Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Johnnie J, Orozco"'
Autor:
Kevin P. Labadie, Adrienne L. Lehnert, Aimee L. Kenoyer, Donald K. Hamlin, Andrew D. Ludwig, Alan F. Utria, Sara K. Daniel, Tara N. Mihailovic, Alexander Prossnitz, Johnnie J. Orozco, Yawen Li, D. Scott Wilbur, Robert S. Miyaoka, James O. Park
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Background Early intrahepatic recurrence is common after surgical resection of hepatocellular carcinoma (HCC) and leads to increased morbidity and mortality. Insensitive and nonspecific diagnostic imaging contributes to EIR and results in mi
Externí odkaz:
https://doaj.org/article/de5efabc7d0b4c4991c791912e3e2374
Autor:
Kevin P. Labadie, Andrew D. Ludwig, Adrienne L. Lehnert, Donald K. Hamlin, Aimee L. Kenoyer, Kevin M. Sullivan, Sara K. Daniel, Tara N. Mihailovic, Jonathan G. Sham, Johnnie J. Orozco, Raymond S. Yeung, Delphine L. Chen, D. Scott Wilbur, Robert S. Miyaoka, James O. Park
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Glypican-3 (GPC3) is a tumor associated antigen expressed by hepatocellular carcinoma (HCC) cells. This preclinical study evaluated the efficacy of a theranostic platform using a GPC3-targeting antibody αGPC3 conjugated to zirconium-89 (89Z
Externí odkaz:
https://doaj.org/article/ddea22e7449b4b418c2f02ca24983fd2
Autor:
George S. Laszlo, Brenda M. Sandmaier, Allie R. Kehret, Johnnie J. Orozco, Donald K. Hamlin, Shannon L. Dexter, Sheryl Y. T. Lim, Frances M. Cole, Jenny Huo, D. Scott Wilbur, Roland B. Walter
Publikováno v:
Leukemia & Lymphoma. :1-5
Autor:
Phuong Vo, Ted A. Gooley, Joseph G. Rajendran, Darrell R. Fisher, Johnnie J. Orozco, Damian J. Green, Ajay K. Gopal, Robyn Haaf, Margaret Nartea, Rainer Storb, Frederick R. Appelbaum, Oliver W. Press, John M. Pagel, Brenda M. Sandmaier
Publikováno v:
Haematologica, Vol 105, Iss 6 (2020)
Outcomes of patients with persistent high-risk leukemia or myelodysplasia prior to allogeneic hematopoietic cell transplantation are dismal. We therefore conducted a phase I trial evaluating the use of CD45-targeted radiotherapy preceding hematopoiet
Externí odkaz:
https://doaj.org/article/5305b45938ed4d9fbd2343bde3761ae8
Autor:
Emily S Ford, William Simmons, Ellora N Karmarkar, Leah H Yoke, Ayodale B Braimah, Johnnie J Orozco, Cristina M Ghiuzeli, Serena Barnhill, Coralynn L Sack, Joshua O Benditt, Pavitra Roychoudhury, Alexander L Greninger, Adrienne E Shapiro, Jennifer L Hammond, James M Rusnak, Mikael Dolsten, Michael Boeckh, Catherine Liu, Guang-Shing Cheng, Lawrence Corey
Publikováno v:
Clinical Infectious Diseases. 76:926-929
A patient with B-cell acute lymphoblastic leukemia (ALL) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had persistent, progressive pneumonia with viremia after 5 months of infection despite monoclonal antibodies, intravenous (IV) r
Autor:
Anna B. Halpern, Megan Othus, Emily M. Huebner, Bart L. Scott, Paul C. Hendrie, Mary-Elizabeth M. Percival, Pamela S. Becker, Heather A. Smith, Vivian G. Oehler, Johnnie J. Orozco, Ryan D. Cassaday, Kelda M. Gardner, Tara L. Chen, Sarah A. Buckley, Kaysey F. Orlowski, Asma Anwar, Elihu H. Estey, Roland B. Walter
Publikováno v:
Haematologica, Vol 104, Iss 4 (2019)
Externí odkaz:
https://doaj.org/article/f4c60eaa187e447a9c5cf66831e4bbbf
Autor:
John M. Pagel, Oliver W. Press, Brenda Sandmaier, Brian G. Till, Ajay K. Gopal, Damian J. Green, K. Dane Wittrup, Kelly D. Orcutt, D. Scott Wilbur, Donald K. Hamlin, Ethan R. Balkin, Darrell R. Fisher, Mark D. Hylarides, Alexandra H. Hernandez, Margaret E. Nartea, Rosario Guel, Shyril O'Steen, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco
Pretargeted radioimmunotherapy (PRIT) has been investigated as a multi-step approach to decrease relapse and toxicity for high-risk acute myeloid leukemia (AML). Relevant factors including endogenous biotin and immunogenicity, however, have limited t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18cb196c04e590eb312858a4d9061fed
https://doi.org/10.1158/1535-7163.c.6542662
https://doi.org/10.1158/1535-7163.c.6542662
Autor:
John M. Pagel, Oliver W. Press, Brenda Sandmaier, Brian G. Till, Ajay K. Gopal, Damian J. Green, K. Dane Wittrup, Kelly D. Orcutt, D. Scott Wilbur, Donald K. Hamlin, Ethan R. Balkin, Darrell R. Fisher, Mark D. Hylarides, Alexandra H. Hernandez, Margaret E. Nartea, Rosario Guel, Shyril O'Steen, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco
Supplementary Materials, Methods and relevant AA sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c057d8965675ca7f790ca8236eb48a
https://doi.org/10.1158/1535-7163.22520518.v1
https://doi.org/10.1158/1535-7163.22520518.v1
Autor:
Oliver W. Press, Brian G. Till, Amelia Waltman, Theodore A. Gooley, Mark D. Hylarides, Darrell R. Fisher, Donald K. Hamlin, D. Scott Wilbur, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco, Ajay K. Gopal, Damian J. Green, Shyril O'Steen
Table S1 presents mouse survival data for in vivo experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1f8931fda4e9dec0f52f77d94c1a28
https://doi.org/10.1158/0008-5472.22414092.v1
https://doi.org/10.1158/0008-5472.22414092.v1
Autor:
Oliver W. Press, K. Dane Wittrup, D. Scott Wilbur, Kelly D. Orcutt, Shyril O'Steen, Brian G. Till, Johnnie J. Orozco, Theodore A. Gooley, Ajay K. Gopal, Mark D. Hylarides, Aimee L. Kenoyer, Sofia H.L. Frost, Darrell R. Fisher, Donald K. Hamlin, Yukang Lin, Shani L. Frayo, Damian J. Green
Figures including: Supplemental Figure 1- Dose finding pharmacokinetics. Supplemental Figure 2- Dose finding tissue biodistribution. Supplemental Figure 3- body weight over time in a therapy study. Supplemental Figure 4- blood counts over time in a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fa9ad6c582f79e53958516ac3c2d49
https://doi.org/10.1158/0008-5472.22413027
https://doi.org/10.1158/0008-5472.22413027