Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Joke H. de Boer"'
Autor:
Carlyn V. Kouwenberg, Julia Spierings, Evianne L. de Groot, Joke H. de Boer, Viera Kalinina Ayuso
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 21, Iss 1, Pp 1-9 (2023)
Abstract Background Pediatric uveitis is a severe inflammatory ocular condition that can lead to sight-threatening complications and can negatively impact quality of life. The retinal microcirculation is often affected in intermediate uveitis and pan
Externí odkaz:
https://doaj.org/article/0da3e17bef124cbab2a6f01b1e336c63
Autor:
Wouter J. Venema, Sanne Hiddingh, Jorg van Loosdregt, John Bowes, Brunilda Balliu, Joke H. de Boer, Jeannette Ossewaarde-van Norel, Susan D. Thompson, Carl D. Langefeld, Aafke de Ligt, Lars T. van der Veken, Peter H.L. Krijger, Wouter de Laat, Jonas J.W. Kuiper
Publikováno v:
Cell Genomics, Vol 4, Iss 1, Pp 100460- (2024)
Summary: Single-nucleotide polymorphisms (SNPs) near the ERAP2 gene are associated with various autoimmune conditions, as well as protection against lethal infections. Due to high linkage disequilibrium, numerous trait-associated SNPs are correlated
Externí odkaz:
https://doaj.org/article/ef5055cff96b4f289ee5f7103baea2ba
Autor:
Daphne P.C. Vergouwen, MD, P. Martijn Kolijn, MSc, Joeri de Hoog, MD, Joke H. de Boer, MD, PhD, Leonoor I. Los, MD, PhD, Marlies Gijs, PhD, Roel J. Erckens, MD, PhD, Pascal H.P. de Jong, MD, PhD, Aniki Rothova, MD, PhD, Josianne C. Ten Berge, MD, PhD, Marco W.J. Schreurs, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 1, Pp 100407- (2024)
Purpose: Scleritis is an extremely painful and potentially blinding inflammation of the sclera with unknown pathogenesis and unpredictable course. To gain insight in its disease process and identify biomarker candidates, we performed extensive proteo
Externí odkaz:
https://doaj.org/article/48f096aef60a49f2a3b09cde21def082
Autor:
Johanna L. Heinz, Sigrid M. A. Swagemakers, Joanna von Hofsten, Marie Helleberg, Michelle M. Thomsen, Kerstin De Keukeleere, Joke H. de Boer, Tomas Ilginis, Georges M. G. M. Verjans, Peter M. van Hagen, Peter J. van der Spek, Trine H. Mogensen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
PurposeHerpes simplex virus (HSV) and varicella-zoster virus (VZV) are neurotropic human alphaherpesviruses endemic worldwide. Upon primary infection, both viruses establish lifelong latency in neurons and reactivate intermittently to cause a variety
Externí odkaz:
https://doaj.org/article/2755a6e1e135421ea6420d24946ac46e
Autor:
Jonas J.W. Kuiper, PhD, Fleurieke H. Verhagen, MD, PhD, Sanne Hiddingh, MSc, Roos A.W. Wennink, MD, Anna M. Hansen, PhD, Kerry A. Casey, PhD, Imo E. Hoefer, PhD, Saskia Haitjema, PhD, Julia Drylewicz, PhD, Mehmet Yakin, MD, H. Nida Sen, MD, PhD, Timothy R.D. J. Radstake, MD, PhD, Joke H. de Boer, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 2, Iss 3, Pp 100175- (2022)
Purpose: Early identification of patients with noninfectious uveitis requiring steroid-sparing immunomodulatory therapy (IMT) is currently lacking in objective molecular biomarkers. We evaluated the proteomic signature of patients at the onset of dis
Externí odkaz:
https://doaj.org/article/1a5195b0ade9461daf64977b6003d89a
Autor:
Wouter J. Venema, Sanne Hiddingh, Joke H. de Boer, Frans H. J. Claas, Arend Mulder, Anneke I. den Hollander, Efstratios Stratikos, Siranush Sarkizova, Lars T. van der Veken, George M. C. Janssen, Peter A. van Veelen, Jonas J. W. Kuiper
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Birdshot Uveitis (BU) is a blinding inflammatory eye condition that only affects HLA-A29-positive individuals. Genetic association studies linked ERAP2 with BU, an aminopeptidase which trims peptides before their presentation by HLA class I at the ce
Externí odkaz:
https://doaj.org/article/96774bd91fe94255b5f0907aab6bb0ce
Autor:
Evianne L. de Groot, Jeannette Ossewaarde - van Norel, Lintje Ho, Ninette H. ten Dam - van Loon, Joke H. de Boer
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 20, Iss , Pp 100921- (2020)
Purpose: To evaluate the efficacy of adalimumab in patients with central multifocal choroiditis (cMFC) refractory to conventional corticosteroid-sparing immunomodulatory agents (IMT). Methods: Medical records were reviewed from all patients with cMFC
Externí odkaz:
https://doaj.org/article/280f1aa1b8484995b43c83dd25ab08fa
Autor:
Roos A. W. Wennink, Aridaman Pandit, Anne-Mieke J. W. Haasnoot, Sanne Hiddingh, Viera Kalinina Ayuso, Nico M. Wulffraat, Bas J. Vastert, Timothy R. D. J. Radstake, Joke H. de Boer, Jonas J. W. Kuiper
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
PurposePatients with juvenile idiopathic arthritis (JIA) are prone to developing chronic anterior uveitis (JIA-U+). Although several risk factors for JIA-U+ have been identified, the underlying etiology is poorly understood. Histopathological studies
Externí odkaz:
https://doaj.org/article/798a79d0191346309a8ded76b587a23f
Autor:
Fleurieke H. Verhagen, Sanne Hiddingh, Rianne Rijken, Aridaman Pandit, Emmerik Leijten, Michel Olde Nordkamp, Ninette H. ten Dam-van Loon, Stefan Nierkens, Saskia M. Imhof, Joke H. de Boer, Timothy R. D. J. Radstake, Jonas J. W. Kuiper
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: Non-infectious uveitis (NIU) is a severe intra ocular inflammation, which frequently requires prompt systemic immunosuppressive therapy (IMT) to halt the development of vision-threatening complications. IMT is considered when NIU cannot b
Externí odkaz:
https://doaj.org/article/2bf4075200f2421d96614479395ebbc5
Autor:
Evianne L. de Groot, Ninette H. ten Dam-van Loon, Carlyn V. Kouwenberg, Joke H. de Boer, Jeannette Ossewaarde-van Norel
Publikováno v:
American Journal of Ophthalmology. 252:45-58