Estrogen Therapy Induces Receptor-Dependent DNA Damage Enhanced by PARP Inhibition in ER+ Breast Cancer.

Autor: Traphagen NA; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Schwartz GN; Department of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Tau S; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Roberts AM; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Jiang A; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Hosford SR; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Marotti JD; Department of Pathology and Laboratory Medicine, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Goen AE; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Romo BA; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Johnson AL; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Duffy EK; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Demidenko E; Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Heverly P; Champions Oncology Inc., Rockville, Maryland., Mosesson Y; Champions Oncology Inc., Rockville, Maryland., Soucy SM; Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.; Center for Quantitative Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Kolling F; Center for Quantitative Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Miller TW; Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Sep 15; Vol. 29 (18), pp. 3717-3728.