Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jolene Ooi"'
Autor:
Xiaohong Xu, Yilin Tay, Bernice Sim, Su-In Yoon, Yihui Huang, Jolene Ooi, Kagistia Hana Utami, Amin Ziaei, Bryan Ng, Carola Radulescu, Donovan Low, Alvin Yu Jin Ng, Marie Loh, Byrappa Venkatesh, Florent Ginhoux, George J. Augustine, Mahmoud A. Pouladi
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 619-633 (2017)
Huntington disease (HD) is a dominant neurodegenerative disorder caused by a CAG repeat expansion in HTT. Here we report correction of HD human induced pluripotent stem cells (hiPSCs) using a CRISPR-Cas9 and piggyBac transposon-based approach. We sho
Externí odkaz:
https://doaj.org/article/4f3f159daf3f4a9482f774ea8af66b7b
Autor:
Jolene Ooi, Pentao Liu
Publikováno v:
Cell Regeneration, Vol 1, Iss 1 (2012)
Pluripotency is depicted by a self-renewing state that can competently differentiate to form the three germ layers. Different stages of early murine development can be captured on a petri dish, delineating a spectrum of pluripotent states, ranging fr
Externí odkaz:
https://doaj.org/article/030b13b64580464fba0b389a89ccdbce
Publikováno v:
Journal of medical imaging and radiation sciences. 53(3)
Radiographers provide mobile radiography services for patients who are critically ill as well as patients isolated due to highly infectious diseases such as COVID-19. The pandemic has caused the demand for mobile radiography to increase. This study a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d50bc6d7e4f43c028238847e7b693b
https://pubmed.ncbi.nlm.nih.gov/35872003
https://pubmed.ncbi.nlm.nih.gov/35872003
Autor:
Nicholas S. Caron, William Casazza, Sara Mostafavi, Galen E.B. Wright, Mahmoud A. Pouladi, Jolene Ooi, Xiaohong Xu, Michael R. Hayden, Colin J. D. Ross, Lorenzo Casal, Bernard Ng
Publikováno v:
Human Molecular Genetics
Huntington disease (HD) is a neurodegenerative disorder that is caused by a CAG repeat expansion in HTT. The length of this repeat, however, only explains a proportion of the variability in age of onset in patients. Genome-wide association studies ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e1708862a1779b6ffb575325092366
https://doi.org/10.1093/hmg/ddaa184
https://doi.org/10.1093/hmg/ddaa184
Publikováno v:
Journal of Medical Imaging and Radiation Sciences. 53:S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba94a55f0c889c736a4f23c31a74898c
https://doi.org/10.1016/j.jmir.2022.10.030
https://doi.org/10.1016/j.jmir.2022.10.030
Autor:
Florent Ginhoux, Xiaohong Xu, Yihui Huang, Mahmoud A. Pouladi, Jolene Ooi, Marie Loh, Donovan Low, Byrappa Venkatesh, Amin Ziaei, Yilin Tay, Carola I. Radulescu, Su-In Yoon, Bernice Sim, George J. Augustine, Bryan Tsong-Jye Ng, Kagistia Hana Utami, Alvin Yu Jin Ng
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 619-633 (2017)
Stem Cell Reports
Stem Cell Reports
Summary Huntington disease (HD) is a dominant neurodegenerative disorder caused by a CAG repeat expansion in HTT. Here we report correction of HD human induced pluripotent stem cells (hiPSCs) using a CRISPR-Cas9 and piggyBac transposon-based approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30373a67082f8f69937e4fae04f4651a
https://doi.org/10.1016/j.stemcr.2017.01.022
https://doi.org/10.1016/j.stemcr.2017.01.022
Autor:
Juergen A. Knoblich, Dong Shin Park, Florent Ginhoux, Shiming Ma, Sarah R. Langley, Kagistia Hana Utami, Chit Fang Cheok, Magdalena Renner, Obed Akwasi Aning, Jinqiu Zhang, Enrico Petretto, Mahmoud A. Pouladi, Jolene Ooi
Huntington disease (HD) manifests in both adult and juvenile forms. Mutant HTT gene carriers are thought to undergo normal brain development followed by a degenerative phase, resulting in progressive clinical manifestations. However, recent studies i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af3705fa5830833e1f74dd20d431199
https://doi.org/10.1101/850586
https://doi.org/10.1101/850586
Autor:
Michael R. Hayden, Nicholas S. Caron, Bernard Ng, Colin J. D. Ross, Lorenzo Casal, Mahmoud A. Pouladi, Sara Mostafavi, Galen E.B. Wright, Jolene Ooi, Xiaohong Xu
Huntington disease (HD) is a neurodegenerative disorder that is caused by a CAG repeat expansion in the HTT gene. In an attempt to identify genomic modifiers that contribute towards the age of onset of HD, we performed a transcriptome wide associatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a524016d413ea801947330120b582b
https://doi.org/10.1101/699033
https://doi.org/10.1101/699033
Autor:
Enrico Petretto, Obed Akwasi Aning, Jinqiu Zhang, Juergen A. Knoblich, Sarah R. Langley, Chit Fang Cheok, Mahmoud A. Pouladi, Jolene Ooi, Magdalena Renner
Publikováno v:
Pathogenic mechanisms.
Huntington disease (HD) manifests in both adult and juvenile forms. A widely accepted view posits that mutant HTT gene carriers undergo normal brain development followed some years later by a degenerative phase that ultimately results in progressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae2401310b61c841d60a831c1b7ef6a5
https://doi.org/10.1136/jnnp-2018-ehdn.46
https://doi.org/10.1136/jnnp-2018-ehdn.46
Publikováno v:
Stem Cells (Dayton, Ohio)
We previously demonstrated that coexpressing retinoic acid (RA) receptor gamma and liver receptor homolog-1 (LRH1 or NR5A2) with OCT4, MYC, KLF4, and SOX2 (4F) rapidly reprograms mouse embryonic fibroblast cells (MEFs) into induced pluripotent stem c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6732280c8c2e2283d7ab2813b13ff1
https://doi.org/10.1002/stem.1926
https://doi.org/10.1002/stem.1926