Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Johnathan G. Lyon"'
Autor:
Syed Faaiz Enam, Sajidur Rahman Kader, Nicholas Bodkin, Johnathan G. Lyon, Mark Calhoun, Cesar Azrak, Pooja Munnilal Tiwari, Daryll Vanover, Haichen Wang, Philip J. Santangelo, Ravi Venkat Bellamkonda
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-24 (2020)
Abstract Background Appropriately modulating inflammation after traumatic brain injury (TBI) may prevent disabilities for the millions of those inflicted annually. In TBI, cellular mediators of inflammation, including macrophages and microglia, posse
Externí odkaz:
https://doaj.org/article/12bd5e2f3a6341a8ac7135fd9d2a035c
Autor:
Nalini Mehta, Johnathan G. Lyon, Ketki Patil, Nassir Mokarram, Christine Kim, Ravi V. Bellamkonda
Publikováno v:
Molecular Therapy: Oncolytics, Vol 4, Iss C, Pp 1-17 (2017)
Treatment of aggressive glioblastoma brain tumors is challenging, largely due to diffusion barriers preventing efficient drug dosing to tumors. To overcome these barriers, bacterial carriers that are actively motile and programmed to migrate and loca
Externí odkaz:
https://doaj.org/article/0822e86a2ee242cdb3127b8190d202af
Autor:
Syed Faaiz Enam, Cem Y. Kilic, Jianxi Huang, Brian J. Kang, Reed Chen, Connor S. Tribble, Ekaterina Ilich, Martha I. Betancur, Stephanie J. Blocker, Steven J. Owen, Anne F. Buckley, Johnathan G. Lyon, Ravi V. Bellamkonda
Publikováno v:
Science advances. 8(47)
Novel therapeutic approaches are needed for patients with glioblastoma (GBM) who otherwise have limited options. Here we studied and deployed non-freezing ‘cytostatic’ hypothermia to stunt GBM growth. This contrasts with ablative, cryogenic hypot
Autor:
Todd J. Brinton, Lyn Denend, Paul G. Yock, Johnathan G. Lyon, Douglas S. Rait, Josh Makower, Nassir Mokarram
Publikováno v:
Annals of Biomedical Engineering. 49:1587-1592
Autor:
Nassir Mokarram, Eun Young Park, Johnathan G. Lyon, Ravi V. Bellamkonda, Melissa Alvarado-Velez, Martha I. Betancur, Jennifer Hyunjong Shin
Publikováno v:
Journal of Neuroscience Research
Traumatic brain injury (TBI) by an external physical impact results in compromised brain function via undesired neuronal death. Following the injury, resident and peripheral immune cells, astrocytes, and neural stem cells (NSCs) cooperatively contrib
Autor:
Cesar Azrak, Haichen Wang, Mark Calhoun, Daryll Vanover, Syed Faaiz Enam, Johnathan G. Lyon, Nicholas Bodkin, Philip J. Santangelo, Pooja M. Tiwari, Ravi V. Bellamkonda, Sajidur Rahman Kader
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-24 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
BackgroundAppropriately modulating inflammation after traumatic brain injury (TBI) may prevent disabilities for the millions of those inflicted annually. In TBI, cellular mediators of inflammation, including macrophages and microglia, possess a range
Chronic stimulation of and recording from the brain and brain diseases can require expensive apparatus and tedious cycles of inducing rodents with anesthesia. To resolve this, we have designed and fabricated a low-cost (∼$75 vs. $450) DIY rodent ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59e398cc56c32fd956e85a947949c987
https://doi.org/10.1101/2021.12.16.473031
https://doi.org/10.1101/2021.12.16.473031
Autor:
Syed Faaiz Enam, Johnathan G. Lyon, Melissa Alvarado-Velez, Michelle C. LaPlaca, Nalini Mehta, Ravi V. Bellamkonda
Publikováno v:
Biomaterials. 266
Traumatic brain injury (TBI) triggers multiple biochemical and cellular processes that exacerbate brain tissue damage through a secondary injury. Therapies that prevent or limit the evolution of secondary injury could significantly reduce the neurolo
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-19 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-19 (2019)
Treatment of neuroepithelial cancers remains a daunting clinical challenge, particularly due to an inability to address rampant invasion deep into eloquent regions of the brain. Given the lack of access, and the dispersed nature of brain tumor cells,
Autor:
John Tipton, Nassir Mokarram, Akhil Srinivasan, Jason Chu, Arthur W. English, Ravi V. Bellamkonda, Kyle Dymanus, Johnathan G. Lyon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(26)
Injuries to the peripheral nervous system are major sources of disability and often result in painful neuropathies or the impairment of muscle movement and/or normal sensations. For gaps smaller than 10 mm in rodents, nearly normal functional recover