Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Johnathan A. Hopp"'
Autor:
Johnathan A. Hopp, Martin S. Obin, A. Bohm, Bruce Y. Lee, Rehwa H. Lee, Allen Taylor, Vadim Y. Arshavsky, Rachelle Gaudet, Barry M. Willardson, Gretchen Meinke
Publikováno v:
Journal of Biological Chemistry. 277:44566-44575
G proteins (Gαβγ) are essential signaling molecules, which dissociate into Gα and Gβγ upon activation by heptahelical membrane receptors. We have identified the βγ subunit complex of the photoreceptor-specific G protein, transducin (T), as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c5a7f7ab6e88990786195391efc0924
https://doi.org/10.1074/jbc.m205308200
https://doi.org/10.1074/jbc.m205308200
Publikováno v:
Journal of Biological Chemistry. 277:24376-24381
The complex between the short splice variant of the ninth member of the RGS protein family and the long splice variant of type 5 G protein beta subunit (RGS9-Gbeta5L) plays a critical role in regulating the duration of the light response in vertebrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26c6f561461e757ab567f28da17ff68
https://doi.org/10.1074/jbc.m203237200
https://doi.org/10.1074/jbc.m203237200
Autor:
Arye Elfenbein, Vadim Y. Arshavsky, Andrew Bohm, Kirill A. Martemyanov, Nikolai P. Skiba, William F. Simonds, Johnathan A. Hopp
Publikováno v:
Journal of Biological Chemistry. 276:37365-37372
RGS proteins regulate the duration of G protein signaling by increasing the rate of GTP hydrolysis on G protein alpha subunits. The complex of RGS9 with type 5 G protein beta subunit (G beta 5) is abundant in photoreceptors, where it stimulates the G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed0aa823e90a11f7ee4f17fe131413d8
https://doi.org/10.1074/jbc.m106431200
https://doi.org/10.1074/jbc.m106431200
Autor:
Gabor Keresztes, Vadim Y. Arshavsky, Katherine J. Strissel, Ching-Kang Chen, Kirill A. Martemyanov, Nidia Calero, Janis Lem, Polina V. Lishko, Maxim Sokolov, Ilya Leskov, Stefan Heller, Johnathan A. Hopp, Marie E. Burns, Alexander V. Kolesnikov
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(32)
DEP (for Disheveled, EGL-10, Pleckstrin) homology domains are present in numerous signaling proteins, including many in the nervous system, but their function remains mostly elusive. We report that the DEP domain of a photoreceptor-specific signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a0c27e5e6bf691d3de5e42b1d48de1
https://pubmed.ncbi.nlm.nih.gov/14614075
https://pubmed.ncbi.nlm.nih.gov/14614075
Publikováno v:
Neuron. 38(6)
RGS proteins regulate the duration of cell signaling by modulating the lifetime of activated G proteins. The specificity of RGS-G protein mutual recognition is critical for meeting unique timing requirements of numerous G protein-mediated pathways. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e2893d761964a1151377c3a363829d
https://pubmed.ncbi.nlm.nih.gov/12818171
https://pubmed.ncbi.nlm.nih.gov/12818171
Autor:
Martin, Obin, Bruce Y, Lee, Gretchen, Meinke, Andrew, Bohm, Rehwa H, Lee, Rachelle, Gaudet, Johnathan A, Hopp, Vadim Y, Arshavsky, Barry M, Willardson, Allen, Taylor
Publikováno v:
The Journal of biological chemistry. 277(46)
G proteins (Galphabetagamma) are essential signaling molecules, which dissociate into Galpha and Gbetagamma upon activation by heptahelical membrane receptors. We have identified the betagamma subunit complex of the photoreceptor-specific G protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86db5914bc1cfe967346b2a4d82940c6
https://pubmed.ncbi.nlm.nih.gov/12215439
https://pubmed.ncbi.nlm.nih.gov/12215439
Publikováno v:
The Journal of biological chemistry. 275(42)
The photoreceptor-specific G protein transducin acts as a molecular switch, stimulating the activity of its downstream effector in its GTP-bound form and inactivating the effector upon GTP hydrolysis. This activity makes the rate of transducin GTPase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2606b7ea72e69ce18c85901ff2d8a4
https://pubmed.ncbi.nlm.nih.gov/10973941
https://pubmed.ncbi.nlm.nih.gov/10973941