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pro vyhledávání: '"Johnathon B Schafer"'
Autor:
Thu A. Doan, Tadg S. Forward, Johnathon B. Schafer, Erin D. Lucas, Ira Fleming, Aspen Uecker-Martin, Edgardo Ayala, Jenna J. Guthmiller, Jay R. Hesselberth, Thomas E. Morrison, Beth A. Jirón Tamburini
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Antigens from viruses or immunizations can persist or are archived in lymph node stromal cells such as lymphatic endothelial cells (LEC) and fibroblastic reticular cells (FRC). Here, we find that, during the time frame of antigen archiving,
Externí odkaz:
https://doaj.org/article/c51ada010dc34878b794df452efbd18b
Autor:
Johnathon B. Schafer, Erin D. Lucas, Monika Dzieciatkowska, Tadg Forward, Beth A. Jirón Tamburini
Publikováno v:
Journal of Biological Chemistry. 298:102694
Lymphatic endothelial cells (LECs) comprise lymphatic capillaries and vessels that guide immune cells to lymph nodes (LNs) and form the subcapsular sinus and cortical and medullary lymphatic structures of the LN. During an active immune response, the
Publikováno v:
The Journal of Immunology. 208:52.05-52.05
Programmed death ligand-1 (PD-L1) interaction with PD-1 on T cells limits immune activation to prevent immunopathology in healthy tissues and the development of autoimmunity. While ligation of PD-1 by PD-L1 leads to T cell-intrinsic PD-1 signaling, P