Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Johnathan D. Ebben"'
Autor:
Michael A. James, E. Bishop, Davin R. Jensen, Johnathan D. Ebben, Donna McAllister, Sunila Pradeep, Pradeep Chaluvally-Raghavan, Deepak Parashar, Anjali Geethadevi, Francis C. Peterson, Brian F. Volkman, Michael B. Dwinell
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-13 (2021)
NPJ Precision Oncology
NPJ Precision Oncology
Recurrence of therapy-resistant tumors is a principal problem in solid tumor oncology, particularly in ovarian cancer. Despite common complete responses to first line, platinum-based therapies, most women with ovarian cancer recur, and eventually, ne
Autor:
Johnathan D. Ebben, Ming You
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 78:288-296
Lung cancer is a clinically difficult disease with rising disease burden around the world. Unfortunately, most lung cancers present at a clinically advanced stage. Of these cancers, many also present with brain metastasis which complicates the clinic
Publikováno v:
Pharmacological Research. 111:422-433
Aging, cancer, and chronic disease have remained at the forefront of basic biological research for decades. Within this context, significant attention has been paid to the role of telomerase, the enzyme responsible for lengthening telomeres, the nucl
Autor:
Katherine J. Zappia, Raman Marwaha, Johnathan D. Ebben, Gabriela Andrade, Imran Iqbal, Orna Alpert
Publikováno v:
Perioperative Psychiatry ISBN: 9783319997735
Approximately four million surgical procedures are performed in children annually ranging from elective to life-saving surgeries. This chapter focuses on four common psychiatric conditions in the perioperative period: anxiety, depression, delirium, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::828c3c31b86d020474bee2110e065d92
https://doi.org/10.1007/978-3-319-99774-2_15
https://doi.org/10.1007/978-3-319-99774-2_15
Autor:
Andreas M. Beyer, Laura E Norwood Toro, R. Blake Hill, Said H. Audi, Daling Zhu, Meetha Medhora, Matthew J. Durand, Johnathan D. Ebben, Elizabeth R. Jacobs, Anne V. Clough, Cui Ma, Maia Terashvili
Objective— We explored mechanisms that alter mitochondrial structure and function in pulmonary endothelial cells (PEC) function after hyperoxia. Approach and Results— Mitochondrial structures of PECs exposed to hyperoxia or normoxia were visualiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a077a4b035e1479d463457b899d3b4cc
https://europepmc.org/articles/PMC5823793/
https://europepmc.org/articles/PMC5823793/
Publikováno v:
Molecular Carcinogenesis. 55:1517-1525
The ability to prevent disease is the holy grail of medicine. For decades, efforts have been made to extend the successes seen with vaccination against infectious diseases to cancer. In some instances, preventive vaccination against viruses (prototyp
Publikováno v:
Developmental Dynamics. 236:3297-3308
Recently, a subpopulation of cells highly efficient in tumor initiation and growth has been isolated from brain tumors. Of interest, these brain tumor initiating cells exhibit many stem-like properties, including self-renewal, extended proliferation,
Publikováno v:
Hypertension. 66
Rationale: The contributions of nuclear telomerase activity to cardiovascular protection we have previously described are not defined. We used a novel inhibitor of nuclear telomerase activity (nucTERT I) to test the hypothesis that nuclear telomerase
Publikováno v:
World neurosurgery. 76(3-4)
Induced pluripotent stem (iPS) cell technology has enormous potential to advance medical therapy by personalizing regenerative medicine and creating novel human disease models for research and therapeutic testing. Before this technology is broadly us
Autor:
Michael Zorniak, Raman G Kutty, Daniel M. Treisman, Johnathan D. Ebben, Paul A. Clark, John S. Kuo
Publikováno v:
Expert opinion on therapeutic targets. 14(6)
Cancer is the second leading cause of death in the United States, and therefore remains a central focus of modern medical research. Accumulating evidence supports a 'cancer stem cell' (CSC) model - where cancer growth and/or recurrence is driven by a