Small Molecule Screening Identifies HSP90 as a Modifier of RNA Foci in Myotonic Dystrophy Type 1.

Autor: Johnson SJ; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular & Cellular Biology, Baylor College of Medicine, Houston, Texas, USA., Johnson HL; Department of Molecular & Cellular Biology, Baylor College of Medicine, Houston, Texas, USA., Powell RT; Department of Translational Medical Science, Institute of Biosciences and Technology, Texas A&M University, Houston, Texas, USA., Stephan C; Department of Translational Medical Science, Institute of Biosciences and Technology, Texas A&M University, Houston, Texas, USA., Stossi F; Department of Molecular & Cellular Biology, Baylor College of Medicine, Houston, Texas, USA., Cooper TA; Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular & Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.; Department of Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, Texas, USA.

Publikováno v: Molecular and cellular biology [Mol Cell Biol] 2024 Oct 17, pp. 1-13. Date of Electronic Publication: 2024 Oct 17.

Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers.

Autor: Sundaram L; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Computer Science, Stanford University, Stanford, CA, USA.; Illumina AI laboratory, Illumina Inc, Foster City, CA, USA.; NVIDIA Bio Research, NVIDIA, Santa Clara, CA, USA., Kumar A; Illumina AI laboratory, Illumina Inc, Foster City, CA, USA., Zatzman M; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Salcedo A; Illumina AI laboratory, Illumina Inc, Foster City, CA, USA., Ravindra N; Illumina AI laboratory, Illumina Inc, Foster City, CA, USA., Shams S; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA., Louie BH; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA., Bagdatli ST; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA., Myers MA; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sarmashghi S; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Choi HY; Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.; Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA., Choi WY; UTHSC Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN, USA., Yost KE; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA., Zhao Y; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA., Granja JM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Hinoue T; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Hayes DN; Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.; Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.; UTHSC Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN, USA., Cherniack A; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Felau I; National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Choudhry H; Department of Biochemistry, Faculty of Science, Cancer and Mutagenesis Unit, King Fahd Center for Medical Research, King Abdulaziz University, Jeddah, Saudi Arabia., Zenklusen JC; National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA., Farh KK; Illumina AI laboratory, Illumina Inc, Foster City, CA, USA., McPherson A; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Curtis C; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Laird PW; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Demchok JA; Center for Cancer Genomics, National Cancer Institute, Bethesda, MD 20892, USA., Yang L; Center for Cancer Genomics, National Cancer Institute, Bethesda, MD 20892, USA., Tarnuzzer R; Center for Cancer Genomics, National Cancer Institute, Bethesda, MD 20892, USA., Caesar-Johnson SJ; Center for Cancer Genomics, National Cancer Institute, Bethesda, MD 20892, USA., Wang Z; Center for Biomedical Informatics and Information Technology, National Cancer Institute, NIH, 9609 Medical Center Drive, Rockville, MD 20850, USA., Doane AS; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065, USA., Khurana E; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA., Castro MAA; Bioinformatics and Systems Biology Laboratory, Federal University of Paraná, Curitiba 81520-260, Brazil., Lazar AJ; Departments of Pathology & Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Broom BM; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Weinstein JN; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030., Akbani R; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Kumar SV; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Raphael BJ; Department of Computer Science, Princeton University, 35 Olden Street, Princeton, NJ 08540., Wong CK; Biomolecular Engineering Department, School of Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA., Stuart JM; Biomolecular Engineering Department, School of Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA., Safavi R; Biomolecular Engineering Department, School of Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA., Benz CC; Buck Institute for Research on Aging, Novato, CA 94945, USA., Johnson BK; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Kyi C; Center for Cancer Genomics, National Cancer Institute, Bethesda, MD 20892, USA., Shen H; Center for Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Corces MR; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA.; Department of Neurology, University of California San Francisco, San Francisco, CA, USA., Chang HY; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, Stanford University, School of Medicine, Stanford, CA, USA., Greenleaf WJ; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA.; Department of Applied Physics, Stanford University, Stanford, CA, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2024 Sep 06; Vol. 385 (6713), pp. eadk9217. Date of Electronic Publication: 2024 Sep 06.

TRAMP assembly alters the conformation and RNA binding of Mtr4 and Trf4-Air2.

Autor: Denson JM, Zhang N, Ball D, Thompson K, Johnson SJ, D'Arcy S

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 25. Date of Electronic Publication: 2024 Jul 25.

Are energy drinks unique mixers in terms of their effects on alcohol consumption and negative alcohol-related consequences?

Autor: Johnson SJ, Alford C, Stewart K, Verster JC

Publikováno v: International Journal of General Medicine, Vol Volume 11, Pp 15-23 (2018)

Sean J Johnson,1 Chris Alford,1 Karina Stewart,2 Joris C Verster3–5 1Department of Health and Social Sciences, Psychological Sciences Research Group, University of the West of England, 2Department of Applied Sciences, Biomedical and Analytical Scie

Externí odkaz: https://doaj.org/article/6b97b81bb6f14f0a84ba80dd83f3950e

Human Stem Cell-Derived Cardiomyocytes Integrate Into the Heart of Monkeys With Right Ventricular Pressure Overload.

Autor: Scholz J; Department of Comparative Medicine, Mayo Clinic, Rochester, MN, USA., Secreto FJ; Department of Medicine, Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA., Wobig J; Todd and Karen Wanek Family Program for HLHS at Mayo Clinic, Rochester, MN, USA., Kurian J; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Hagen C; Todd and Karen Wanek Family Program for HLHS at Mayo Clinic, Rochester, MN, USA., Zinnen A; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Vu D; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Johnson SJ; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Cetta F; Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., Qureshi Y; Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA., Reams R; StageBio, Mt. Jackson, VA, USA., Cannon B; Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.; Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Heyer CM; Todd and Karen Wanek Family Program for HLHS at Mayo Clinic, Rochester, MN, USA., Chang M; HeartWorks, Rochester, MN, USA., Fadra N; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Coonen J; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Simmons HA; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Mejia A; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Hayes JM; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Basu P; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Capuano S; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Bondarenko V; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Metzger JM; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA., Nelson TJ; Department of Medicine, Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA.; Todd and Karen Wanek Family Program for HLHS at Mayo Clinic, Rochester, MN, USA.; Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.; Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Emborg ME; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA.; Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.

Publikováno v: Cell transplantation [Cell Transplant] 2024 Jan-Dec; Vol. 33, pp. 9636897241290367.