Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Johnatas D, Silva"'
Autor:
Hector Gonzalez, Sean McCarthy, Claire Masterson, Declan Byrnes, Ignacio Sallent, Emma Horan, Stephen J. Elliman, Gabriele Vella, Adriele Prina-Mello, Johnatas D. Silva, Anna D. Krasnodembskaya, Ronan MacLoughlin, John G. Laffey, Daniel O’Toole
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Background Mesenchymal stem cell (MSC) derived extracellular vesicles (EVs) have been proposed as an alternative to cell therapy, creating new possible delivery modalities such as nebulisation. We wished to investigate the therapeutic potent
Externí odkaz:
https://doaj.org/article/58ea4b1249d540ff964eec605f52e948
Autor:
Johnatas D. Silva, Miquéias Lopes-Pacheco, Ligia L. de Castro, Jamil Z. Kitoko, Stefano A. Trivelin, Natália R. Amorim, Vera L. Capelozzi, Marcelo M. Morales, Bianca Gutfilen, Sergio A. L. de Souza, Daniel J. Weiss, Bruno L. Diaz, Patricia R. M. Rocco
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-16 (2019)
Abstract Background Even though mesenchymal stromal cells (MSCs) mitigate lung and distal organ damage in experimental polymicrobial sepsis, mortality remains high. We investigated whether preconditioning with eicosapentaenoic acid (EPA) would potent
Externí odkaz:
https://doaj.org/article/62292f89b5ca4343b769d7aa0af9d64c
Autor:
Elga Bandeira, Helena Oliveira, Johnatas D. Silva, Rubem F. S. Menna-Barreto, Christina M. Takyia, Jung S. Suk, Kenneth W. Witwer, Michael E. Paulaitis, Justin Hanes, Patricia R. M. Rocco, Marcelo M. Morales
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Silicosis is an occupational disease that affects workers who inhale silica particles, leading to extensive lung fibrosis and ultimately causing respiratory failure. Mesenchymal stromal cells (MSCs) have been shown to exert therap
Externí odkaz:
https://doaj.org/article/e0fce8b21f194a74a8f698ed49fe2d80
Autor:
Johnatas D. Silva, Ligia L. de Castro, Cassia L. Braga, Gisele P. Oliveira, Stefano A. Trivelin, Carlos M. Barbosa-Junior, Marcelo M. Morales, Claudia C. dos Santos, Daniel J. Weiss, Miquéias Lopes-Pacheco, Fernanda F. Cruz, Patricia R. M. Rocco
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Although mesenchymal stromal cells (MSCs) have demonstrated beneficial effects on experimental acute respiratory distress syndrome (ARDS), preconditioning may be required to potentiate their therapeutic effects. Additionally, administration of cell-f
Externí odkaz:
https://doaj.org/article/aa66a863b23f49bc9563f5a35afdd5f4
Autor:
Natália G. Blanco, Natália M. Machado, Ligia L. Castro, Mariana A. Antunes, Christina M. Takiya, Monique R. O. Trugilho, Luana R. Silva, Adriana F. Paes Leme, Romênia R. Domingues, Bianca A. Pauletti, Beatriz T. Miranda, Johnatas D. Silva, Claudia C. dos Santos, Pedro L. Silva, Patricia R. M. Rocco, Fernanda F. Cruz
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8234
The effects of the administration of mesenchymal stromal cells (MSC) may vary according to the source. We hypothesized that MSC-derived extracellular vesicles (EVs) obtained from bone marrow (BM), adipose (AD), or lung (L) tissues may also lead to di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a50daec98b62d2a6a0763865e4e83d8
Autor:
Cassiano Felippe Gonçalves-de-Albuquerque, Ina Rohwedder, Adriana Ribeiro Silva, Alessandra Silveira Ferreira, Angela R. M. Kurz, Céline Cougoule, Sarah Klapproth, Tanja Eggersmann, Johnatas D. Silva, Gisele Pena de Oliveira, Vera Luiza Capelozzi, Gabriel Gutfilen Schlesinger, Edlaine Rijo Costa, Rita de Cassia Elias Estrela Marins, Attila Mócsai, Isabelle Maridonneau-Parini, Barbara Walzog, Patricia Rieken Macedo Rocco, Markus Sperandio, Hugo Caire de Castro-Faria-Neto
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Neutrophils are the first cells of our immune system to arrive at the site of inflammation. They release cytokines, e.g., chemokines, to attract further immune cells, but also actively start to phagocytose and kill pathogens. In the case of sepsis, t
Externí odkaz:
https://doaj.org/article/7ccab5d915944e489b92a4a1299e2b46
Autor:
Gisele P. Oliveira, Johnatas D. Silva, Patricia S. Marques, Cassiano F. Gonçalves-de-Albuquerque, Heloísa L. Santos, Ana Paula Vascocellos, Christina M. Takiya, Marcelo M. Morales, Paolo Pelosi, Attila Mócsai, Hugo C. de Castro-Faria-Neto, Patricia R.M. Rocco
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 4, Pp 1644-1658 (2015)
Background/Aims: Evidence suggests that tyrosine-kinase inhibitors may attenuate lung inflammation and fibrosis in experimental acute respiratory distress syndrome (ARDS). We hypothesized that dasatinib, a tyrosine-kinase inhibitor, might act differe
Externí odkaz:
https://doaj.org/article/8a427a733cba4f93a4128454f3507381
Autor:
Klaus N. Fontes, Adriana Cabanelas, Flavia F. Bloise, Cherley Borba Vieira de Andrade, Luana L. Souza, Marianna Wilieman, Isis H. Trevenzoli, Lais C. Agra, Johnatas D. Silva, Christianne Bandeira-Melo, Pedro L. Silva, Patricia R. M. Rocco, Tania M. Ortiga-Carvalho
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/8c1de7dee06448b39587529ddc32e2c8
Autor:
Klaus N. Fontes, Adriana Cabanelas, Flavia F. Bloise, Cherley Borba Vieira de Andrade, Luana L. Souza, Marianna Wilieman, Isis H. Trevenzoli, Lais C. Agra, Johnatas D. Silva, Christianne Bandeira-Melo, Pedro L. Silva, Patricia R. M. Rocco, Tania M. Ortiga-Carvalho
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Fasting and sepsis induce profound changes in thyroid hormone (TH) central and peripheral metabolism. These changes affect TH action and are called the non-thyroidal illness syndrome (NTIS). To date, it is still debated whether NTIS represents an ada
Externí odkaz:
https://doaj.org/article/d201fcb047d44df2bcd92f57b1be56a7
Autor:
Cintia L Santos, Raquel S Santos, Lillian Moraes, Cynthia S Samary, Nathane S Felix, Johnatas D Silva, Marcelo M Morales, Robert Huhle, Marcelo G Abreu, Alberto Schanaider, Pedro L Silva, Paolo Pelosi, Patricia R M Rocco
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178207 (2017)
Intra-abdominal hypertension (IAH) may co-occur with the acute respiratory distress syndrome (ARDS), with significant impact on morbidity and mortality. Lung-protective controlled mechanical ventilation with low tidal volume and positive end-expirato
Externí odkaz:
https://doaj.org/article/8928de44149f45e0b8b61d6cbabe2cac