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pro vyhledávání: '"Johnni L. Gullo-Brown"'
Autor:
Dinesh V. Patel, Eric M. Gordon, Robert J. Schmidt, Harold N. Weller, Marian G. Young, Robert Zahler, Mariano Barbacid, Joan M. Carboni, Johnni L. Gullo-Brown, Lisa Hunihan, Carol Ricca, Simon Robinson, Bernd R. Seizinger, Anne V. Tuomari, Veeraswamy Manne
Publikováno v:
Journal of medicinal chemistry. 38(3)
The rational design, synthesis, and biological activity of phosphonyl- and phosphinyl-linked bisubstrate analog inhibitors of the enzyme Ras farnesyl protein transferase (FPT) are described. The design strategy for these bisubstrate inhibitors involv