Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Joji Nagasaki"'
Autor:
Joji Nagasaki, Mitsutaka Nishimoto, Hideo Koh, Hiroshi Okamura, Mika Nakamae, Kazuki Sakatoku, Kentaro Ido, Masatomo Kuno, Yosuke Makuuchi, Teruhito Takakuwa, Yasuhiro Nakashima, Masayuki Hino, Hirohisa Nakamae
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/08be12c9280347749932318cb057c123
Autor:
Wenhao Zhou, Shusuke Kawashima, Takamasa Ishino, Katsushige Kawase, Youki Ueda, Kazuo Yamashita, Tomofumi Watanabe, Masahito Kawazu, Hiromichi Dansako, Yutaka Suzuki, Hiroyoshi Nishikawa, Takashi Inozume, Joji Nagasaki, Yosuke Togashi
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113797- (2024)
Summary: Immune checkpoint inhibitors exert clinical efficacy against various types of cancer through reinvigoration of exhausted CD8+ T cells that attack cancer cells directly in the tumor microenvironment (TME). Using single-cell sequencing and mou
Externí odkaz:
https://doaj.org/article/a16afc6c6d2a44839375efb4ad0cb6e6
Autor:
Hideki Ikeda, MD, Joji Nagasaki, MD, PhD, Daiki Shimizu, MD, Yuki Katsuya, MD, PhD, Hidehito Horinouchi, MD, PhD, Yukio Hosomi, MD, PhD, Etsuko Tanji, MS, Takekazu Iwata, MD, PhD, Makiko Itami, MD, PhD, Masahito Kawazu, MD, PhD, Yuichiro Ohe, MD, PhD, Takuji Suzuki, MD, PhD, Yosuke Togashi, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 10, Pp 100573- (2023)
Introduction: Unresectable or recurrent thymic epithelial tumors (TETs) have a poor prognosis, and treatment options are limited. This study aimed to investigate the immunologic significance of CD80/CD86 or major histocompatibility complex class II (
Externí odkaz:
https://doaj.org/article/e22f91bb33b34c45b99ef4b5ba01a266
Autor:
Yosuke Togashi, Hiroyoshi Nishikawa, Yutaka Suzuki, Yasuhiro Nakamura, Tomonori Kawasaki, Yuzuru Ikehara, Shusuke Kawashima, Takashi Inozume, Masahito Kawazu, Toshihide Ueno, Joji Nagasaki, Etsuko Tanji, Akiko Honobe, Takehiro Ohnuma, Tatsuyoshi Kawamura, Yoshiyasu Umeda, Yukiko Kiniwa, Osamu Yamasaki, Satoshi Fukushima, Hiroyuki Mano, Hiroyuki Matsue
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/8ab52d59167c472a99dacd4ff3db0b31
Autor:
Joji Nagasaki, Masahiro Manabe, Kentaro Ido, Hiroyoshi Ichihara, Yasutaka Aoyama, Tadanobu Ohta, Yoshio Furukawa, Atsuko Mugitani
Publikováno v:
Case Reports in Hematology, Vol 2016 (2016)
The etiologies of secondary idiopathic thrombocytopenic purpura (ITP) include infection, autoimmune disease, and immunodeficiency. We report the cases of three elderly patients who developed ITP after receiving influenza vaccinations. The platelet co
Externí odkaz:
https://doaj.org/article/323a70604c474077981016a866671e26
Autor:
Katsushige Kawase, Shusuke Kawashima, Joji Nagasaki, Takashi Inozume, Etsuko Tanji, Masahito Kawazu, Toyoyuki Hanazawa, Yosuke Togashi
Publikováno v:
Cancer Immunology Research. :OF1-OF14
IFNγ signaling pathway defects are well-known mechanisms of resistance to immune checkpoint inhibitors. However, conflicting data have been reported, and the detailed mechanisms remain unclear. In this study, we have demonstrated that resistance to
Autor:
Tomofumi Watanabe, Takamasa Ishino, Youki Ueda, Joji Nagasaki, Takuya Sadahira, Hiromichi Dansako, Motoo Araki, Yosuke Togashi
Publikováno v:
Cancer Science. 114:1859-1870
Combination therapy with anti-cytotoxic T lymphocyte-associated protein 4 (CTLA-4) and anti-programmed death-1 (PD-1) monoclonal antibodies (mAbs) has dramatically improved the prognosis of patients with multiple types of cancer, including renal cell
Autor:
Takao Morinaga, Takashi Inozume, Masahito Kawazu, Youki Ueda, Nicolas Sax, Kazuo Yamashita, Shusuke Kawashima, Joji Nagasaki, Toshihide Ueno, Jason Lin, Yuuki Ohara, Takeshi Kuwata, Hiroki Yukami, Akihito Kawazoe, Kohei Shitara, Akiko Honobe-Tabuchi, Takehiro Ohnuma, Tatsuyoshi Kawamura, Yoshiyasu Umeda, Yu Kawahara, Yasuhiro Nakamura, Yukiko Kiniwa, Ayako Morita, Eiki Ichihara, Katsuyuki Kiura, Tomohiro Enokida, Makoto Tahara, Yoshinori Hasegawa, Hiroyuki Mano, Yutaka Suzuki, Hiroyoshi Nishikawa, Yosuke Togashi
Publikováno v:
Cancer Research Communications. 2:739-753
Some patients experience mixed response to immunotherapy, whose biological mechanisms and clinical impact have been obscure. We obtained two tumor samples from lymph node (LN) metastatic lesions in a same patient. Whole exome sequencing for the both
Autor:
Yosuke Togashi, Toyoyuki Hanazawa, Masahito Kawazu, Etsuko Tanji, Takashi Inozume, Joji Nagasaki, Shusuke Kawashima, Katsushige Kawase
Supplementary Figure S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11509e084f8d341e35fbc028e0648cf6
https://doi.org/10.1158/2326-6066.22640286
https://doi.org/10.1158/2326-6066.22640286
Autor:
Yosuke Togashi, Toyoyuki Hanazawa, Masahito Kawazu, Etsuko Tanji, Takashi Inozume, Joji Nagasaki, Shusuke Kawashima, Katsushige Kawase
IFNγ signaling pathway defects are well-known mechanisms of resistance to immune checkpoint inhibitors. However, conflicting data have been reported, and the detailed mechanisms remain unclear. In this study, we have demonstrated that resistance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0505ac2db150b4083d6618341a3b06
https://doi.org/10.1158/2326-6066.c.6601461.v1
https://doi.org/10.1158/2326-6066.c.6601461.v1