Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Johnathan R. Whetstine"'
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101827- (2022)
Summary: Temporal profiling of DNA replication timing (RT) in combination with chromatin modifications, chromatin accessibility, and gene expression provides new insights into the causal relationships between chromatin and RT during cell cycle. Here,
Externí odkaz:
https://doaj.org/article/e0af9085231640a4accfa42edd6c56cc
Autor:
Tao Zhang, Cheng Ni, Cheng Li, Pan Lu, Dan Chen, Yuanlin Dong, Johnathan R. Whetstine, Yiying Zhang, Zhongcong Xie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Anesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis. Synchronized L4
Externí odkaz:
https://doaj.org/article/e244fd4943fa4df084da1f7ef0b67eec
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101243- (2022)
Summary: Classic approaches to characterizing cell cycle leverage chemicals or altered nucleotide pools, which could impact chromatin states at specific phases of the cell cycle. Such approaches could induce metabolic alterations and/or DNA damage, w
Externí odkaz:
https://doaj.org/article/4ddc0b5d5d1a40be8cfbe06ed3481fd9
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101209- (2022)
Summary: Traditional replication timing (RT) experiments divide S phase into two phases: early and late. However, there is an increasing awareness that variation in RT can occur during the course of S phase and impact our understanding of RT patterns
Externí odkaz:
https://doaj.org/article/3cd212c190fb4d1499a70bc668551300
Autor:
Capucine Van Rechem, Fei Ji, Damayanti Chakraborty, Joshua C. Black, Ruslan I. Sadreyev, Johnathan R. Whetstine
Publikováno v:
Cell Reports, Vol 37, Iss 1, Pp 109799- (2021)
Summary: Replication timing (RT) associates with genome architecture, while having a mixed relationship to histone marks. By profiling replication at high resolution and assessing broad histone marks across the cell cycle at the resolution of RT with
Externí odkaz:
https://doaj.org/article/79163b53410847a98f882dabdaa24e42
Autor:
Johnathan R. Whetstine, Cyril H. Benes, Wilhelm Haas, Susanne Gräslund, Martin J. Aryee, Myriam Boukhali, Joshua C. Black, Capucine Van Rechem
This file contains legends and information about supplemental material.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba8fcd8084545276fe631e177db5774
https://doi.org/10.1158/2159-8290.22530704
https://doi.org/10.1158/2159-8290.22530704
Autor:
Johnathan R. Whetstine, Cyril H. Benes, Wilhelm Haas, Susanne Gräslund, Martin J. Aryee, Myriam Boukhali, Joshua C. Black, Capucine Van Rechem
Supplementary Figure S3. JIB-04 inhibits translation initiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f4bcd6b3a70f9a898886b97a0c6033
https://doi.org/10.1158/2159-8290.22530707
https://doi.org/10.1158/2159-8290.22530707
Autor:
Johnathan R. Whetstine, Cyril H. Benes, David C. Christiani, Brendon Ladd, Paul d. Burrowes, Carlos Donado, Yang Zhao, Patricia Greninger, Joshua C. Black, Capucine Van Rechem
Supplementary Table 2. Lung cell lines homozygotes for KDM4A SNP-A482 are not enriched for mutations that could be linked to sensitivity to PI3K/mTOR inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151e08a5e290808c46b1f493c5057191
https://doi.org/10.1158/2159-8290.22530278.v1
https://doi.org/10.1158/2159-8290.22530278.v1
Autor:
Johnathan R. Whetstine, Ruslan I. Sadreyev, Michael S. Lawrence, Jian Jin, H. Ümit Kaniskan, Anqi Ma, Sweta Mishra, Fei Ji, Capucine Van Rechem, Damayanti Chakraborty, Ran Tang, Thomas L. Clarke
Supplemental Data and legends and tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0246e94f7bedbaf872baa724e5c3b5fe
https://doi.org/10.1158/2159-8290.22535183
https://doi.org/10.1158/2159-8290.22535183
Autor:
Johnathan R. Whetstine, Cyril H. Benes, David C. Christiani, Brendon Ladd, Paul d. Burrowes, Carlos Donado, Yang Zhao, Patricia Greninger, Joshua C. Black, Capucine Van Rechem
Supplementary Figure 3. Rapamycin treatment reduces KDM4A protein levels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0217ed1522568a8100600cc0510e695b
https://doi.org/10.1158/2159-8290.22530287.v1
https://doi.org/10.1158/2159-8290.22530287.v1