Exploring P2X7 receptor antagonism as a therapeutic target for neuroprotection in an hiPSC motor neuron model.

Autor: Johns AE; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Taga A; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Charalampopoulou A; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Gross SK; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Rust K; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., McCray BA; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Sullivan JM; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Maragakis NJ; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States.

Publikováno v: Stem cells translational medicine [Stem Cells Transl Med] 2024 Oct 17. Date of Electronic Publication: 2024 Oct 17.

Class I/IIb-Selective HDAC Inhibitor Exhibits Oral Bioavailability and Therapeutic Efficacy in Acute Myeloid Leukemia.

Autor: Shouksmith AE; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Gawel JM; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Nawar N; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Sina D; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Raouf YS; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Bukhari S; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., He L; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Johns AE; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Manaswiyoungkul P; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Olaoye OO; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Cabral AD; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Sedighi A; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., de Araujo ED; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Gunning PT; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Dec 13; Vol. 11 (1), pp. 56-64. Date of Electronic Publication: 2019 Dec 13 (Print Publication: 2020).

Metabolic and ultrastructural characterization of guinea pig alveolar type II cells isolated by centrifugal elutriation.

Autor: Sikpi MO, Nair CR, Johns AE, Das SK

Publikováno v: Biochimica et biophysica acta [Biochim Biophys Acta] 1986 Jun 11; Vol. 877 (1), pp. 20-30.