Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Jolanda M Smit"'
Autor:
Liliana Echavarria-Consuegra, Nilima Dinesh Kumar, Marleen van der Laan, Mario Mauthe, Denise Van de Pol, Fulvio Reggiori, Jolanda M Smit
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0010751 (2023)
Chikungunya virus (CHIKV) is a human pathogen causing outbreaks of febrile illness for which vaccines and specific treatments remain unavailable. Autophagy-related (ATG) proteins and autophagy receptors are a set of host factors that participate in a
Externí odkaz:
https://doaj.org/article/92e78b227bcb424ebd2bcf12ac910d93
Autor:
José Alberto Aguilar Briseño, Lennon Ramos Pereira, Marleen van der Laan, Mindaugas Pauzuolis, Bram M Ter Ellen, Vinit Upasani, Jill Moser, Luís Carlos de Souza Ferreira, Jolanda M Smit, Izabela A Rodenhuis-Zybert
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010499 (2022)
Severe dengue virus (DENV) infection is characterized by exacerbated inflammatory responses that lead to endothelial dysfunction and plasma leakage. We have recently demonstrated that Toll-like receptor 2 (TLR2) on blood monocytes senses DENV infecti
Externí odkaz:
https://doaj.org/article/8ed23dd06b8b42bbac9a4af850b0e6eb
Autor:
Berit Troost-Kind, Martijn J van Hemert, Denise van de Pol, Heidi van der Ende-Metselaar, Andres Merits, Malte Borggrewe, Izabela A Rodenhuis-Zybert, Jolanda M Smit
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009916 (2021)
Tomatidine, a natural steroidal alkaloid from unripe green tomatoes has been shown to exhibit many health benefits. We recently provided in vitro evidence that tomatidine reduces the infectivity of Dengue virus (DENV) and Chikungunya virus (CHIKV), t
Externí odkaz:
https://doaj.org/article/c15790ef693b4450ab597ace566969b1
Autor:
Jorge Andrés Castillo, Diana M Giraldo, Juan C Hernandez, Jolanda M Smit, Izabela A Rodenhuis-Zybert, Silvio Urcuqui-Inchima
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009873 (2021)
A dysregulated or exacerbated inflammatory response is thought to be the key driver of the pathogenesis of severe disease caused by the mosquito-borne dengue virus (DENV). Compounds that restrict virus replication and modulate the inflammatory respon
Externí odkaz:
https://doaj.org/article/63db230099ec4adf8a56a23c23246927
Autor:
Tabitha E Hoornweg, Ellen M Bouma, Denise P I van de Pol, Izabela A Rodenhuis-Zybert, Jolanda M Smit
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008469 (2020)
Chikungunya virus (CHIKV) is a re-emerging mosquito-borne alphavirus, which has rapidly spread around the globe thereby causing millions of infections. CHIKV is an enveloped virus belonging to the Togaviridae family and enters its host cell primarily
Externí odkaz:
https://doaj.org/article/ac8f7c5335ae4a0c822b0baf911cb329
Autor:
Mayra Diosa-Toro, Liliana Echavarría-Consuegra, Jacky Flipse, Geysson Javier Fernández, Joost Kluiver, Anke van den Berg, Silvio Urcuqui-Inchima, Jolanda M Smit
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 10, p e0005981 (2017)
BACKGROUND:Due to the high burden of dengue disease worldwide, a better understanding of the interactions between dengue virus (DENV) and its human host cells is of the utmost importance. Although microRNAs modulate the outcome of several viral infec
Externí odkaz:
https://doaj.org/article/e28e9a848b4546dd94abf55d7d78c16a
Autor:
John F Arboleda Alzate, Izabela A Rodenhuis-Zybert, Juan C Hernández, Jolanda M Smit, Silvio Urcuqui-Inchima
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 10, p e0005904 (2017)
Severe dengue disease is associated with high viral loads and overproduction of pro-inflammatory cytokines, suggesting impairment in the control of dengue virus (DENV) and the mechanisms that regulate cytokine production. Vitamin D3 has been describe
Externí odkaz:
https://doaj.org/article/f0d819264f5d42b7a8f5988ced9edfbd
Autor:
Mariana Ruiz Silva, José A Aguilar Briseño, Vinit Upasani, Heidi van der Ende-Metselaar, Jolanda M Smit, Izabela A Rodenhuis-Zybert
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005712 (2017)
Dengue and chikungunya are viral diseases transmitted to humans by infected Aedes spp. mosquitoes. With an estimated 390 million infected people per year dengue virus (DENV) currently causes the most prevalent arboviral disease. During the last decad
Externí odkaz:
https://doaj.org/article/d35189a11d4d4e96bc40dcb8a978053b
Autor:
Izabela A Rodenhuis-Zybert, Júlia M da Silva Voorham, Silvia Torres, Denise van de Pol, Jolanda M Smit
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003564 (2015)
Humoral immunity plays an important role in controlling dengue virus (DENV) infection. Antibodies (Abs) developed during primary infection protect against subsequent infection with the same dengue serotype, but can enhance disease following secondary
Externí odkaz:
https://doaj.org/article/9388bc5481ce4cbc911db71fbfb81300
Autor:
Jacky Flipse, Jolanda M Smit
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 6, p e0003749 (2015)
Dengue is the most prevalent mosquito-borne viral disease worldwide. Yet, there are no vaccines or specific antivirals available to prevent or treat the disease. Several dengue vaccines are currently in clinical or preclinical stages. The most advanc
Externí odkaz:
https://doaj.org/article/6d6ca136a3b94d06afe2b90810749ea0