Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Johnny Cheuk-on Tang"'
Autor:
Zhongguo Zhou, Can Tao, Jianting Li, Johnny Cheuk-on Tang, Albert Sun-chi Chan, Yuanyuan Zhou
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chimeric antigen receptor T cell (CAR-T) therapy is novel tumor immunotherapy that enables autologous T to express synthetic receptors to specifically recognize the surface tumor-associated antigens for exerting subsequent antitumor effects, and elim
Externí odkaz:
https://doaj.org/article/ba86be926fec4392931165044e45861e
Autor:
Yuanyuan Zhou, Po-yee Chung, Jessica Yuen-wuen Ma, Alfred King-yin Lam, Simon Law, Kwok-wah Chan, Albert Sun-chi Chan, Xingshu Li, Kim-hung Lam, Chung-hin Chui, Johnny Cheuk-on Tang
Publikováno v:
Biology, Vol 8, Iss 4, p 75 (2019)
Multidrug resistance (MDR) is one of conventional cancer chemotherapy’s limitations. Our group previously synthesized a series of quinoline-based compounds in an attempt to identify novel anticancer agents. With a molecular docking analysis, the no
Externí odkaz:
https://doaj.org/article/80855663c84e4553b34ddc49428f9c9d
Autor:
Maria Li Lung, Eric J. Stanbridge, Johnny Cheuk On Tang, Sai Wah Tsao, Eugene R. Zabarovsky, Gopesh Srivastava, Simon Law, Yue Cheng, Josephine Mun Yee Ko, Fung Mei Kwong, Kwok Wah Chan, Suneel S. Apte, Arthur Kwok Leung Cheung, Hong Lok Lung, Paulisally Hau Yi Lo
ADAMTS metalloprotease family member ADAMTS9 maps to 3p14.2 and shows significant associations with the aerodigestive tract cancers esophageal squamous cell carcinoma (ESCC) and nasopharyngeal carcinoma (NPC). However, the functional impact of ADAMTS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c7fd7d14881a3daa4a380e305d61b7
https://doi.org/10.1158/0008-5472.c.6500628.v1
https://doi.org/10.1158/0008-5472.c.6500628.v1
Autor:
Maria Li Lung, Eric J. Stanbridge, Johnny Cheuk On Tang, Sai Wah Tsao, Eugene R. Zabarovsky, Gopesh Srivastava, Simon Law, Yue Cheng, Josephine Mun Yee Ko, Fung Mei Kwong, Kwok Wah Chan, Suneel S. Apte, Arthur Kwok Leung Cheung, Hong Lok Lung, Paulisally Hau Yi Lo
Supplementary Table 1 from Extracellular Protease ADAMTS9 Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86e4216e2bb828373cd55a1172ee0ff
https://doi.org/10.1158/0008-5472.22383666.v1
https://doi.org/10.1158/0008-5472.22383666.v1
Autor:
Yuanyuan Zhou, Zhongguo Zhou, Dessy Chan, Po yee Chung, Yongqi Wang, Albert Sun chi Chan, Simon Law, Kim hung Lam, Johnny Cheuk On Tang
Publikováno v:
International Journal of Molecular Sciences, 23 (21)
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13181
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 13181
Quinoline derivatives have been reported to possess a wide range of pharmaceutical activities. Our group previously synthesized a series of quinoline compounds, in which compound 91b1 showed a significant anticancer effect. The purpose of this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c4763afa5f1a5359c9d6710227583f
Publikováno v:
Human Pathology. 87:1-10
Family with sequence similarity 134, member B (FAM134B) is an autophagy regulator of endoplasmic reticulum first discovered to be involved in the pathogenesis of esophageal squamous cell carcinoma (ESCC). The present study examined the functional beh
Autor:
Johnny Cheuk On Tang, Vinod Gopalan, Katherine Ting-Wei Lee, Jelena Vider, Alfred King-Yin Lam
Publikováno v:
Molecular Carcinogenesis. 58:1145-1154
Gene amplified in esophageal cancer 1 (GAEC1) expression and copy number changes are frequently associated with the pathogenesis of colorectal carcinomas. The current study aimed to identify the pathway and its transcriptional factors with which GAEC
Autor:
Ling Huang, Johnny Cheuk On Tang, Baijiao An, Tingting Pan, Xingshu Li, Jinhui Hu, Albert S. C. Chan, Shun Zhang
Publikováno v:
Organic & Biomolecular Chemistry. 16:4701-4714
Inhibition of tubulin polymerization is one of the significant strategies in the treatment of cancer. Inspired by the excellent antitumor activity of EP128495 and the beneficial biological activities of selenium compounds, a series of new selenium-co
Autor:
Yuan Yuan Zhou, Po Yee Chung, Kim Hung Lam, Johnny Cheuk On Tang, Simon Law, Albert S. C. Chan, Alfred King-Yin Lam, Ivan Ho Yuen Pun, Sau Hing Chan, Dessy Chan, Chung Hin Chui
Publikováno v:
Cancer Research and Treatment. 49:219-229
Purpose 83b1 is a novel quinoline derivative that has been shown to inhibit cancer growth in human esophageal squamous cell carcinoma (ESCC). This study was conducted to comprehensively evaluate the cytotoxic effects of 83b1 on a series of ESCC cell
Autor:
Simon Law, Johnny Cheuk On Tang, Vinod Gopalan, Kwok Wah Chan, Suja Pillai, Daniel King Hung Tong, Alfred King-Yin Lam, Farhadul Islam
Publikováno v:
Experimental Cell Research. 348:146-154
Purpose This study aims to examine the expression profiles miR-1288 in oesophageal squamous cell carcinoma (ESCC). The cellular implications and target interactions of ESCC cells following miR-1288 overexpression was also examined. Methods In total,