Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Johny Pires"'
Autor:
Ana R.A.A. Quadros, Rocío Díez Arazola, Andrea Romaguera Álvarez, Johny Pires, Rhiannon M. Meredith, Ingrid Saarloos, Matthijs Verhage, Ruud F. Toonen
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104069- (2022)
Summary: FBXO41 is a neuron-specific E3 ligase subunit implicated in epileptic encephalopathies. Fbxo41 null mutant (KO) mice show behavioral deficits and early lethality. Here, we report that loss of FBXO41 causes defects in synaptic transmission an
Externí odkaz:
https://doaj.org/article/260425520815456793f1b1359ddeb30b
Autor:
Ana R.A.A. Quadros, Rocío Díez Arazola, Andrea Romaguera Álvarez, Johny Pires, Rhiannon M. Meredith, Ingrid Saarloos, Matthijs Verhage, Ruud F. Toonen
Publikováno v:
iScience, 25(4):104069. Elsevier Inc.
Quadros, A R A A, Arazola, R D, Álvarez, A R, Pires, J, Meredith, R M, Saarloos, I, Verhage, M & Toonen, R F 2022, ' Neuronal F-Box protein FBXO41 regulates synaptic transmission and hippocampal network maturation ', iScience, vol. 25, no. 4, 104069, pp. 1-18 . https://doi.org/10.1016/j.isci.2022.104069
Quadros, A R A A, Arazola, R D E, Álvarez, A R, Pires, J, Meredith, R M, Saarloos, I, Verhage, M & Toonen, R F 2022, ' Neuronal F-Box protein FBXO41 regulates synaptic transmission and hippocampal network maturation ', iScience, vol. 25, no. 4, 104069 . https://doi.org/10.1016/j.isci.2022.104069
iScience, 25(4):104069, 1-18. Elsevier
Quadros, A R A A, Arazola, R D, Álvarez, A R, Pires, J, Meredith, R M, Saarloos, I, Verhage, M & Toonen, R F 2022, ' Neuronal F-Box protein FBXO41 regulates synaptic transmission and hippocampal network maturation ', iScience, vol. 25, no. 4, 104069, pp. 1-18 . https://doi.org/10.1016/j.isci.2022.104069
Quadros, A R A A, Arazola, R D E, Álvarez, A R, Pires, J, Meredith, R M, Saarloos, I, Verhage, M & Toonen, R F 2022, ' Neuronal F-Box protein FBXO41 regulates synaptic transmission and hippocampal network maturation ', iScience, vol. 25, no. 4, 104069 . https://doi.org/10.1016/j.isci.2022.104069
iScience, 25(4):104069, 1-18. Elsevier
FBXO41 is a neuron-specific E3 ligase subunit implicated in epileptic encephalopathies. Fbxo41 null mutant (KO) mice show behavioral deficits and early lethality. Here, we report that loss of FBXO41 causes defects in synaptic transmission and brain d
Publikováno v:
Developmental Neurobiology
Pires, J, Nelissen, R, Mansvelder, H D & Meredith, R M 2021, ' Spontaneous synchronous network activity in the neonatal development of mPFC in mice ', Developmental Neurobiology, vol. 81, no. 2, pp. 207-225 . https://doi.org/10.1002/dneu.22811
Developmental Neurobiology, 81(2), 207-225. John Wiley and Sons Inc.
Pires, J, Nelissen, R, Mansvelder, H D & Meredith, R M 2021, ' Spontaneous synchronous network activity in the neonatal development of mPFC in mice ', Developmental Neurobiology, vol. 81, no. 2, pp. 207-225 . https://doi.org/10.1002/dneu.22811
Developmental Neurobiology, 81(2), 207-225. John Wiley and Sons Inc.
Spontaneous Synchronous Network Activity (SSA) is a hallmark of neurodevelopment found in numerous central nervous system structures, including neocortex. SSA occurs during restricted developmental time-windows, commonly referred to as critical perio
Autor:
Julia Dawitz, Janna A. Berkhout, Tim Kroon, Huibert D. Mansvelder, Mihai Alevra, Vivi M. Heine, J. J. Johannes Hjorth, Valerie J. Dassen, Johny Pires, Aish G. Nadadhur, Ruud F. Toonen, Javier Emperador Melero, Rhiannon M. Meredith
Publikováno v:
Developmental Neurobiology. 76:357-374
Developing networks in the immature nervous system and in cellular cultures are characterized by waves of synchronous activity in restricted clusters of cells. Synchronized activity in immature networks is proposed to regulate many different developm
Autor:
Ricardo Gouveia Rodrigues, Cristina Lemos, Paula M. Canas, Joana Marques, Attila Köfalvi, Anna Pliássova, Rodrigo A. Cunha, Daniel Rial, Rui O. Beleza, Francisco Q. Gonçalves, Johny Pires
Publikováno v:
European Journal of Neuroscience. 41:878-888
Adenosine is a neuromodulator mostly acting through A1 (inhibitory) and A2A (excitatory) receptors in the brain. A2B receptors (A(2B)R) are G(s/q)--protein-coupled receptors with low expression in the brain. As A(2B)R function is largely unknown, we
Autor:
Juracy Marques, Rui A. Carvalho, R.J. Rodrigues, Cristina Lemos, Johny Pires, Flávio Reis, Honorio Silva, Rui Daniel Prediger, Ivana Jarak, Fábio Claudiney da Costa Pereira, A.C. da Silva, Rodrigo A. Cunha, Daniel Rial, Filipe C. Matheus, Fernanda Gonçalves
Publikováno v:
Neuroscience. 315
High sugar consumption is a risk factor for metabolic disturbances leading to memory impairment. Thus, rats subject to high sucrose intake (HSu) develop a metabolic syndrome and display memory deficits. We now investigated if these HSu-induced memory
Autor:
Johannes J J, Hjorth, Julia, Dawitz, Tim, Kroon, Johny, Pires, Valerie J, Dassen, Janna A, Berkhout, Javier, Emperador Melero, Aish G, Nadadhur, Mihai, Alevra, Ruud F, Toonen, Vivi M, Heine, Huibert D, Mansvelder, Rhiannon M, Meredith
Publikováno v:
Developmental neurobiology. 76(4)
Developing networks in the immature nervous system and in cellular cultures are characterized by waves of synchronous activity in restricted clusters of cells. Synchronized activity in immature networks is proposed to regulate many different developm