract Background Current methods for analyzing single-cell datasets have relied primarily on static gene expression measurements to characterize the molecular state of individual cells. However, capturing temporal changes in cell state is crucial
Externí odkaz:
https://doaj.org/article/9634196da679468791340653b9995663
Autor:
Joseph Burclaff, R. Jarrett Bliton, Keith A. Breau, Meryem T. Ok, Ismael Gomez-Martinez, Jolene S. Ranek, Aadra P. Bhatt, Jeremy E. Purvis, John T. Woosley, Scott T. Magness
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1554-1589 (2022)
Background & Aims: Single-cell transcriptomics offer unprecedented resolution of tissue function at the cellular level, yet studies analyzing healthy adult human small intestine and colon are sparse. Here, we present single-cell transcriptomics cover
Externí odkaz:
https://doaj.org/article/a1fb61ec98544b24bf91beebecf41474
Cell cycle plasticity underlies fractional resistance to palbociclib in ER+/HER2- breast tumor cells
Autor:
Tarek M. Zikry, Samuel C. Wolff, Jolene S. Ranek, Harris Davis, Ander Naugle, Austin A. Whitman, Michael R. Kosorok, Philip M. Spanheimer, Jeremy E. Purvis
The CDK4/6 inhibitor palbociclib blocks cell cycle progression in ER+/HER2- breast tumor cells. Although these drugs have significantly improved patient outcomes in metastatic breast cancers, a small percentage of tumor cells continues to divide in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d303f7359c81fae55b36fa940beacd36
https://doi.org/10.1101/2023.05.22.541831
https://doi.org/10.1101/2023.05.22.541831
Single-cell technologies can readily measure the expression of thousands of molecular features from individual cells undergoing dynamic biological processes, such as cellular differentiation, immune response, and disease progression. While examining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c5d8b189a34df24d046aba6a54333e2
https://doi.org/10.1101/2023.05.09.540043
https://doi.org/10.1101/2023.05.09.540043
Autor:
Keith A. Breau, Ismael Gomez-Martinez, Jolene S. Ranek, Joseph Burclaff, Scott T. Magness, Aadra P. Bhatt, Jeremy E. Purvis, Meryem T. Ok, R. Jarrett Bliton, John T. Woosley
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology. 13:1554-1589
Background and AimsSingle-cell transcriptomics offer unprecedented resolution of tissue function at the cellular level, yet studies analyzing healthy adult human small intestine and colon are sparse. Here, we present single-cell transcriptomics cover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9386c3e8f1019b190131aea0e7f423c
https://doi.org/10.1016/j.jcmgh.2022.02.007
https://doi.org/10.1016/j.jcmgh.2022.02.007
Background Current methods for analyzing single-cell datasets have relied primarily on static gene expression measurements to characterize the molecular state of individual cells. However, capturing temporal changes in cell state is crucial for the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f37eb82151ef733a4da07401959fdc0
https://doi.org/10.1101/2022.03.01.482381
https://doi.org/10.1101/2022.03.01.482381
Autor:
Catherine L. Young, Jeremy E. Purvis, Wayne Stallaert, Katarzyna M. Kedziora, Sovanny R. Taylor, Colin D. Taylor, Jolene S. Ranek, Holly K. Sobon, Tarek M. Zikry, Jeanette Gowen Cook
Publikováno v:
Cell Syst
The human cell cycle is conventionally depicted as a five-phase model consisting of four proliferative phases (G1, S, G2, M) and a single state of arrest (G0). However, recent studies show that individual cells can take different paths through the ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cfa3aa457df579575ae84cf1ee9261
https://doi.org/10.1101/2021.02.11.430845
https://doi.org/10.1101/2021.02.11.430845
Autor:
Joseph Burclaff, Jarrett Bliton, Keith A. Breau, Meryem T. Ok, Ismael Gomez Martinez, Jolene S. Ranek, Aadra Bhatt, Jeremy E. Purvis, John T. Woosley, Scott Magness
Publikováno v:
Gastroenterology. 162:S-205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2cfd05a5780f0d565fb039bec73d824
https://doi.org/10.1016/s0016-5085(22)60494-3
https://doi.org/10.1016/s0016-5085(22)60494-3