Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Johnson Yiu Nam Lau"'
Autor:
Wu Zeng, Betty Yuen Kwan Law, Vincent Kam Wai Wong, Denise So Bik Chan, Simon Wing Fai Mok, Joyce Jia Ying Gao, Rebecca Ka Yan Ho, Xu Liang, Jia Hao Li, Ming Tsung Lee, Weng Li Yoon, Michael P Smolinski, Johnson Yiu Nam Lau, Christopher Wai Kei Lam, Manson Fok
Publikováno v:
Cancer Biology & Medicine, Vol 17, Iss 4, Pp 986-1001 (2020)
Objective: Delivery of chemotherapeutic drugs to the brain has remained a major obstacle in the treatment of glioma, owing to the presence of the blood-brain barrier and the activity of P-gp, which pumps its substrate back into the systemic circulati
Externí odkaz:
https://doaj.org/article/0a638d70084946c8a525f147a5248048
Autor:
Shuofeng Yuan, Hin Chu, Jasper Fuk-Woo Chan, Zi-Wei Ye, Lei Wen, Bingpeng Yan, Pok-Man Lai, Kah-Meng Tee, Jingjing Huang, Dongdong Chen, Cun Li, Xiaoyu Zhao, Dong Yang, Man Chun Chiu, Cyril Yip, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Kong-Hung Sze, Jie Zhou, Ivy Hau-Yee Chan, Kin-Hang Kok, Kelvin Kai-Wang To, Richard Yi-Tsun Kao, Johnson Yiu-Nam Lau, Dong-Yan Jin, Stanley Perlman, Kwok-Yung Yuen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Viruses rely on host cell metabolism for replication, making these pathways potential therapeutic targets. Here, the authors show that AM580, a retinoid derivative and RAR-α agonist, affects replication of several RNA viruses by interfering with the
Externí odkaz:
https://doaj.org/article/c1c5fe348ab54b8eb38874751717d9b6
Autor:
Kuo-Ming, Yu, Ping, Yang, Tien-Yu, Huang, Thomas Yen-Shih, Shen, Johnson Yiu-Nam, Lau, Oliver Yoa-Pu, Hu
Publikováno v:
Analytical and Bioanalytical Chemistry. 414:4067-4077
Liver disease has emerged as a healthcare burden because of high hospitalization rates attributed both to steatohepatitis and to severe hepatic toxicity associated with changes of drug exposure. Early detection of hepatic insufficiency is critical to
Autor:
Lixiang Zhai, Chunhua Huang, Ziwan Ning, Yijing Zhang, Min Zhuang, Wei Yang, Xiaolei Wang, Jingjing Wang, Eric Lu Zhang, Haitao Xiao, Ling Zhao, Yan Y Lam, Chi-Fung Willis Chow, Jiandong Huang, Shuofeng Yuan, Kui-Ming Chan, Chun-Su Yuan, Johnson Yiu-Nam Lau, Hoi-Leong Xavier Wong, Zhao-Xiang Bian
Publikováno v:
Basic Gastroenterology.
Publikováno v:
MedComm – Future Medicine. 1
Autor:
Lixiang Zhai, Chunhua Huang, Ziwan Ning, Yijing Zhang, Min Zhuang, Wei Yang, Xiaolei Wang, Jingjing Wang, Lu Zhang, Haitao Xiao, Ling Zhao, Pallavi Asthana, Yan Y. Lam, Chi Fung Willis Chow, Jian-dong Huang, Shuofeng Yuan, Kui Ming Chan, Chun-Su Yuan, Johnson Yiu-Nam Lau, Hoi Leong Xavier Wong, Zhao-xiang Bian
Publikováno v:
Cell hostmicrobe.
Diarrhea-predominant irritable bowel syndrome (IBS-D), a globally prevalent functional gastrointestinal (GI) disorder, is associated with elevated serotonin that increases gut motility. While anecdotal evidence suggests that the gut microbiota contri
Autor:
Peng Du, Man Miao, Kang Zhang, Andy Peng Xiang, Meixing Yu, Zhongcheng Zhou, Daniel T. Baptista-Hon, Gen Li, Johnson Yiu-Nam Lau
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-3 (2021)
Publikováno v:
Precision Clinical Medicine
The SARS-CoV-2 Delta variant has evolved as the dominant strain of the current pandemic. Studies have shown that this variant has increased infectivity/viral load, and reduced neutralization by the host antibodies from convalescent patients/vaccinees
Autor:
Kong-Hung Sze, Johnson Yiu-Nam Lau, Ivy Hau-Yee Chan, Zi-Wei Ye, Pok Man Lai, Richard Y.T. Kao, Dong Yang, Cyril C. Y. Yip, Lei Wen, Chris Chung-Sing Chan, Kwok-Yung Yuen, Jasper Fuk-Woo Chan, Man Chun Chiu, Xiaoyu Zhao, Bingpeng Yan, Shuofeng Yuan, Dongdong Chen, Cun Li, Dong-Yan Jin, Kelvin K. W. To, Jingjing Huang, Kin-Hang Kok, Stanley Perlman, Hin Chu, Vincent Kwok-Man Poon, Jie Zhou, Kah Meng Tee
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Viruses are obligate intracellular microbes that exploit the host metabolic machineries to meet their biosynthetic demands, making these host pathways potential therapeutic targets. Here, by exploring a lipid library, we show that AM580, a retinoid d
Publikováno v:
Principles of Molecular Medicine ISBN: 9781588292025
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab9f0aa23c31d769834eb056090125dd
https://doi.org/10.1007/978-1-59259-963-9_52
https://doi.org/10.1007/978-1-59259-963-9_52