Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Johnny Cheuk On Tang"'
Autor:
Yuanyuan Zhou, Zhongguo Zhou, Dessy Chan, Po yee Chung, Yongqi Wang, Albert Sun chi Chan, Simon Law, Kim hung Lam, Johnny Cheuk On Tang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13181 (2022)
Quinoline derivatives have been reported to possess a wide range of pharmaceutical activities. Our group previously synthesized a series of quinoline compounds, in which compound 91b1 showed a significant anticancer effect. The purpose of this study
Externí odkaz:
https://doaj.org/article/384bc1b3af204d0983562bdff5f5e625
Autor:
Po Yee Chung, Pik Ling Lam, Yuanyuan Zhou, Jessica Gasparello, Alessia Finotti, Adriana Chilin, Giovanni Marzaro, Roberto Gambari, Zhaoxiang Bian, Wai Ming Kwok, Wai Yeung Wong, Xi Wang, Alfred King-yin Lam, Albert Sun-chi Chan, Xingshu Li, Jessica Yuen Wuen Ma, Chung Hin Chui, Kim Hung Lam, Johnny Cheuk On Tang
Publikováno v:
Cells, Vol 7, Iss 10, p 177 (2018)
Quinoline core has been shown to possess a promising role in the development of anticancer agents. However, the correlation between its broad spectrum of bioactivity and the underlying mechanism of actions is poorly understood. The present study, wit
Externí odkaz:
https://doaj.org/article/59770782c46445f1b5f2921848fe3c86
Autor:
Dessy Chan, Yuanyuan Zhou, Chung Hin Chui, Kim Hung Lam, Simon Law, Albert Sun-chi Chan, Xingshu Li, Alfred King-yin Lam, Johnny Cheuk On Tang
Publikováno v:
Cells, Vol 7, Iss 10, p 143 (2018)
Cisplatin (CDDP) is one of the front-line chemotherapeutic drugs used in the treatment of esophageal squamous cell carcinoma (ESCC). Occurrence of resistance to CDDP has become one of the main challenges in cancer therapy. In this study, the gene exp
Externí odkaz:
https://doaj.org/article/da7a74cc76b04b4d946f483c0b168183
Autor:
Maria Li Lung, Eric J. Stanbridge, Johnny Cheuk On Tang, Sai Wah Tsao, Eugene R. Zabarovsky, Gopesh Srivastava, Simon Law, Yue Cheng, Josephine Mun Yee Ko, Fung Mei Kwong, Kwok Wah Chan, Suneel S. Apte, Arthur Kwok Leung Cheung, Hong Lok Lung, Paulisally Hau Yi Lo
ADAMTS metalloprotease family member ADAMTS9 maps to 3p14.2 and shows significant associations with the aerodigestive tract cancers esophageal squamous cell carcinoma (ESCC) and nasopharyngeal carcinoma (NPC). However, the functional impact of ADAMTS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c7fd7d14881a3daa4a380e305d61b7
https://doi.org/10.1158/0008-5472.c.6500628.v1
https://doi.org/10.1158/0008-5472.c.6500628.v1
Autor:
Maria Li Lung, Eric J. Stanbridge, Johnny Cheuk On Tang, Sai Wah Tsao, Eugene R. Zabarovsky, Gopesh Srivastava, Simon Law, Yue Cheng, Josephine Mun Yee Ko, Fung Mei Kwong, Kwok Wah Chan, Suneel S. Apte, Arthur Kwok Leung Cheung, Hong Lok Lung, Paulisally Hau Yi Lo
Supplementary Table 1 from Extracellular Protease ADAMTS9 Suppresses Esophageal and Nasopharyngeal Carcinoma Tumor Formation by Inhibiting Angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86e4216e2bb828373cd55a1172ee0ff
https://doi.org/10.1158/0008-5472.22383666.v1
https://doi.org/10.1158/0008-5472.22383666.v1
Autor:
Zhongguo Zhou, Can Tao, Jianting Li, Johnny Cheuk-on Tang, Albert Sun-chi Chan, Yuanyuan Zhou
Publikováno v:
Frontiers in Immunology. 13
Chimeric antigen receptor T cell (CAR-T) therapy is novel tumor immunotherapy that enables autologous T to express synthetic receptors to specifically recognize the surface tumor-associated antigens for exerting subsequent antitumor effects, and elim
Publikováno v:
Human Pathology. 87:1-10
Family with sequence similarity 134, member B (FAM134B) is an autophagy regulator of endoplasmic reticulum first discovered to be involved in the pathogenesis of esophageal squamous cell carcinoma (ESCC). The present study examined the functional beh
Autor:
Johnny Cheuk On Tang, Vinod Gopalan, Katherine Ting-Wei Lee, Jelena Vider, Alfred King-Yin Lam
Publikováno v:
Molecular Carcinogenesis. 58:1145-1154
Gene amplified in esophageal cancer 1 (GAEC1) expression and copy number changes are frequently associated with the pathogenesis of colorectal carcinomas. The current study aimed to identify the pathway and its transcriptional factors with which GAEC
Autor:
Ling Huang, Johnny Cheuk On Tang, Baijiao An, Tingting Pan, Xingshu Li, Jinhui Hu, Albert S. C. Chan, Shun Zhang
Publikováno v:
Organic & Biomolecular Chemistry. 16:4701-4714
Inhibition of tubulin polymerization is one of the significant strategies in the treatment of cancer. Inspired by the excellent antitumor activity of EP128495 and the beneficial biological activities of selenium compounds, a series of new selenium-co
Autor:
Yuan Yuan Zhou, Po Yee Chung, Kim Hung Lam, Johnny Cheuk On Tang, Simon Law, Albert S. C. Chan, Alfred King-Yin Lam, Ivan Ho Yuen Pun, Sau Hing Chan, Dessy Chan, Chung Hin Chui
Publikováno v:
Cancer Research and Treatment. 49:219-229
Purpose 83b1 is a novel quinoline derivative that has been shown to inhibit cancer growth in human esophageal squamous cell carcinoma (ESCC). This study was conducted to comprehensively evaluate the cytotoxic effects of 83b1 on a series of ESCC cell