Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Johnny Vercouillie"'
Autor:
Oliver C. Kiss, Peter J. H. Scott, Martin Behe, Ivan Penuelas, Jan Passchier, Ana Rey, Marianne Patt, Silvio Aime, Amir Jalilian, Peter Laverman, Zhen Cheng, Alain Faivre Chauvet, Jonathan Engle, Frederik Cleeren, Hua Zhu, Johnny Vercouillie, Michael van Dam, Ming Rong Zhang, Lars Perk, Benjamin Guillet, Francisco Alves
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Background The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biannual highlight commentary to update the readership on trends in the field of radiopharmaceutical development. Main Body This selection of highlights provides
Externí odkaz:
https://doaj.org/article/10468f03ff4e4a0fb2f2efed6a746361
Autor:
Frédéric Boisson, Sophie Serriere, Liji Cao, Sylvie Bodard, Alessandro Pilleri, Lionel Thomas, Giancarlo Sportelli, Johnny Vercouillie, Patrick Emond, Clovis Tauber, Nicola Belcari, Jean-Luc Lefaucheur, David Brasse, Laurent Galineau
Publikováno v:
EJNMMI Physics, Vol 9, Iss 1, Pp 1-14 (2022)
Abstract Background Non-human primates (NHP) are critical in biomedical research to better understand the pathophysiology of diseases and develop new therapies. Based on its translational and longitudinal abilities along with its non-invasiveness, PE
Externí odkaz:
https://doaj.org/article/8916ac3552584ca8a4eca533833a1cd3
Autor:
Anne-Claire Dupont, Nicolas Arlicot, Johnny Vercouillie, Sophie Serrière, Serge Maia, Frédérique Bonnet-Brilhault, Maria-Joao Santiago-Ribeiro
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1127 (2023)
The metabotropic glutamate receptor subtype 5 (mGluR5) is a class C G-protein-coupled receptor (GPCR) that has been implicated in various neuronal processes and, consequently, in several neuropsychiatric or neurodevelopmental disorders. Over the past
Externí odkaz:
https://doaj.org/article/a0ef0e8112ad44b9bbb41668f183fdf8
Autor:
Gert Luurtsema, Verena Pichler, Salvatore Bongarzone, Yann Seimbille, Philip Elsinga, Antony Gee, Johnny Vercouillie
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-16 (2021)
Abstract This guideline on molar activity (Am) and specific activity (As) focusses on small molecules, peptides and macromolecules radiolabelled for diagnostic and therapeutic applications. In this guideline we describe the definition of Am and As, a
Externí odkaz:
https://doaj.org/article/953a9cf69c19427dab8b80a129fd80c2
Autor:
Anne-Claire Dupont, Sophie Serrière, Laurent Barantin, Johnny Vercouillie, Clovis Tauber, Valérie Gissot, Sylvie Bodard, Gabrielle Chicheri, Sylvie Chalon, Pr Frédérique Bonnet-Brilhault, Pr Maria-Joao Santiago-Ribeiro, Nicolas Arlicot
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Altered glutamate signaling is thought to be involved in a myriad of psychiatric disorders. Positron emission tomography (PET) imaging with [18F]FPEB allows assessing dynamic changes in metabotropic glutamate receptor 5 (mGluR5) availability
Externí odkaz:
https://doaj.org/article/4fd6a35337044f71b987943cef746800
Autor:
Christine Vala, Céline Mothes, Gabrielle Chicheri, Pauline Magadur, Gilles Viot, Jean-Bernard Deloye, Serge Maia, Yann Bouvet, Anne-Claire Dupont, Nicolas Arlicot, Denis Guilloteau, Patrick Emond, Johnny Vercouillie
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-14 (2020)
Abstract Background Fluorine labelled 8-((E)-4-fluoro-but-2-enyl)-3β-p-tolyl-8-aza-bicyclo[3.2.1]octane-2β-carboxylic acid methyl ester ([18F]LBT999) is a selective radioligand for the in vivo neuroimaging and quantification of the dopamine transpo
Externí odkaz:
https://doaj.org/article/cc76bd2c9b0b41288b696111b1292997
Autor:
Daniela Perani, Leonardo Iaccarino, Andreas H. Jacobs, IMBI Brain Imaging Working Group, Adriaan A. Lammertsma, Agneta Nordberg, Albert D. Windhorst, Alexander Gerhard, Alexandra Winkeler, Anthony Gee, Bertrand Kuhnast, Christer Halldin, David Brooks, Elena Rodriguez‐Vieitez, Federico E. Turkheimer, Francisco López‐Picón, Gitte M. Knudsen, Johnny Vercouillie, Juha O. Rinne, Karl Herholz, Koen Van Laere, Andrea Varrone, Marie Joao Santiago‐Ribeiro, Matthias M. Herth, Michael A. Carroll, Sylvie Chalon, Michel Bottlaender, Oskar Hansson, Paul Edison, Rainer Hinz, Ronald Boellaard, Rosa Maria Moresco, Sabina Pappata
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 327-332 (2019)
Abstract Introduction A rapid transition from a clinical‐based classification to a pathology‐based classification of neurodegenerative conditions, largely promoted by the increasing availability of imaging biomarkers, is emerging. The Framework f
Externí odkaz:
https://doaj.org/article/50bd95b6267e48ed9f70a0858de39d47
Autor:
Simon Garnier, Kévin Brugemann, Agnieszka Zak, Johnny Vercouillie, Marie Potier-Cartereau, Mathieu Marchivie, Sylvain Routier, Frédéric Buron
Publikováno v:
Catalysts, Vol 12, Iss 8, p 828 (2022)
The first access to N-1, N-4 disubstituted pyrrolo[2,3-d][1,2,3]triazoles is reported. The series were generated using a “one-pot” MCR, leading to a single regioisomer of the attempted heteroaromatic skeleton in good yields. Next, the functionali
Externí odkaz:
https://doaj.org/article/ea7b756973de4a7fa346a185b5e0749e
Autor:
Jonathan Elie, Johnny Vercouillie, Nicolas Arlicot, Lucas Lemaire, Rudy Bidault, Sylvie Bodard, Christel Hosselet, Jean-Bernard Deloye, Sylvie Chalon, Patrick Emond, Denis Guilloteau, Frédéric Buron, Sylvain Routier
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1-7 (2019)
A series of novel derivatives exhibiting high affinity and selectivity towards the COX-2 enzyme in the (aza) indazole series was developed. A short synthetic route involving a bromination/arylation sequence under microwave irradiation and direct C–
Externí odkaz:
https://doaj.org/article/e9cfd14b1cb34e65971969a050ec7b00
Autor:
Maria-Joao Ribeiro, Johnny Vercouillie, Nicolas Arlicot, Clovis Tauber, Valérie Gissot, Karl Mondon, Laurent Barantin, Jean-Philippe Cottier, Serge Maia, Jean-Bernard Deloye, Patrick Emond, Denis Guilloteau
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Purpose: The density of the neuronal dopamine transporter (DAT) is directly correlated with the presynaptic dopaminergic system injury. In a first study, we evaluated the brain distribution and kinetics of [18F]LBT-999, a DAT PET radioligand, in a gr
Externí odkaz:
https://doaj.org/article/3b7e621efc8e41288c0d9972cc466b78