Post-operative Crohn's Disease Recurrence and Infectious Complications: A Transcriptomic Analysis.

Autor: Chen KA; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA.; Department of Surgery, University of North Carolina at Chapel Hill, 100 Manning Drive, Burnett Womack Building, Suite 4038, Chapel Hill, NC, 27599, USA., Gartner V; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA., Darlington KC; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA., Silverstein SR; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA., Kennedy Ng MM; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA., Butler L; Department of Surgery, University of North Carolina at Chapel Hill, 100 Manning Drive, Burnett Womack Building, Suite 4038, Chapel Hill, NC, 27599, USA., Avalos K; Department of Surgery, University of North Carolina at Chapel Hill, 100 Manning Drive, Burnett Womack Building, Suite 4038, Chapel Hill, NC, 27599, USA., Nishiyama NC; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA., Joisa CU; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, 10202C Mary Ellen Jones Building, Chapel Hill, NC, 27599, USA., Schaner MR; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA., Lian G; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA., Beasley C; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA., Lau GW; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA., Bauer MJ; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA., Zhu LC; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, CB #7525, Brinkhous-Bullitt Building, Chapel Hill, NC, 27599, USA., Kapadia MR; Department of Surgery, University of North Carolina at Chapel Hill, 100 Manning Drive, Burnett Womack Building, Suite 4038, Chapel Hill, NC, 27599, USA., Gomez SM; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, 10202C Mary Ellen Jones Building, Chapel Hill, NC, 27599, USA., Furey TS; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA. tsfurey@email.unc.edu.; Department of Genetics, Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, 5000D Genetic Medicine Building, 120 Mason Farm Road, Chapel Hill, NC, CB #726427599, USA. tsfurey@email.unc.edu., Sheikh SZ; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Bioinformatics Building; CB #7555, 130 Mason Farm Road, Chapel Hill, NC, 27599, USA.; University of North Carolina at Chapel Hill, 7314 Medical Biomolecular Research Building, 111 Mason Farm Road, Chapel Hill, NC, 27599, USA.

Publikováno v: Digestive diseases and sciences [Dig Dis Sci] 2024 Aug 31. Date of Electronic Publication: 2024 Aug 31.

Prediction of Pathologic Complete Response for Rectal Cancer Based on Pretreatment Factors Using Machine Learning.

Autor: Chen KA; Division of Gastrointestinal Surgery, Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Goffredo P; Division of Colorectal Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minnesota., Butler LR; Division of Gastrointestinal Surgery, Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Joisa CU; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Guillem JG; Division of Gastrointestinal Surgery, Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Gomez SM; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina., Kapadia MR; Division of Gastrointestinal Surgery, Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Publikováno v: Diseases of the colon and rectum [Dis Colon Rectum] 2024 Mar 01; Vol. 67 (3), pp. 387-397. Date of Electronic Publication: 2023 Nov 16.

Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies.

Autor: Joisa CU; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA2North Carolina State University, Raleigh, NC, USA3Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Chen KA, Beville S, Stuhlmiller T, Berginski ME, Okumu D, Golitz BT, East MP, Johnson GL, Gomez SM

Publikováno v: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing [Pac Symp Biocomput] 2024; Vol. 29, pp. 276-290.

Integrated single-dose kinome profiling data is predictive of cancer cell line sensitivity to kinase inhibitors.

Autor: Joisa CU; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC, United States of America., Chen KA; Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America., Berginski ME; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America., Golitz BT; Eshelman Institute for Innovation, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America., Jenner MR; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America., Herrera Loeza G; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America., Yeh JJ; Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America., Gomez SM; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC, United States of America.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.

Publikováno v: PeerJ [PeerJ] 2023 Nov 16; Vol. 11, pp. e16342. Date of Electronic Publication: 2023 Nov 16 (Print Publication: 2023).

Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies.

Autor: Joisa CU; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA and North Carolina State University, Raleigh, NC, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Chen KA; Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Beville S; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Stuhlmiller T; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Berginski ME; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Okumu D; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Golitz BT; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Johnson GL; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gomez SM; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA and North Carolina State University, Raleigh, NC, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Aug 03. Date of Electronic Publication: 2023 Aug 03.