Zobrazeno 1 - 10
of 310
pro vyhledávání: '"Jolanda, van der Velden"'
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 8, Iss , Pp 100071- (2024)
Few immortalized cardiac microvascular endothelial cell (CMEC) lines are available, particularly mouse lines. We purchased the CLU510 mCMEC line (Cedarlane), isolated by fluorescence-activated cell sorting for CD31 and VE-cadherin. The cell line has
Externí odkaz:
https://doaj.org/article/d61490114afc43a083f56b05a38e9934
Autor:
Verena Schwach, Rolf H. Slaats, Carla Cofiño-Fabres, Simone A. ten Den, José M. Rivera-Arbeláez, Maureen Dannenberg, Chiara van Boheemen, Marcelo C. Ribeiro, Sabina Y. van der Zanden, Edgar E. Nollet, Jolanda van der Velden, Jacques Neefjes, Lu Cao, Robert Passier
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109139- (2024)
Summary: Cardiotoxicity remains a major cause of drug withdrawal, partially due to lacking predictability of animal models. Additionally, risk of cardiotoxicity following treatment of cancer patients is treatment limiting. It is unclear which patient
Externí odkaz:
https://doaj.org/article/53a15164b1784b66b4caea6027524cc5
Autor:
Edgar E. Nollet, Sila Algül, Max Goebel, Saskia Schlossarek, Nicole N. van der Wel, Judith J.M. Jans, Mark A. van de Wiel, Jaco C. Knol, Thang V. Pham, Sander R. Piersma, Richard de Goeij-de Haas, Jill Hermans, Jan Bert van Klinken, Michel van Weeghel, Riekelt H. Houtkooper, Lucie Carrier, Connie R. Jimenez, Diederik W.D. Kuster, Jolanda van der Velden
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 6, Iss , Pp 100050- (2023)
Background and aim: Phenotypic expression of hypertrophic cardiomyopathy (HCM) and disease course are associated with unfavorable metabolic health. We investigated if Western diet (WD) feeding is sufficient to trigger cardiac hypertrophy and dysfunct
Externí odkaz:
https://doaj.org/article/a35423357cb242d7a31ba3d7bed60292
Autor:
Sofija Vučković, Rafeeh Dinani, Edgar E. Nollet, Diederik W. D. Kuster, Jan Willem Buikema, Riekelt H. Houtkooper, Miranda Nabben, Jolanda van der Velden, Birgit Goversen
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have emerged as a powerful tool for disease modeling, though their immature nature currently limits translation into clinical practice. Maturation strategies increasi
Externí odkaz:
https://doaj.org/article/bb40feeeeb3d4261ada3ef35f1e56c6f
Autor:
Jolanda van der Velden
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 2, Iss , Pp 100021- (2022)
Externí odkaz:
https://doaj.org/article/83657b79a702402a8055b25ee26450c6
Autor:
Vasco Sequeira, Lili Wang, Paul J.M. Wijnker, Kyungsoo Kim, Jose R. Pinto, Cris dos Remedios, Charles Redwood, Bjorn C. Knollmann, Jolanda van der Velden
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 1, Iss , Pp 100007- (2022)
Background: Hypertrophic cardiomyopathy (HCM) is an autosomal dominant genetic disorder with patients typically showing heterozygous inheritance of a pathogenic variant in a gene encoding a contractile protein. Here, we study the contractile effects
Externí odkaz:
https://doaj.org/article/b360c922580f4c239424f598c7d8a20a
Autor:
Valentin Burkart, Kathrin Kowalski, David Aldag-Niebling, Julia Beck, Dirk Alexander Frick, Tim Holler, Ante Radocaj, Birgit Piep, Andre Zeug, Denise Hilfiker-Kleiner, Cristobal G. dos Remedios, Jolanda van der Velden, Judith Montag, Theresia Kraft
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Transcriptional bursting is a common expression mode for most genes where independent transcription of alleles leads to different ratios of allelic mRNA from cell to cell. Here we investigated burst-like transcription and its consequences in cardiac
Externí odkaz:
https://doaj.org/article/b474c750ea6f47e1a619c482725c63c5
Autor:
Alessia Argirò, Carolyn Ho, Sharlene M. Day, Jolanda van der Velden, Elisabetta Cerbai, Sara Saberi, Jil C. Tardiff, Neal K. Lakdawala, Iacopo Olivotto
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 9 (2022)
Cardiomyopathies are a heterogeneous collection of diseases that have in common primary functional and structural abnormalities of the heart muscle, often genetically determined. The most effective categorization of cardiomyopathies is based on the p
Externí odkaz:
https://doaj.org/article/f96e6077fb684b2a939552ca9ab2ed06
Autor:
Dorien Deluyker, Lize Evens, Sibren Haesen, Ronald B. Driesen, Diederik Kuster, Maxim Verboven, Hanne Beliën, Jolanda van der Velden, Ivo Lambrichts, Virginie Bito
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 5, Pp 809-824 (2020)
Externí odkaz:
https://doaj.org/article/215b5c4cc079425ca18da3260f1a5861
Autor:
Rio P. Juni, PhD, Diederik W.D. Kuster, PhD, Max Goebel, MSc, Michiel Helmes, PhD, René J.P. Musters, PhD, Jolanda van der Velden, PhD, Pieter Koolwijk, PhD, Walter J. Paulus, MD, PhD, Victor W.M. van Hinsbergh, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 5, Pp 575-591 (2019)
Summary: The positive findings of the EMPA-REG OUTCOME trial (Randomized, Placebo-Controlled Cardiovascular Outcome Trial of Empagliflozin) on heart failure (HF) outcome in patients with type 2 diabetes mellitus suggest a direct effect of empaglifloz
Externí odkaz:
https://doaj.org/article/3ed290af219b4583a9eb3ca67de459dc