Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Johnathan R, Yarbro"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A hallmark of COVID-19 is a hyperinflammatory state associated with severity. Monocytes undergo metabolic reprogramming and produce inflammatory cytokines when stimulated with SARS-CoV-2. We hypothesized that binding by the viral spike protein mediat
Externí odkaz:
https://doaj.org/article/47fb14b898bc40a48c9df3860b4db0bf
Autor:
Brandt D. Pence, Johnathan R. Yarbro
Publikováno v:
Immunity & Ageing, Vol 16, Iss 1, Pp 1-8 (2019)
Abstract Background Inflammaging is a condition of chronic low-grade inflammation due to the aging process and is associated with a variety of chronic diseases. Monocytes are innate immune cells which contribute to inflammation and are dysregulated d
Externí odkaz:
https://doaj.org/article/9585882153b14e289f7198e28ea95e2c
Autor:
Mehdi Chaib, Laura M. Sipe, Johnathan R. Yarbro, Margaret S. Bohm, Brittany R. Counts, Ubaid Tanveer, Ajeeth K. Pingili, Deidre Daria, Tony N. Marion, James A. Carson, Paul G. Thomas, Liza Makowski
Publikováno v:
Cancer Letters. 531:98-108
Autor:
Johnathan R. Yarbro, Brandt D. Pence
Publikováno v:
Exercise Medicine, Vol 2 (2018)
Monocytes are cells of the innate immune system which perform important functions, including inflammatory cytokine production and phagocytosis, and participate in pathogen defense. In aging and disease, monocyte functions are dysregulated, and this d
Externí odkaz:
https://doaj.org/article/0c05f674ce424384b36060cdd209b043
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
A hallmark of COVID-19 is a hyperinflammatory state associated with severity. Monocytes undergo metabolic reprogramming and produce inflammatory cytokines when stimulated with SARS-CoV-2. We hypothesized that binding by the viral spike protein mediat
Autor:
Mehdi, Chaib, Laura M, Sipe, Johnathan R, Yarbro, Margaret S, Bohm, Brittany R, Counts, Ubaid, Tanveer, Ajeeth K, Pingili, Deidre, Daria, Tony N, Marion, James A, Carson, Paul G, Thomas, Liza, Makowski
Publikováno v:
Cancer letters. 531
Myeloid-derived suppressor cells (MDSCs) are an immature innate cell population that expands in pathological conditions such as cancer and suppresses T cells via production of immunosuppressive factors. Conversely, efficient cytotoxic T cell priming
A hallmark of COVID-19 is a hyperinflammatory state that is associated with severity. Various anti-inflammatory therapeutics have shown mixed efficacy in treating COVID-19, and the mechanisms by which hyperinflammation occurs are not well understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7716e3d5cd2c3c79ee63a91320c1417d
https://doi.org/10.1101/2021.05.27.445991
https://doi.org/10.1101/2021.05.27.445991
Publikováno v:
Aging Medicine
Aging Medicine, Vol 4, Iss 1, Pp 47-52 (2021)
Aging Medicine, Vol 4, Iss 1, Pp 47-52 (2021)
Objective Age‐associated decreases in immune functions are precipitated by a variety of mechanisms and affect nearly every immune cell subset. In myeloid cells, aging reduces numbers of phagocytes and impairs their functional abilities, including a
Publikováno v:
Immunometabolism
Aging is a complex process that involves dysfunction on multiple levels, all of which seem to converge on inflammation. Macrophages are intimately involved in initiating and resolving inflammation, and their dysregulation with age is a primary contri
BackgroundImmunosenescence is an age-associated decrease in function of immune cells precipitated by a variety of mechanisms and affecting nearly every immune cell subset. In myeloid cell subsets, aging reduces numbers of phagocytes and impairs their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a93069a3b5f48570a47a515942c2c59