The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases.

Autor: Harden JL; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY. Electronic address: jharden@rockefeller.edu., Lewis SM; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY., Lish SR; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY., Suárez-Fariñas M; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY; Center for Clinical and Translational Science, Rockefeller University, New York, NY; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY., Gareau D; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY., Lentini T; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY., Johnson-Huang LM; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY., Krueger JG; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY., Lowes MA; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY; Division of Dermatology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2016 Jun; Vol. 137 (6), pp. 1830-1840. Date of Electronic Publication: 2015 Dec 22.

IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model.

Autor: Chiricozzi A; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America ; Center for Clinical and Translational Science, The Rockefeller University, New York City, New York, United States of America ; Department of Dermatology, University of Rome 'Tor Vergata', Rome, Italy., Nograles KE; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America ; Center for Clinical and Translational Science, The Rockefeller University, New York City, New York, United States of America., Johnson-Huang LM; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America., Fuentes-Duculan J; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America., Cardinale I; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America., Bonifacio KM; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America., Gulati N; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America., Mitsui H; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America., Guttman-Yassky E; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America ; Center for Clinical and Translational Science, The Rockefeller University, New York City, New York, United States of America ; Department of Dermatology, Mount Sinai School of Medicine, New York City, New York, United States of America., Suárez-Fariñas M; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America ; Center for Clinical and Translational Science, The Rockefeller University, New York City, New York, United States of America., Krueger JG; Laboratory for Investigative Dermatology, The Rockefeller University, New York City, New York, United States of America ; Center for Clinical and Translational Science, The Rockefeller University, New York City, New York, United States of America.

Publikováno v: PloS one [PLoS One] 2014 Feb 28; Vol. 9 (2), pp. e90284. Date of Electronic Publication: 2014 Feb 28 (Print Publication: 2014).

Gene profiling of narrowband UVB-induced skin injury defines cellular and molecular innate immune responses.

Autor: Kennedy Crispin M; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA., Fuentes-Duculan J; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA., Gulati N; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA., Johnson-Huang LM; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA., Lentini T; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA., Sullivan-Whalen M; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA., Gilleaudeau P; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA., Cueto I; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA., Suárez-Fariñas M; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA; The Center for Clinical and Translational Science, Rockefeller University, New York, New York, USA., Lowes MA; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA., Krueger JG; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA. Electronic address: kruegej@rockefeller.edu.

Publikováno v: The Journal of investigative dermatology [J Invest Dermatol] 2013 Mar; Vol. 133 (3), pp. 692-701. Date of Electronic Publication: 2012 Nov 15.

A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin.

Autor: Johnson-Huang LM; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York 10065, USA., Suárez-Fariñas M, Pierson KC, Fuentes-Duculan J, Cueto I, Lentini T, Sullivan-Whalen M, Gilleaudeau P, Krueger JG, Haider AS, Lowes MA

Publikováno v: The Journal of investigative dermatology [J Invest Dermatol] 2012 Apr; Vol. 132 (4), pp. 1177-87. Date of Electronic Publication: 2012 Jan 26.

Post-therapeutic relapse of psoriasis after CD11a blockade is associated with T cells and inflammatory myeloid DCs.

Autor: Johnson-Huang LM; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, United States of America., Pensabene CA, Shah KR, Pierson KC, Kikuchi T, Lentini T, Gilleaudeau P, Sullivan-Whalen M, Cueto I, Khatcherian A, Hyder LA, Suárez-Fariñas M, Krueger JG, Lowes MA

Publikováno v: PloS one [PLoS One] 2012; Vol. 7 (2), pp. e30308. Date of Electronic Publication: 2012 Feb 10.