Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Johnny Krasinkiewicz"'
Autor:
Nathan VanderVeen, Christopher Paran, Ashley Appelhans, Johnny Krasinkiewicz, Rosemary Lemons, Henry Appelman, Robert Doherty, Donna Palmer, Philip Ng, Pedro R Lowenstein, Maria G Castro
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
We developed a combined conditional cytotoxic, i.e., herpes simplex type 1-thymidine kinase (TK), plus immune-stimulatory, i.e., fms-like tyrosine kinase ligand-3–mediated gene therapy for glioblastoma multiforme (GBM). Therapeutic transgenes were
Externí odkaz:
https://doaj.org/article/b7ac2b59d5f14fbf898b4e0597c1b16f
Autor:
Liliana M. Lacayo, Johnny Krasinkiewicz, Catherine Farrokhi, Mariana Puntel, Maria G. Castro, Kyle R. Kelson, Ghulam Muhammad A.K.M., Sukhpreet Kaur, Nathan VanderVeen, Philip Ng, Sean Kennedy, Robert N. Pechnick, Christopher Paran, Pedro R. Lowenstein, Ashley Appelhans, Kurt M. Kroeger, Alireza Salem, Donna Palmer, Chunyan Liu
Publikováno v:
Toxicology and Applied Pharmacology. 268:318-330
Adenoviral vectors (Ads) are promising gene delivery vehicles due to their high transduction efficiency; however, their clinical usefulness has been hampered by their immunogenicity and the presence of anti-Ad immunity in humans. We reported the effi
Autor:
Christopher Paran, Philip Ng, Ashley Appelhans, Robert Doherty, Johnny Krasinkiewicz, Rosemary M. Lemons, Henry D. Appelman, Maria G. Castro, Pedro R. Lowenstein, Donna Palmer, Nathan VanderVeen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
We developed a combined conditional cytotoxic, i.e., herpes simplex type 1-thymidine kinase (TK), plus immune-stimulatory, i.e., fms-like tyrosine kinase ligand-3–mediated gene therapy for glioblastoma multiforme (GBM). Therapeutic transgenes were
Autor:
Neha Kamran, David O. Ferguson, Carl Koschmann, Vera Gorbunova, Soyeon Roh, Felipe J Nunez, Alan K. Meeker, Marta Dzaman, Johnny Krasinkiewicz, Youping Li, Daniel Thomas, Pedro R. Lowenstein, Rosie Lemons, Maria G. Castro, Lili Zhao, Alexandra Calinescu, Flor M. Mendez
Publikováno v:
Neuro-Oncology. 17:iii10-iii11
Pediatric glioblastoma (GBM) remains one of the most difficult childhood tumors to treat. ATRX is a histone chaperone protein that is mutated primarily in pediatric patients with GBM and younger adults with secondary GBM. No previous animal model has
Autor:
Carl Koschmann, Soyeon Roh, Felipe J Nunez, Daniel Thomas, Marta Dzaman, David O. Ferguson, Rosie Lemons, Pedro R. Lowenstein, Maria G. Castro, Neha Kamran, Alexandra Calinescu, Flor M. Mendez, Johnny Krasinkiewicz
Publikováno v:
Cancer Research. 75:3009-3009
Pediatric Glioblastoma (GBM) remains one of the most difficult childhood tumors to treat, and most children with this diagnosis will not survive longer than two years. ATRX is a histone chaperone protein that is mutated primarily in pediatric patient