Exploring P2X7 receptor antagonism as a therapeutic target for neuroprotection in an hiPSC motor neuron model.

Autor: Johns AE; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Taga A; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Charalampopoulou A; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Gross SK; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Rust K; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., McCray BA; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Sullivan JM; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States., Maragakis NJ; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States.

Publikováno v: Stem cells translational medicine [Stem Cells Transl Med] 2024 Oct 17. Date of Electronic Publication: 2024 Oct 17.

Class I/IIb-Selective HDAC Inhibitor Exhibits Oral Bioavailability and Therapeutic Efficacy in Acute Myeloid Leukemia.

Autor: Shouksmith AE; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Gawel JM; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Nawar N; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Sina D; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Raouf YS; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Bukhari S; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., He L; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Johns AE; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Manaswiyoungkul P; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Olaoye OO; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Cabral AD; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Sedighi A; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., de Araujo ED; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada., Gunning PT; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Dec 13; Vol. 11 (1), pp. 56-64. Date of Electronic Publication: 2019 Dec 13 (Print Publication: 2020).

The Aspergillus fumigatus dihydroxyacid dehydratase Ilv3A/IlvC is required for full virulence.

Autor: Oliver JD; F2G Limited, Manchester, United Kingdom., Kaye SJ, Tuckwell D, Johns AE, Macdonald DA, Livermore J, Warn PA, Birch M, Bromley MJ

Publikováno v: PloS one [PLoS One] 2012; Vol. 7 (9), pp. e43559. Date of Electronic Publication: 2012 Sep 18.

Effects of branched-chain amino acids on Shiraia perylenequinone production in mycelium cultures.

Autor: Shen, Wen Hao¹ (AUTHOR), Cong, Rui Peng¹ (AUTHOR), Li, Xin Ping¹ (AUTHOR), Huang, Qun Yan¹ (AUTHOR), Zheng, Li Ping² (AUTHOR), Wang, Jian Wen¹ (AUTHOR) jwwang@suda.edu.cn

Publikováno v: Microbial Cell Factories. 3/24/2023, Vol. 22 Issue 1, p1-15. 15p.

In Vitro Models of Amyotrophic Lateral Sclerosis.

Autor: Zhou, Lijun, Chen, Wenzhi, Jiang, Shishi, Xu, Renshi

Publikováno v: Cellular & Molecular Neurobiology; Nov2023, Vol. 43 Issue 8, p3783-3799, 17p