Altered Ca2+ responses in muscles with combined mitochondrial and cytosolic creatine kinase deficiencies

Autor: Frank Oerlemans, Jolande Koudijs, Karen Steeghs, Benjamin Perryman, Paul H.K. Jap, Arnold de Haan, Arend Heerschap, Dirk Pette, Bé Wieringa, Jan van Deursen, Wim Ruitenbeek, Jacques H. Veerkamp, M.L.P. Brückwilder, Carolina R. Jost, A.A.G.M. Benders

Publikováno v: Cell, 89, pp. 93-103
Steeghs, K, Benders, A, Oerlemans, F, de Haan, A, Heerschap, A, Ruitenbeek, W, Jost, C, Deursen, J, Perryman, B, Pette, D, Br|ckwilder, M, Koudijs, J, Jap, P, Veerkamp, J & Wieringa, B 1997, ' Altered Ca2+ responses in muscles with combined mitochondrial and cytosolic creatine kinase deficiencies ', Cell, vol. 89, pp. 93-103 . https://doi.org/10.1016/S0092-8674(00)80186-5
Cell, 89, 93-103
Cell, 89, 93-103. Cell Press

We have blocked creatine kinase (CK)-mediated phosphocreatine (PCr) ⇃ ATP transphosphorylation in skeletal muscle by combining targeted mutations in the genes encoding mitochondrial and cytosolic CK in mice. Contrary to expectation, the PCr level w

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https://pubmed.ncbi.nlm.nih.gov/9094718