Výsledky vyhledávání - "Jolande Boes"

Measles virus transmembrane fusion protein synthesized de novo or presented in immunostimulating complexes is endogenously processed for HLA class I- and class II-restricted cytotoxic T cell recognition

Autor: Fons G. C. M. Uytdehaag, R.S. van Binnendijk, Jolande Boes, C. A. van Baalen, A.D.M.E. Osterhaus, P de Vries, Martien C. M. Poelen, Vincenzo Cerundolo

Publikováno v: Scopus-Elsevier
The Journal of Experimental Medicine

The routes used by antigen-presenting cells (APC) to convert the transmembrane fusion glycoprotein (F) of measles virus (MV) to HLA class I and class II presentable peptides have been examined, using cloned cytotoxic T lymphocytes in functional assay

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e447ccee8adef6557f71064127645f
https://doi.org/10.1084/jem.176.1.119

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Respiratory syncytial virus infection of monocyte-derived dendritic cells decreases their capacity to activate CD4 T cells

Autor: Esther C. de Jong, Paul J.M. Roholl, Mariska E. A. van Dijk, Grada M. van Bleek, Toni M.M. van Capel, Patricia M. A. de Graaff, Jolande Boes, Jan L. L. Kimpen, Willem Luytjes

Publikováno v: Journal of immunology (Baltimore, Md., 175(9), 5904-5911. American Association of Immunologists

Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections in children, the elderly, and immune-compromised individuals. CD4 and CD8 T cells play a crucial role in the elimination of RSV from the infected lung, bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8249169569e67727261dcff042b5b9b1
https://doi.org/10.4049/jimmunol.175.9.5904

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Impaired Immune Response to Vaccination against Infection with Human Respiratory Syncytial Virus at Advanced Age

Autor: Jolande Boes, Teun Guichelaar, Widjojoatmodjo Myra Noorely, Sylvia S. N. Reemers, Rob Otten, Cécile A. C. M. van Els, Willem Luytjes, Jeroen Hoeboer, Yvonne van Remmerden

Elderly humans are prone to severe infection with human respiratory syncytial virus (HRSV). The aging of today's human population warrants the development of protective vaccination strategies aimed specifically at the elderly. This may require specia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302b3990b5d0f3150d741ea46453a0f0
https://europepmc.org/articles/PMC4136321/

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In vivo antibody response and in vitro CTL activation induced by selected measles vaccine candidates, prepared with purified Quil A components

Autor: Gideon F.A. Kersten, Germie P. J. M. van den Dobbelsteen, Petra de Vries, Kristian Dalsgaard, Arjen Spiekstra, Paul G.H. Mulder, Paul J.M. Roholl, Loek van Alphen, Jolande Boes, Albert D. M. E. Osterhaus, Koert J. Stittelaar

Publikováno v: Vaccine, 18, 2482-2493. Elsevier

Semipurified Quil A and purified Quil A were used to prepare well-characterized subunit vaccine candidates against measles. Variation in the relative amounts of the measles virus (MV) fusion (F) protein, Quil A-components and lipids did not influence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e54a07229c8ef99db7f2b69b4af31c
https://doi.org/10.1016/s0264-410x(00)00026-8

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Infection-enhancing lipopeptides do not improve intranasal immunization of cotton rats with a delta-G candidate live-attenuated human respiratory syncytial virus vaccine

Autor: Yvonne van Remmerden, Rik L. de Swart, D. Tien Nguyen, Albert D. M. E. Osterhaus, Jolande Boes, Teun Guichelaar, Selma Yüksel, Geert van Amerongen

Publikováno v: Human Vaccines & Immunotherapeutics, 9(12), 2578-2583. Landes Bioscience

Development of live-attenuated human respiratory syncytial virus (HRSV) vaccines has proven to be difficult. Several vaccine candidates were found to be over-attenuated and displayed limited immunogenicity. Recently, we identified three synthetic cat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f883a3bd9bf9e79bed40052a0159d4
https://pure.eur.nl/en/publications/9e5638fd-0550-4ea8-8aeb-3048fa60acbf

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Antigenicity and immunogenicity of recombinant envelope glycoproteins of SIVmac32H with different in vivo passage histories

Autor: Marnix L. Bosch, Jolande Boes, Jonathan L. Heeney, Petra de Vries, Guus F. Rimmelzwaan, Albert D. M. E. Osterhaus, Ellen G.J. Hulskotte, Stephen Norley

Publikováno v: Vaccine. 13:1187-1197

Shortly after infection of two rhesus monkeys (Macaca mulatta) either with a SIVmac32H challenge stock or with the same virus that had been passaged in another rhesus monkey for 11 months, SIV-envelope genes were cloned from their peripheral blood mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a593830617c89a13e77041f8a79c52
https://doi.org/10.1016/0264-410x(95)00053-4

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A highly attenuated recombinant human respiratory syncytial virus lacking the G protein induces long-lasting protection in cotton rats

Autor: Marleen van Bers, Willem Luytjes, Paul J.M. Roholl, Yvonne van Remmerden, Jolande Boes, Widjojoatmodjo Myra Noorely

Publikováno v: Virology Journal, Vol 7, Iss 1, p 114 (2010)
Virology Journal

Background Respiratory syncytial virus (RSV) is a primary cause of serious lower respiratory tract illness for which there is still no safe and effective vaccine available. Using reverse genetics, recombinant (r)RSV and an rRSV lacking the G gene (Δ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f97ce16395394908b2dbbb56d4d071
http://www.virologyj.com/content/7/1/114

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Comparison of protection from homologous cell‐free vs cell‐associated SIV challenge afforded by inactivated whole SIV vaccines

Autor: Henk Niphuis, Jolande Boes, Albert D. M. E. Osterhaus, Willem Koornstra, Marlinda E. M. Dings, Rob Dubbes, Jonathan L. Heeney, Bror Morein, Peter ten Haaft, Petra de Vries

Publikováno v: Journal of Medical Primatology. 21:126-130

This study attempted to determine if SIV vaccines could protect against challenge with peripheral blood mononuclear cells (PBMCs) from an SIV infected rhesus monkey. Mature Macaca mulatta were vaccinated four times with formalin inactivated SIVmac32H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a323da65e3b6ac8511bb973a130b14be
https://doi.org/10.1111/j.1600-0684.1992.tb00578.x

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N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response

Autor: John Nieland, Claire J. P. Boog, C. J. M. Melief, Jolande Boes, Jacques Neefjes, M. L. H. De Bruijn, Hidde L. Ploegh

Publikováno v: The Journal of Experimental Medicine

The B6 anti-bm6 allospecific CTL response is strictly dependent on CD4+ cells when using LPS blasts as stimulator cells. Altering the N-linked carbohydrates on stimulator cells by use of the N-linked trimming glycosidase inhibitors 1-deoxymannojirimy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0662bfb2e62c5156b771736e95603a79
https://doi.org/10.1084/jem.171.2.583

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Protection of rhesus macaques from SIV infection by immunization with different experimental SIV vaccines

Autor: Ellen G.J. Hulskotte, Lennart Åkerblom, Marlinda E. M. Dings, Jolande Boes, Sigrid Eriksson, Bror Morein, Peter ten Haaft, Rob Dubbes, S. Norley, Albert D. M. E. Osterhaus, Jonathan L. Heeney, Petra de Vries, Willem Koornstra

Publikováno v: Vaccine. 12(15)

The immunogenicity and efficacy of an inactivated whole SIVmac (32H) preparation adjuvanted with muramyl dipeptide (SIV-MDP) and a gp120-enriched SIVmac (32H) ISCOM preparation (SIV-ISCOM), were compared by immunizing four rhesus macaques (Macaca mul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a965c4244238c6c606211e62cc315ce9
https://pubmed.ncbi.nlm.nih.gov/7887023

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