Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jolanta Fertala"'
Autor:
Andrzej Steplewski, Jolanta Fertala, Lan Cheng, Mark L. Wang, Michael Rivlin, Pedro Beredjiklian, Andrzej Fertala
Publikováno v:
Gels, Vol 9, Iss 12, p 971 (2023)
Excessive posttraumatic scarring in orthopedic tissues, such as joint capsules, ligaments, tendons, muscles, and peripheral nerves, presents a significant medical problem, resulting in pain, restricted joint mobility, and impaired musculoskeletal fun
Externí odkaz:
https://doaj.org/article/8b50bcc5bc314e0d8792833d10520fee
Publikováno v:
Heliyon, Vol 9, Iss 4, Pp e15368- (2023)
Purpose: This study aimed to evaluate the utility of a rationally engineered antibody that directly blocks collagen fibrillogenesis to reduce scar tissue formation associated with subconjunctival glaucoma surgery. Material and methods: Fourteen eyes
Externí odkaz:
https://doaj.org/article/9dca0d1a4b0b495c93f6683df2321355
Autor:
Benjamin A. Hendy, Jolanta Fertala, Thema Nicholson, Joseph A. Abboud, Surena Namdari, Andrzej Fertala
Publikováno v:
Health Science Reports, Vol 6, Iss 2, Pp n/a-n/a (2023)
Abstract Background and Aims Arthrofibrosis is a severe scarring condition characterized by joint stiffness and pain. Fundamental to developing arthrofibrotic scars is the accelerated production of procollagen I, a precursor of collagen I molecules t
Externí odkaz:
https://doaj.org/article/b3164917d4834750befbfc94240a23b6
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13438 (2023)
Highly organized collagen fibrils interlacing with proteoglycans form the crucial architecture of the cornea and facilitate its transparency. Corneal scarring from accidental injury, surgery, or infection alters this highly organized tissue, causing
Externí odkaz:
https://doaj.org/article/248bc916d3ff448a87cdfa941119d5cc
Autor:
Jolanta Fertala, Mark L. Wang, Michael Rivlin, Pedro K. Beredjiklian, Joseph Abboud, William V. Arnold, Andrzej Fertala
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 758 (2023)
Excessive scar formation is a hallmark of localized and systemic fibrotic disorders. Despite extensive studies to define valid anti-fibrotic targets and develop effective therapeutics, progressive fibrosis remains a significant medical problem. Regar
Externí odkaz:
https://doaj.org/article/0b39b2f3cf4140e3b8a72e5e918bd6c5
Autor:
Andrzej Steplewski, Jolanta Fertala, Ryan Tomlinson, Kevth’er Hoxha, Lin Han, Ocean Thakar, Jason Klein, Joseph Abboud, Andrzej Fertala
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 14, Iss 1, Pp 1-13 (2019)
Abstract Background Increased tendon pain and tendon damage is a significant complication related to hyperlipidemia. Unlike the well-established pathogenesis associated with increased serum concentrations of total cholesterol, triglycerides, and low-
Externí odkaz:
https://doaj.org/article/4ec2574b664443c9a2f51e6f8126c763
Autor:
Andrzej Steplewski, Jolanta Fertala, Ryan E Tomlinson, Mark L Wang, Allison Donahue, William V Arnold, Michael Rivlin, Pedro K Beredjiklian, Joseph A Abboud, Surena Namdari, Andrzej Fertala
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257147 (2021)
Posttraumatic fibrotic scarring is a significant medical problem that alters the proper functioning of injured tissues. Current methods to reduce posttraumatic fibrosis rely on anti-inflammatory and anti-proliferative agents with broad intracellular
Externí odkaz:
https://doaj.org/article/df5672a867184f4db745c8d3a4fd6ae5
Autor:
Jolanta Fertala, Michael Rivlin, Mark L. Wang, Pedro K. Beredjiklian, Andrzej Steplewski, Andrzej Fertala
Publikováno v:
Brain and Behavior, Vol 10, Iss 10, Pp n/a-n/a (2020)
Abstract Introduction Posttraumatic scarring of peripheral nerves produces unwanted adhesions that block axonal growth. In the context of surgical nerve repair, the organization of the scar tissue adjacent to conduits used to span the gap between the
Externí odkaz:
https://doaj.org/article/e113714924cb42638d6103ae2b91ecf4
Autor:
Machiko Arita, Jolanta Fertala, Cheryl Hou, James Kostas, Andrzej Steplewski, Andrzej Fertala
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172068 (2017)
Skeletal dysplasias form a group of skeletal disorders caused by mutations in macromolecules of cartilage and bone. The severity of skeletal dysplasias ranges from precocious arthropathy to perinatal lethality. Although the pathomechanisms of these d
Externí odkaz:
https://doaj.org/article/88709c9a3f984a429df21654d8c8c419
Autor:
Sergio A. Jimenez, Natalia Louneva, Jolanta Fertala, Sonsoles Piera-Velazquez, Gonzalo Huaman-Vargas
Publikováno v:
Rheumatology. 59:3092-3098
ObjectiveSSc is a systemic fibrotic disease affecting skin, numerous internal organs and the microvasculature. The molecular pathogenesis of SSc tissue fibrosis has not been fully elucidated, although TGF-β1 plays a crucial role. The Hic-5 protein e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8620ce964a5677a2980efc6adcd2149d
https://doi.org/10.1093/rheumatology/keaa200
https://doi.org/10.1093/rheumatology/keaa200