Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Johnny S-H Kwan"'
Autor:
Bonan Chen, Xiaoli Liu, Peiyao Yu, Fuda Xie, Johnny S. H. Kwan, Wai Nok Chan, Canbin Fang, Jinglin Zhang, Alvin H. K. Cheung, Chit Chow, Gloria W. M. Leung, Kam Tong Leung, Shihua Shi, Bin Zhang, Shouyu Wang, Dazhi Xu, Kaili Fu, Chi Chun Wong, William K. K. Wu, Michael W. Y. Chan, Patrick M. K. Tang, Chi Man Tsang, Kwok Wai Lo, Gary M. K. Tse, Jun Yu, Ka Fai To, Wei Kang
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 11, Pp n/a-n/a (2023)
Abstract Background Gastric cancer (GC) is one of the most common tumours in East Asia countries and is associated with Helicobacter pylori infection. H. pylori utilizes virulence factors, CagA and VacA, to up‐regulate pro‐inflammatory cytokines
Externí odkaz:
https://doaj.org/article/7bfa61a822b64b09a39959da5d928f18
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The genomic characterisation of nasopharyngeal carcinoma (NPC) remains crucial. Here, the authors perform whole-genome sequencing for 70 NPCs with EBV gene expression, report the somatic alterations and EBV-mediated effects converging on NF-κB activ
Externí odkaz:
https://doaj.org/article/84b65b92c11446b886dec64811b68199
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f4c5624de0d740c496d631d66856f4cf
Autor:
Jason Y. K. Chan, Vivian Wai Yan Lui, Sau Dan Lee, Trevor J. Pugh, Brigette B.Y. Ma, Yvonne Y. Y. Or, Kwok Wai Lo, Lee Fah Yap, Yuk-Yu Chan, Edwin P. Hui, Fei-Fei Liu, Yuchen Liu, Michael K. F. Mak, Chit Chow, Pui Kei Siu, Anthony T.C. Chan, Samah El Ghamrasni, Chi Man Tsang, Grace Tin-Yun Chung, Johnny S. H. Kwan, Ian C. Paterson, Jeff Bruce, Man Wu, C. Andrew van Hasselt, Kevin Y. Yip, Christopher W. Dawson, Sai Wah Tsao, John K. S. Woo, Sharmila Velapasamy, Ka Fai To, Lawrence S. Young, Stephenie Prokopec
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Interplay between EBV infection and acquired genetic alterations during nasopharyngeal carcinoma (NPC) development remains vague. Here we report a comprehensive genomic analysis of 70 NPCs, combining whole-genome sequencing (WGS) of microdissected tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ad84f9ebb6daaa0d0217af37e916b1
https://doaj.org/article/84b65b92c11446b886dec64811b68199
https://doaj.org/article/84b65b92c11446b886dec64811b68199
Autor:
Zhen-Yu Zhang, Hong Chen, Aden Ka-Yin Chan, Houtan Noushmehr, Ho Keung Ng, Gabriel Chun-Hei Wong, Queenie Hoi-Wing Wong, Xianzhi Liu, Danny Tat Ming Chan, Kay Ka-Wai Li, Johnny S. H. Kwan, Weiwei Wang, Wencai Li, Tathiane M. Malta, Yura Grabovska, Chris Jones, Queenie Junqi Huang, Ying Mao, Zhifeng Shi
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
WHO 2016 classified glioblastomas into IDH-mutant and IDH-wildtype with the former having a better prognosis but there was no study on IDH-mutant primary glioblastomas only, as previous series included secondary glioblastomas. We recruited a series o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef8e8feb03cfd5a96917d6b18f32915
https://doi.org/10.1038/s41379-021-00778-x
https://doi.org/10.1038/s41379-021-00778-x
Autor:
Yan Shao, Sui-Ting Lai, Chit Chow, Julia Y. Tsang, Ivan K. Poon, Gary Tse, Yun-Bi Ni, Ka-Ho Shea, Johnny S. H. Kwan
Publikováno v:
Breast Cancer Research and Treatment. 187:339-347
Purpose SETD2 is one of the key epigenetic regulatory genes involved in histone modifications. Its alterations were potentially oncogenic and commonly found in cancers. Interestingly, SETD2 is one of the most frequent mutated genes found exclusively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd59acae2c748da4d6319fb84f8ab18d
https://doi.org/10.1007/s10549-021-06181-z
https://doi.org/10.1007/s10549-021-06181-z
Autor:
Jacqueline Ho Sze Lee, Ronald C. K. Chan, Johnny S. H. Kwan, Suet Ying Yeung, Ka Fai To, Joshua J. X. Li, Tat San Lau, So Fan Yim, Joseph Kwong, Chit Chow
Publikováno v:
Biomedicines, Vol 9, Iss 1385, p 1385 (2021)
Biomedicines
Volume 9
Issue 10
Biomedicines
Volume 9
Issue 10
To investigate the role of DNA mismatch repair status (MMR) in survival of endometrioid endometrial cancer in Hong Kong Chinese women and its correlation to clinical prognostic factors, 238 patients with endometrioid endometrial cancer were included.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e3b79e76f69003848712cf55aed4fa
https://www.mdpi.com/2227-9059/9/10/1385
https://www.mdpi.com/2227-9059/9/10/1385
Autor:
Zhongyu Zhang, Johnny S. H. Kwan, Carlos Lam, Clarence Edward Choi, Jun Huang, Charles Wang Wai Ng, Gang Wu, Yuchen Su
Publikováno v:
Canadian Geotechnical Journal. 56:1251-1260
A large amount of waste glass is generated every year and contributes significantly to landfills. Large-scale physical model tests were carried out to study the dynamic response of recycled crushed glass (RCG) contained in gabion baskets and its perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da567f163586e71b556ed9024c266e7f
https://doi.org/10.1139/cgj-2018-0200
https://doi.org/10.1139/cgj-2018-0200
Autor:
Johnny S. H. Kwan, Qisheng Tang, Yifeng Bao, Ying Mao, Hong Chen, Zhifeng Shi, Rui Ryan Yang, Abudumijiti Aibaidula, Ho Keung Ng, Kay Ka-Wai Li
Publikováno v:
Brain Pathol
Giant cell glioblastoma (gcGBM) is a rare histological variant of GBM, accounting for about 1% of all GBM. The prognosis is poor generally though gcGBM does slightly better than the other IDH‐wild‐type GBM. Because of the rarity of the cases, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f9baa37163eddbf9b855924fe08d3f
https://doi.org/10.1111/bpa.12720
https://doi.org/10.1111/bpa.12720
Autor:
Miao-Xin Li, Johnny S H Kwan, Su-Ying Bao, Wanling Yang, Shu-Leong Ho, Yong-Qiang Song, Pak C Sham
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003143 (2013)
Exome sequencing is becoming a standard tool for mapping Mendelian disease-causing (or pathogenic) non-synonymous single nucleotide variants (nsSNVs). Minor allele frequency (MAF) filtering approach and functional prediction methods are commonly used
Externí odkaz:
https://doaj.org/article/db49c874b02f4428a25ab35a66e93a19